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FECC - Fe(3+) dicitrate transport system permease protein FecC
UniProt: P15030 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10288
Length: 332 (310)
Sequences: 6160
Seq/Len: 19.87
FECC
Paralog alert: 0.85 [within 20: 0.62] - ratio of genomes with paralogs
Cluster includes: BTUC FECC FECD FEPD FEPG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
219_N 278_D 5.346 1.00
72_A 287_M 4.292 1.00
80_L 242_I 3.324 1.00
68_V 291_A 3.253 1.00
234_N 237_R 3.118 1.00
108_T 124_I 3.084 1.00
73_S 249_L 2.993 1.00
67_A 189_V 2.972 1.00
271_A 289_L 2.92 1.00
80_L 211_V 2.917 1.00
66_V 192_A 2.767 1.00
73_S 204_V 2.668 1.00
225_D 239_R 2.562 1.00
76_L 287_M 2.554 1.00
28_C 36_G 2.463 1.00
73_S 253_C 2.453 1.00
38_D 41_R 2.43 1.00
70_I 257_A 2.405 1.00
103_L 163_C 2.383 1.00
68_V 295_L 2.323 1.00
79_T 286_S 2.322 1.00
275_A 285_V 2.219 1.00
219_N 279_Q 2.174 1.00
26_L 64_S 2.131 1.00
70_I 253_C 2.122 1.00
63_R 298_D 2.101 1.00
103_L 166_L 2.08 1.00
83_T 279_Q 1.973 1.00
129_G 251_G 1.947 1.00
81_L 246_V 1.912 1.00
35_S 38_D 1.87 1.00
198_W 202_P 1.831 1.00
76_L 208_V 1.825 1.00
65_L 197_V 1.815 1.00
263_I 294_M 1.77 1.00
271_A 285_V 1.714 1.00
300_L 304_L 1.713 1.00
237_R 241_V 1.71 1.00
220_L 233_V 1.694 1.00
189_V 294_M 1.691 1.00
302_R 309_D 1.666 1.00
217_Q 238_L 1.661 1.00
106_A 167_T 1.647 1.00
192_A 196_D 1.639 1.00
267_V 293_L 1.616 1.00
203_V 252_A 1.607 1.00
301_A 312_A 1.594 1.00
66_V 256_V 1.569 1.00
279_Q 282_V 1.552 1.00
84_L 242_I 1.517 1.00
102_A 167_T 1.516 1.00
300_L 315_V 1.49 1.00
202_P 206_T 1.478 1.00
206_T 209_P 1.477 1.00
37_A 41_R 1.477 1.00
193_R 196_D 1.474 1.00
271_A 282_V 1.468 1.00
75_A 267_V 1.463 1.00
214_L 217_Q 1.459 1.00
198_W 201_L 1.447 1.00
214_L 241_V 1.426 1.00
25_S 28_C 1.414 1.00
77_A 249_L 1.4 0.99
79_T 282_V 1.398 0.99
69_L 201_L 1.386 0.99
27_F 64_S 1.374 0.99
42_A 57_Q 1.372 0.99
236_T 239_R 1.365 0.99
67_A 294_M 1.341 0.99
133_W 247_L 1.336 0.99
107_L 111_L 1.315 0.99
298_D 302_R 1.311 0.99
79_T 279_Q 1.308 0.99
105_M 125_A 1.3 0.99
129_G 247_L 1.286 0.99
281_N 284_P 1.284 0.99
279_Q 284_P 1.284 0.99
136_V 159_L 1.28 0.99
38_D 52_P 1.276 0.99
132_S 163_C 1.27 0.99
229_H 236_T 1.261 0.99
23_W 64_S 1.257 0.99
34_V 56_V 1.249 0.99
207_A 249_L 1.246 0.98
72_A 291_A 1.245 0.98
104_A 124_I 1.229 0.98
39_A 56_V 1.219 0.98
282_V 286_S 1.218 0.98
210_V 214_L 1.205 0.98
194_W 197_V 1.202 0.98
98_N 250_V 1.202 0.98
64_S 299_V 1.194 0.98
131_V 135_L 1.194 0.98
134_L 138_T 1.187 0.98
25_S 29_Y 1.183 0.98
22_F 296_L 1.181 0.98
162_F 321_S 1.18 0.98
26_L 299_V 1.169 0.97
126_A 130_G 1.167 0.97
260_V 294_M 1.161 0.97
69_L 200_L 1.161 0.97
67_A 295_L 1.159 0.97
317_A 322_P 1.159 0.97
224_S 228_A 1.158 0.97
126_A 248_L 1.155 0.97
104_A 128_G 1.154 0.97
98_N 259_P 1.153 0.97
210_V 245_L 1.153 0.97
102_A 185_L 1.146 0.97
69_L 197_V 1.143 0.97
207_A 248_L 1.142 0.97
57_Q 61_L 1.13 0.97
48_T 52_P 1.12 0.96
103_L 107_L 1.117 0.96
238_L 241_V 1.114 0.96
267_V 271_A 1.112 0.96
23_W 68_V 1.109 0.96
281_N 285_V 1.102 0.96
237_R 240_L 1.1 0.96
301_A 311_P 1.1 0.96
227_T 230_T 1.092 0.96
40_T 44_L 1.092 0.96
79_T 283_L 1.091 0.96
201_L 205_V 1.091 0.96
292_T 296_L 1.091 0.96
107_L 170_T 1.089 0.96
32_I 55_L 1.087 0.96
200_L 204_V 1.084 0.96
271_A 274_W 1.078 0.95
214_L 242_I 1.071 0.95
284_P 287_M 1.07 0.95
100_G 128_G 1.068 0.95
207_A 245_L 1.067 0.95
63_R 302_R 1.067 0.95
300_L 303_A 1.063 0.95
42_A 53_E 1.059 0.95
214_L 238_L 1.058 0.95
257_A 260_V 1.053 0.95
253_C 257_A 1.052 0.95
123_F 127_C 1.047 0.94
46_G 53_E 1.032 0.94
99_S 163_C 1.031 0.94
323_C 326_W 1.017 0.93
100_G 132_S 1.013 0.93
294_M 316_L 1.007 0.93
33_P 36_G 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4g1uA20.97891000.153Contact Map0.817
2nq2A20.97591000.169Contact Map0.835
2qi9A20.95781000.174Contact Map0.82
2l9uA20.07834.10.974Contact Map0.282
2x2vA130.20481.20.98Contact Map0.457
2m20A20.069310.981Contact Map0.345
2ksdA10.201810.981Contact Map0.264
3bz1y10.12650.70.983Contact Map0.373
2jx5A10.11450.70.983Contact Map0
3rlfF10.40960.60.984Contact Map0.372
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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