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OPENSEQ.org

YEIB - Uncharacterized protein YeiB
UniProt: P25747 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11290
Length: 385 (377)
Sequences: 779
Seq/Len: 2.07

YEIB
Paralog alert: 0.19 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
313_L 364_V 5.251 1.00
311_N 352_S 4.591 1.00
92_V 112_G 4.098 1.00
88_L 115_G 2.962 1.00
67_L 215_L 2.549 1.00
102_F 316_T 2.496 1.00
332_F 340_F 2.451 1.00
121_L 210_L 2.438 1.00
85_Q 116_L 2.409 1.00
307_M 355_W 2.313 1.00
90_L 371_L 2.291 1.00
74_Q 216_M 2.258 1.00
361_Q 366_W 2.246 1.00
92_V 109_L 2.179 1.00
90_L 94_L 1.968 0.99
14_A 17_G 1.935 0.99
310_T 351_F 1.93 0.99
21_L 57_G 1.873 0.98
354_I 358_Y 1.863 0.98
74_Q 213_A 1.842 0.98
71_A 216_M 1.81 0.98
98_H 316_T 1.798 0.98
311_N 348_N 1.793 0.98
97_I 102_F 1.79 0.98
310_T 314_L 1.777 0.97
52_F 56_I 1.777 0.97
318_I 344_V 1.741 0.97
128_V 217_R 1.709 0.97
8_D 11_R 1.675 0.96
354_I 359_F 1.666 0.96
18_I 316_T 1.654 0.96
22_N 103_W 1.654 0.96
73_L 118_C 1.654 0.96
307_M 356_L 1.643 0.95
61_F 308_A 1.633 0.95
134_T 210_L 1.615 0.95
366_W 370_Q 1.583 0.94
21_L 58_Q 1.561 0.93
19_L 319_C 1.522 0.92
16_L 345_W 1.521 0.92
304_V 311_N 1.508 0.92
132_F 214_A 1.506 0.92
9_F 301_I 1.478 0.91
103_W 106_D 1.445 0.89
121_L 134_T 1.442 0.89
177_H 181_E 1.423 0.88
370_Q 377_G 1.4 0.87
17_G 61_F 1.397 0.87
360_R 366_W 1.396 0.87
105_G 316_T 1.396 0.87
350_L 354_I 1.395 0.87
303_C 353_V 1.385 0.87
112_G 353_V 1.376 0.86
300_A 303_C 1.373 0.86
93_L 371_L 1.367 0.86
71_A 215_L 1.351 0.85
7_L 359_F 1.332 0.84
320_T 326_L 1.314 0.82
4_N 286_Y 1.306 0.82
88_L 368_W 1.305 0.82
63_T 274_A 1.304 0.82
103_W 352_S 1.304 0.82
64_L 282_A 1.301 0.82
14_A 355_W 1.297 0.81
304_V 349_I 1.292 0.81
22_N 86_S 1.288 0.81
3_R 7_L 1.284 0.80
352_S 356_L 1.278 0.80
354_I 357_R 1.273 0.80
62_L 315_Q 1.272 0.80
12_G 16_L 1.271 0.79
347_A 354_I 1.271 0.79
98_H 103_W 1.259 0.79
315_Q 348_N 1.258 0.79
128_V 218_S 1.253 0.78
60_K 277_Q 1.25 0.78
97_I 101_L 1.249 0.78
353_V 357_R 1.247 0.78
356_L 359_F 1.246 0.78
22_N 98_H 1.244 0.77
71_A 308_A 1.243 0.77
322_L 328_L 1.243 0.77
213_A 216_M 1.24 0.77
86_S 369_R 1.239 0.77
72_G 103_W 1.232 0.76
88_L 112_G 1.225 0.76
60_K 63_T 1.225 0.76
88_L 116_L 1.224 0.76
319_C 344_V 1.223 0.76
62_L 66_A 1.22 0.75
9_F 302_A 1.215 0.75
214_A 218_S 1.214 0.75
22_N 72_G 1.206 0.74
5_V 302_A 1.205 0.74
91_L 359_F 1.204 0.74
320_T 324_Y 1.203 0.74
236_V 240_I 1.202 0.74
18_I 65_F 1.192 0.73
3_R 8_D 1.191 0.73
361_Q 370_Q 1.184 0.72
306_R 356_L 1.177 0.72
213_A 286_Y 1.173 0.71
303_C 309_L 1.171 0.71
94_L 368_W 1.166 0.71
349_I 353_V 1.166 0.71
73_L 122_V 1.165 0.71
308_A 311_N 1.157 0.70
301_I 349_I 1.156 0.70
130_S 133_N 1.153 0.69
148_L 310_T 1.147 0.69
311_N 356_L 1.145 0.69
10_V 348_N 1.144 0.69
94_L 309_L 1.142 0.68
219_G 222_K 1.138 0.68
112_G 303_C 1.136 0.68
203_W 209_M 1.129 0.67
9_F 285_F 1.126 0.67
112_G 308_A 1.123 0.67
16_L 304_V 1.118 0.66
20_L 57_G 1.116 0.66
10_V 13_V 1.111 0.65
355_W 359_F 1.108 0.65
101_L 297_L 1.108 0.65
3_R 11_R 1.108 0.65
57_G 97_I 1.107 0.65
108_L 309_L 1.102 0.64
72_G 75_M 1.102 0.64
49_T 117_I 1.1 0.64
76_L 221_L 1.1 0.64
62_L 69_F 1.099 0.64
98_H 281_Y 1.097 0.64
72_G 213_A 1.095 0.64
284_L 287_G 1.089 0.63
20_L 341_V 1.087 0.63
3_R 12_G 1.087 0.63
202_G 367_L 1.077 0.62
98_H 105_G 1.073 0.61
265_L 310_T 1.069 0.61
185_N 189_G 1.067 0.61
221_L 301_I 1.066 0.61
22_N 241_G 1.063 0.60
7_L 72_G 1.06 0.60
109_L 112_G 1.059 0.60
284_L 288_F 1.056 0.60
8_D 12_G 1.054 0.59
17_G 22_N 1.054 0.59
94_L 371_L 1.054 0.59
69_F 88_L 1.046 0.58
15_I 308_A 1.042 0.58
18_I 62_L 1.041 0.58
135_G 214_A 1.041 0.58
14_A 60_K 1.04 0.58
26_F 323_F 1.039 0.58
320_T 325_H 1.036 0.57
7_L 368_W 1.036 0.57
60_K 274_A 1.034 0.57
318_I 322_L 1.033 0.57
13_V 301_I 1.032 0.57
85_Q 119_W 1.031 0.57
44_P 56_I 1.029 0.57
125_A 130_S 1.026 0.56
98_H 106_D 1.025 0.56
73_L 84_I 1.022 0.56
68_L 311_N 1.021 0.56
209_M 372_T 1.018 0.55
90_L 368_W 1.017 0.55
103_W 308_A 1.017 0.55
88_L 348_N 1.012 0.55
117_I 192_N 1.012 0.55
89_T 93_L 1.007 0.54
124_D 130_S 1.007 0.54
105_G 369_R 1.003 0.54
62_L 98_H 1.001 0.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1wazA10.11954.80.974Contact Map0.241
3a6pA20.15322.60.977Contact Map
2o5gB10.05452.30.978Contact Map1
1qtxB10.054520.978Contact Map0.54
4g9jC20.031220.979Contact Map
4lx2B10.02861.60.98Contact Map
3ukxC10.03121.50.98Contact Map
2f8eA10.04941.40.98Contact Map
4kp3E20.05451.10.981Contact Map
1zo0A10.10911.10.982Contact Map0.212

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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