| UniProt: | P24224 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10247 | ||
| Length: | 126 (125) | ||
| Sequences: | 1520 | ||
| Seq/Len: | 12.16 |
| ACPS
Paralog alert: 0.06 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 52_K | 111_L | 3.329 | 1.00 | |
| 108_H | 125_E | 2.721 | 1.00 | |
| 52_K | 113_D | 2.538 | 1.00 | |
| 96_L | 100_E | 2.536 | 1.00 | |
| 60_A | 89_L | 2.471 | 1.00 | |
| 56_V | 109_V | 2.444 | 1.00 | |
| 33_S | 78_E | 2.412 | 1.00 | |
| 8_T | 119_C | 2.206 | 1.00 | |
| 60_A | 122_V | 2.202 | 1.00 | |
| 8_T | 121_T | 2.197 | 1.00 | |
| 35_N | 78_E | 2.192 | 1.00 | |
| 6_L | 121_T | 2.191 | 1.00 | |
| 89_L | 122_V | 2.181 | 1.00 | |
| 112_A | 119_C | 2.176 | 1.00 | |
| 17_E | 21_A | 2.048 | 1.00 | |
| 28_A | 37_W | 1.973 | 1.00 | |
| 56_V | 79_V | 1.909 | 1.00 | |
| 82_D | 86_K | 1.905 | 1.00 | |
| 80_F | 88_R | 1.845 | 1.00 | |
| 12_E | 116_H | 1.843 | 1.00 | |
| 53_R | 81_N | 1.842 | 1.00 | |
| 12_E | 114_E | 1.811 | 1.00 | |
| 55_A | 120_A | 1.806 | 1.00 | |
| 10_I | 117_Y | 1.73 | 1.00 | |
| 61_A | 68_I | 1.664 | 1.00 | |
| 8_T | 110_T | 1.656 | 1.00 | |
| 99_A | 104_V | 1.608 | 1.00 | |
| 10_I | 119_C | 1.503 | 1.00 | |
| 40_W | 50_L | 1.462 | 1.00 | |
| 19_V | 23_S | 1.429 | 1.00 | |
| 98_L | 102_L | 1.406 | 0.99 | |
| 5_G | 108_H | 1.395 | 0.99 | |
| 29_R | 34_D | 1.37 | 0.99 | |
| 48_R | 113_D | 1.355 | 0.99 | |
| 106_N | 125_E | 1.355 | 0.99 | |
| 3_I | 108_H | 1.349 | 0.99 | |
| 13_I | 118_A | 1.332 | 0.99 | |
| 29_R | 37_W | 1.33 | 0.99 | |
| 14_A | 116_H | 1.328 | 0.99 | |
| 37_W | 50_L | 1.265 | 0.99 | |
| 11_V | 55_A | 1.264 | 0.99 | |
| 68_I | 74_F | 1.262 | 0.99 | |
| 27_L | 31_V | 1.256 | 0.99 | |
| 60_A | 64_F | 1.249 | 0.99 | |
| 94_E | 97_K | 1.248 | 0.99 | |
| 91_L | 107_M | 1.242 | 0.98 | |
| 32_L | 40_W | 1.242 | 0.98 | |
| 25_D | 29_R | 1.232 | 0.98 | |
| 13_I | 47_V | 1.229 | 0.98 | |
| 37_W | 41_K | 1.21 | 0.98 | |
| 32_L | 50_L | 1.204 | 0.98 | |
| 80_F | 90_R | 1.198 | 0.98 | |
| 41_K | 50_L | 1.188 | 0.98 | |
| 40_W | 49_F | 1.185 | 0.98 | |
| 107_M | 124_I | 1.159 | 0.97 | |
| 11_V | 16_I | 1.14 | 0.97 | |
| 77_F | 89_L | 1.118 | 0.96 | |
| 32_L | 49_F | 1.115 | 0.96 | |
| 60_A | 77_F | 1.113 | 0.96 | |
| 11_V | 118_A | 1.107 | 0.96 | |
| 39_I | 81_N | 1.104 | 0.96 | |
| 8_T | 112_A | 1.095 | 0.96 | |
| 82_D | 88_R | 1.086 | 0.96 | |
| 5_G | 125_E | 1.059 | 0.95 | |
| 61_A | 72_L | 1.047 | 0.94 | |
| 78_E | 92_W | 1.04 | 0.94 | |
| 98_L | 101_K | 1.038 | 0.94 | |
| 55_A | 118_A | 1.037 | 0.94 | |
| 97_K | 100_E | 1.014 | 0.93 | |
| 114_E | 117_Y | 1.01 | 0.93 | |
| 13_I | 51_A | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2uv9A | 6 | 0.9683 | 100 | 0.089 | Contact Map | |
| 2uv8A | 3 | 0.9683 | 100 | 0.092 | Contact Map | |
| 2bddA | 1 | 0.9921 | 100 | 0.149 | Contact Map | 0.672 |
| 2qg8A | 1 | 0.9921 | 100 | 0.161 | Contact Map | 0.675 |
| 3h88A | 24 | 1 | 100 | 0.193 | Contact Map | 0.901 |
| 3nfdA | 6 | 0.9683 | 100 | 0.193 | Contact Map | 0.742 |
| 2wdsA | 1 | 0.9762 | 100 | 0.194 | Contact Map | 0.62 |
| 3gwmA | 1 | 0.9603 | 100 | 0.233 | Contact Map | 0.599 |
| 3hykA | 3 | 0.9127 | 100 | 0.284 | Contact Map | 0.865 |
| 3f09A | 3 | 0.9048 | 100 | 0.29 | Contact Map | 0.849 |
Sequence Conservation (Image Generated using WebLogo v3)