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OPENSEQ.org
YCEG - UPF0755 protein YceG
UniProt: P28306 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11494
Length: 340 (337)
Sequences: 1705
Seq/Len: 5.06
YCEG
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
320_L 324_N 5.49 1.00
317_N 326_S 4.324 1.00
319_N 322_S 4.013 1.00
230_S 301_T 3.889 1.00
302_P 318_T 3.887 1.00
232_F 244_T 3.717 1.00
215_I 295_A 3.136 1.00
45_K 48_T 3.097 1.00
215_I 229_A 2.767 1.00
202_Y 211_M 2.646 1.00
58_Y 66_P 2.625 1.00
225_R 291_S 2.522 1.00
211_M 232_F 2.489 1.00
45_K 56_Q 2.475 1.00
224_E 314_H 2.471 1.00
268_P 276_I 2.466 1.00
232_F 306_F 2.462 1.00
209_V 292_L 2.449 1.00
231_V 306_F 2.337 1.00
208_L 296_A 2.264 1.00
244_T 306_F 2.263 1.00
243_Q 305_Y 2.234 1.00
48_T 56_Q 2.202 1.00
214_I 244_T 2.181 1.00
219_T 228_V 2.132 1.00
216_E 225_R 2.116 1.00
268_P 275_T 2.105 1.00
227_K 299_A 2.09 1.00
233_I 295_A 2.089 1.00
211_M 295_A 2.076 1.00
292_L 296_A 2.069 1.00
243_Q 274_Y 2.054 1.00
229_A 295_A 2.038 1.00
241_R 277_T 2.037 1.00
318_T 322_S 2.001 1.00
230_S 299_A 1.992 1.00
309_D 313_G 1.962 1.00
160_W 206_N 1.932 1.00
251_G 269_T 1.88 1.00
43_T 86_T 1.872 1.00
206_N 282_G 1.865 1.00
118_M 126_Q 1.837 1.00
211_M 233_I 1.835 1.00
226_D 299_A 1.83 1.00
230_S 303_Y 1.813 1.00
229_A 233_I 1.813 1.00
210_T 282_G 1.753 1.00
211_M 244_T 1.732 1.00
204_D 207_Q 1.718 1.00
87_Y 105_G 1.715 1.00
246_P 306_F 1.703 1.00
240_M 304_L 1.694 1.00
50_R 73_L 1.668 0.99
289_A 293_K 1.667 0.99
222_A 290_D 1.638 0.99
184_K 187_K 1.592 0.99
227_K 303_Y 1.584 0.99
164_D 184_K 1.574 0.99
221_V 313_G 1.542 0.99
247_T 273_T 1.539 0.99
206_N 210_T 1.538 0.99
173_T 176_A 1.528 0.99
234_N 301_T 1.517 0.99
115_V 118_M 1.492 0.98
214_I 247_T 1.484 0.98
315_T 326_S 1.483 0.98
184_K 188_A 1.461 0.98
239_G 277_T 1.451 0.98
120_L 286_T 1.449 0.98
89_F 98_M 1.438 0.98
240_M 243_Q 1.427 0.98
119_R 122_D 1.427 0.98
192_A 296_A 1.425 0.98
130_A 168_Y 1.411 0.98
142_Y 145_V 1.407 0.98
89_F 93_M 1.404 0.97
123_Y 286_T 1.396 0.97
323_H 327_V 1.392 0.97
315_T 329_D 1.379 0.97
51_L 70_Q 1.373 0.97
252_M 260_L 1.358 0.97
113_R 165_T 1.348 0.97
90_T 93_M 1.345 0.97
42_F 56_Q 1.34 0.96
227_K 301_T 1.337 0.96
248_V 265_L 1.335 0.96
93_M 98_M 1.321 0.96
231_V 316_F 1.319 0.96
188_A 289_A 1.311 0.96
224_E 316_F 1.31 0.96
125_K 129_E 1.295 0.95
86_T 110_F 1.293 0.95
39_E 88_R 1.291 0.95
208_L 292_L 1.283 0.95
114_L 123_Y 1.282 0.95
332_K 336_E 1.277 0.95
54_G 69_F 1.275 0.95
20_G 24_W 1.26 0.94
69_F 73_L 1.258 0.94
196_R 200_L 1.242 0.94
262_R 265_L 1.238 0.94
116_E 288_G 1.229 0.93
111_P 167_M 1.227 0.93
214_I 306_F 1.223 0.93
217_K 249_I 1.218 0.93
327_V 331_L 1.205 0.93
101_L 104_S 1.199 0.92
54_G 70_Q 1.183 0.92
232_F 246_P 1.181 0.92
185_M 189_V 1.178 0.91
252_M 267_T 1.178 0.91
273_T 280_P 1.166 0.91
217_K 285_A 1.16 0.91
246_P 308_A 1.159 0.91
251_G 267_T 1.155 0.90
44_L 56_Q 1.149 0.90
115_V 126_Q 1.143 0.90
274_Y 323_H 1.134 0.89
189_V 209_V 1.132 0.89
188_A 191_S 1.128 0.89
266_E 275_T 1.112 0.88
216_E 291_S 1.11 0.88
18_A 21_V 1.106 0.88
269_T 276_I 1.103 0.87
228_V 311_K 1.101 0.87
42_F 62_I 1.1 0.87
238_I 304_L 1.097 0.87
307_V 327_V 1.097 0.87
295_A 298_P 1.095 0.87
193_W 196_R 1.094 0.87
185_M 287_P 1.094 0.87
241_R 276_I 1.084 0.86
319_N 323_H 1.075 0.86
197_A 200_L 1.069 0.85
96_R 100_K 1.066 0.85
271_Y 282_G 1.065 0.85
201_P 233_I 1.06 0.84
101_L 106_K 1.057 0.84
248_V 260_L 1.051 0.84
162_W 184_K 1.04 0.83
185_M 209_V 1.039 0.83
56_Q 60_D 1.038 0.83
263_A 267_T 1.03 0.82
271_Y 281_P 1.022 0.81
162_W 185_M 1.022 0.81
57_L 62_I 1.021 0.81
325_K 329_D 1.017 0.81
168_Y 177_L 1.013 0.81
308_A 313_G 1.005 0.80
116_E 162_W 1.004 0.80
146_A 151_L 1 0.79
321_A 324_N 1 0.79
161_F 178_L 1 0.79
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4iiwA20.96761000.106Contact Map0.744
2r1fA20.79411000.158Contact Map0.745
4f55A10.314791.80.948Contact Map0.438
4fetB20.5565.50.961Contact Map0.483
3v4yB40.129417.20.972Contact Map0.155
2v3sA20.267613.60.973Contact Map0.225
1scfA40.176511.50.974Contact Map
4b8vA10.597111.10.974Contact Map0.462
1e0gA10.14129.80.975Contact Map0.374
2kgwA10.173580.976Contact Map0.383
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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