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OPENSEQ.org
YIGZ - IMPACT family member YigZ
UniProt: P27862 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11484
Length: 204 (200)
Sequences: 1313
Seq/Len: 6.57
YIGZ
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_C 83_M 3.357 1.00
29_T 96_T 3.064 1.00
97_A 121_V 2.971 1.00
26_L 97_A 2.918 1.00
83_M 121_V 2.86 1.00
78_T 110_T 2.837 1.00
103_Y 107_L 2.732 1.00
14_V 21_R 2.717 1.00
25_M 100_V 2.52 1.00
38_F 96_T 2.471 1.00
52_H 100_V 2.446 1.00
43_R 72_D 2.258 1.00
52_H 98_V 2.234 1.00
15_E 119_G 2.156 1.00
181_K 184_E 2.141 1.00
24_T 120_G 2.115 1.00
25_M 46_H 2.103 1.00
41_S 45_E 1.951 1.00
27_A 38_F 1.936 1.00
148_L 173_L 1.911 1.00
13_V 123_Q 1.878 1.00
39_V 96_T 1.847 1.00
67_L 88_M 1.832 1.00
25_M 42_V 1.803 1.00
30_D 34_A 1.785 1.00
23_I 102_Y 1.768 1.00
15_E 120_G 1.765 1.00
83_M 99_V 1.751 1.00
90_S 126_R 1.749 1.00
189_L 197_L 1.694 1.00
148_L 167_Y 1.68 1.00
7_P 26_L 1.677 1.00
87_L 121_V 1.617 1.00
35_A 39_V 1.563 0.99
140_T 172_L 1.552 0.99
19_K 106_I 1.551 0.99
61_P 65_Q 1.538 0.99
27_A 96_T 1.536 0.99
44_A 47_P 1.516 0.99
57_V 88_M 1.485 0.99
143_C 151_I 1.484 0.99
193_S 197_L 1.471 0.99
166_D 172_L 1.459 0.99
31_G 34_A 1.443 0.99
12_T 45_E 1.402 0.99
152_E 156_G 1.402 0.99
183_A 186_S 1.398 0.99
32_V 36_K 1.381 0.98
87_L 97_A 1.378 0.98
26_L 121_V 1.358 0.98
83_M 87_L 1.352 0.98
4_W 133_K 1.347 0.98
85_A 88_M 1.34 0.98
137_T 179_A 1.331 0.98
32_V 68_G 1.306 0.97
148_L 152_E 1.303 0.97
50_R 103_Y 1.3 0.97
53_C 79_A 1.298 0.97
155_L 160_G 1.273 0.97
142_Q 172_L 1.263 0.97
152_E 165_S 1.237 0.96
123_Q 126_R 1.222 0.96
24_T 97_A 1.214 0.96
141_L 175_V 1.208 0.95
111_G 115_K 1.189 0.95
38_F 52_H 1.184 0.95
42_V 46_H 1.183 0.95
42_V 100_V 1.181 0.95
45_E 48_D 1.172 0.94
24_T 121_V 1.17 0.94
15_E 123_Q 1.17 0.94
24_T 124_A 1.169 0.94
43_R 52_H 1.127 0.93
183_A 187_A 1.127 0.93
54_V 70_S 1.11 0.92
153_A 157_Q 1.106 0.92
35_A 52_H 1.086 0.91
138_E 176_A 1.086 0.91
185_F 188_K 1.085 0.91
42_V 98_V 1.076 0.90
17_I 106_I 1.073 0.90
47_P 52_H 1.067 0.90
90_S 122_N 1.065 0.90
50_R 107_L 1.061 0.89
187_A 191_D 1.059 0.89
57_V 67_L 1.054 0.89
59_G 93_G 1.052 0.89
13_V 120_G 1.051 0.89
186_S 199_L 1.048 0.89
43_R 54_V 1.044 0.88
140_T 174_R 1.04 0.88
25_M 52_H 1.037 0.88
135_P 179_A 1.033 0.88
140_T 200_L 1.01 0.86
38_F 98_V 1.006 0.86
149_T 152_E 1.004 0.86
168_Q 172_L 1.003 0.86
163_I 176_A 1 0.85
166_D 174_R 1 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1vi7A111000.086Contact Map0.683
2cveA10.93141000.142Contact Map0.755
3lh2S40.367698.80.84Contact Map0.771
3j3az10.95194.80.915Contact Map0.495
1n0uA10.9412920.924Contact Map0.621
3j25A10.892290.70.926Contact Map0.315
4fn5A10.90290.70.926Contact Map0.519
2xexA20.90289.90.927Contact Map0.504
1darA10.90289.90.927Contact Map0.533
4kiyV10.897188.30.929Contact Map0.45
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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