| UniProt: | P0CF60 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG60055 | ||
| Length: | 218 (202) | ||
| Sequences: | 3632 | ||
| Seq/Len: | 17.98 |
| INSD8
Paralog alert: 0.70 [within 20: 0.17] - ratio of genomes with paralogs Cluster includes: INSD1 INSD2 INSD3 INSD4 INSD5 INSD6 INSD8 INSF1 INSF2 INSF3 INSF4 INSF5 INSK INSO1 INSO2 YAGA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 196_R | 204_Q | 2.93 | 1.00 | |
| 65_F | 154_V | 2.651 | 1.00 | |
| 182_E | 186_E | 2.633 | 1.00 | |
| 47_C | 150_A | 2.62 | 1.00 | |
| 98_E | 128_F | 2.59 | 1.00 | |
| 41_E | 44_Q | 2.552 | 1.00 | |
| 43_N | 46_W | 2.413 | 1.00 | |
| 73_E | 199_R | 2.367 | 1.00 | |
| 197_S | 200_E | 2.344 | 1.00 | |
| 167_K | 176_N | 2.322 | 1.00 | |
| 168_P | 172_T | 2.281 | 1.00 | |
| 5_N | 8_R | 2.208 | 1.00 | |
| 186_E | 199_R | 2.169 | 1.00 | |
| 78_A | 95_G | 2.145 | 1.00 | |
| 169_D | 172_T | 1.998 | 1.00 | |
| 52_E | 60_R | 1.971 | 1.00 | |
| 126_R | 136_P | 1.928 | 1.00 | |
| 48_S | 114_T | 1.922 | 1.00 | |
| 40_K | 44_Q | 1.915 | 1.00 | |
| 64_T | 120_Y | 1.869 | 1.00 | |
| 173_A | 177_L | 1.822 | 1.00 | |
| 8_R | 11_R | 1.802 | 1.00 | |
| 4_I | 9_V | 1.796 | 1.00 | |
| 185_N | 188_H | 1.748 | 1.00 | |
| 63_V | 157_I | 1.717 | 1.00 | |
| 157_I | 177_L | 1.673 | 1.00 | |
| 72_R | 190_H | 1.671 | 1.00 | |
| 39_V | 45_R | 1.669 | 1.00 | |
| 161_Y | 167_K | 1.665 | 1.00 | |
| 47_C | 69_C | 1.661 | 1.00 | |
| 73_E | 202_L | 1.63 | 1.00 | |
| 90_Q | 94_L | 1.62 | 1.00 | |
| 48_S | 112_W | 1.55 | 1.00 | |
| 191_S | 195_Y | 1.549 | 1.00 | |
| 155_K | 159_R | 1.546 | 1.00 | |
| 193_L | 197_S | 1.521 | 1.00 | |
| 110_V | 134_L | 1.519 | 1.00 | |
| 128_F | 132_L | 1.514 | 1.00 | |
| 161_Y | 176_N | 1.495 | 1.00 | |
| 50_G | 119_C | 1.437 | 1.00 | |
| 36_R | 45_R | 1.425 | 1.00 | |
| 48_S | 120_Y | 1.419 | 1.00 | |
| 65_F | 150_A | 1.408 | 1.00 | |
| 160_D | 188_H | 1.397 | 0.99 | |
| 31_R | 35_G | 1.381 | 0.99 | |
| 10_Y | 14_R | 1.375 | 0.99 | |
| 152_S | 155_K | 1.37 | 0.99 | |
| 12_I | 16_N | 1.369 | 0.99 | |
| 196_R | 201_Y | 1.369 | 0.99 | |
| 116_N | 141_V | 1.354 | 0.99 | |
| 53_F | 177_L | 1.352 | 0.99 | |
| 69_C | 149_I | 1.35 | 0.99 | |
| 139_T | 146_S | 1.348 | 0.99 | |
| 140_A | 146_S | 1.333 | 0.99 | |
| 61_L | 170_G | 1.331 | 0.99 | |
| 193_L | 201_Y | 1.327 | 0.99 | |
| 112_W | 125_T | 1.324 | 0.99 | |
| 47_C | 149_I | 1.312 | 0.99 | |
| 63_V | 77_W | 1.312 | 0.99 | |
| 140_A | 143_S | 1.303 | 0.99 | |
| 88_T | 119_C | 1.3 | 0.99 | |
| 46_W | 110_V | 1.277 | 0.99 | |
| 46_W | 100_R | 1.276 | 0.99 | |
| 145_E | 148_G | 1.274 | 0.99 | |
| 85_N | 89_V | 1.267 | 0.99 | |
| 129_A | 134_L | 1.266 | 0.99 | |
| 67_L | 74_A | 1.256 | 0.99 | |
| 46_W | 66_A | 1.255 | 0.99 | |
| 129_A | 136_P | 1.241 | 0.98 | |
| 70_C | 205_R | 1.238 | 0.98 | |
| 94_L | 128_F | 1.221 | 0.98 | |
| 45_R | 69_C | 1.221 | 0.98 | |
| 78_A | 99_R | 1.219 | 0.98 | |
| 182_E | 187_W | 1.216 | 0.98 | |
| 71_D | 202_L | 1.214 | 0.98 | |
| 101_F | 134_L | 1.213 | 0.98 | |
| 33_H | 45_R | 1.207 | 0.98 | |
| 127_Q | 131_M | 1.204 | 0.98 | |
| 53_F | 162_I | 1.202 | 0.98 | |
| 88_T | 118_S | 1.195 | 0.98 | |
| 67_L | 150_A | 1.192 | 0.98 | |
| 51_F | 158_K | 1.172 | 0.98 | |
| 33_H | 37_V | 1.167 | 0.97 | |
| 178_A | 182_E | 1.143 | 0.97 | |
| 7_K | 10_Y | 1.141 | 0.97 | |
| 116_N | 138_N | 1.134 | 0.97 | |
| 31_R | 34_T | 1.128 | 0.97 | |
| 118_S | 122_A | 1.124 | 0.97 | |
| 170_G | 174_A | 1.123 | 0.97 | |
| 126_R | 130_R | 1.123 | 0.97 | |
| 52_E | 62_R | 1.121 | 0.97 | |
| 113_L | 137_K | 1.119 | 0.96 | |
| 86_S | 170_G | 1.119 | 0.96 | |
| 61_L | 173_A | 1.108 | 0.96 | |
| 176_N | 179_E | 1.104 | 0.96 | |
| 153_F | 157_I | 1.1 | 0.96 | |
| 190_H | 193_L | 1.095 | 0.96 | |
| 56_D | 59_E | 1.088 | 0.96 | |
| 101_F | 132_L | 1.084 | 0.96 | |
| 90_Q | 124_E | 1.063 | 0.95 | |
| 184_Y | 188_H | 1.056 | 0.95 | |
| 4_I | 8_R | 1.039 | 0.94 | |
| 8_R | 12_I | 1.033 | 0.94 | |
| 90_Q | 122_A | 1.031 | 0.94 | |
| 48_S | 64_T | 1.015 | 0.93 | |
| 74_A | 181_F | 1.012 | 0.93 | |
| 165_M | 176_N | 1.006 | 0.93 | |
| 94_L | 98_E | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4fcyA | 2 | 0.9587 | 100 | 0.494 | Contact Map | 0.492 |
| 1bcoA | 1 | 0.8486 | 100 | 0.519 | Contact Map | 0.488 |
| 3av9A | 2 | 0.8303 | 100 | 0.532 | Contact Map | 0.422 |
| 4fw1A | 2 | 0.8073 | 100 | 0.532 | Contact Map | 0.62 |
| 3kksA | 2 | 0.6972 | 100 | 0.543 | Contact Map | 0.595 |
| 3l3uA | 2 | 0.7431 | 100 | 0.547 | Contact Map | 0.633 |
| 1c6vA | 4 | 0.7523 | 100 | 0.547 | Contact Map | 0.67 |
| 3hotA | 2 | 0.945 | 100 | 0.554 | Contact Map | 0.568 |
| 1ex4A | 2 | 0.7661 | 100 | 0.557 | Contact Map | 0.59 |
| 3oymA | 2 | 0.9404 | 100 | 0.562 | Contact Map | 0.699 |
Sequence Conservation (Image Generated using WebLogo v3)