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OPENSEQ.org
PSTC - Phosphate transport system permease protein PstC
UniProt: P0AGH8 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10784
Length: 319 (286)
Sequences: 18160
Seq/Len: 63.50
PSTC
Paralog alert: 0.92 [within 20: 0.69] - ratio of genomes with paralogs
Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
213_E 217_R 4.458 1.00
41_L 57_L 3.905 1.00
210_T 213_E 3.205 1.00
212_W 216_W 2.901 1.00
76_Y 80_V 2.848 1.00
205_Y 214_V 2.83 1.00
84_I 174_G 2.626 1.00
102_E 201_K 2.605 1.00
55_A 58_W 2.574 1.00
55_A 59_T 2.56 1.00
201_K 219_V 2.53 1.00
189_M 227_V 2.504 1.00
190_R 194_E 2.47 1.00
94_F 215_I 2.435 1.00
74_P 270_A 2.365 1.00
73_V 76_Y 2.334 1.00
88_I 178_A 2.319 1.00
72_L 76_Y 2.307 1.00
204_A 214_V 2.292 1.00
211_T 214_V 2.165 1.00
169_G 264_G 2.025 1.00
38_I 292_L 2.023 1.00
209_C 213_E 2.012 1.00
90_V 231_I 2.012 1.00
39_V 43_I 1.985 1.00
265_N 273_N 1.974 1.00
193_F 223_T 1.973 1.00
101_T 194_E 1.897 1.00
147_V 153_N 1.89 1.00
82_S 235_L 1.86 1.00
213_E 216_W 1.802 1.00
205_Y 211_T 1.779 1.00
58_W 67_D 1.753 1.00
93_S 185_I 1.748 1.00
73_V 77_G 1.748 1.00
97_A 189_M 1.745 1.00
134_I 143_F 1.743 1.00
35_G 39_V 1.74 1.00
94_F 189_M 1.709 1.00
201_K 214_V 1.696 1.00
192_V 226_G 1.677 1.00
204_A 209_C 1.666 1.00
54_L 58_W 1.66 1.00
204_A 218_I 1.647 1.00
106_G 109_K 1.629 1.00
200_M 222_F 1.613 1.00
185_I 230_G 1.608 1.00
229_G 233_L 1.596 1.00
80_V 170_I 1.589 1.00
32_L 36_G 1.534 1.00
220_L 227_V 1.503 1.00
242_T 272_A 1.501 1.00
101_T 190_R 1.499 1.00
94_F 223_T 1.49 1.00
96_I 186_A 1.489 1.00
135_F 172_A 1.486 1.00
144_Q 147_V 1.453 1.00
86_L 231_I 1.441 1.00
193_F 219_V 1.424 1.00
59_T 286_A 1.41 1.00
189_M 230_G 1.41 1.00
192_V 223_T 1.406 0.99
108_L 111_P 1.398 0.99
113_G 190_R 1.396 0.99
283_H 286_A 1.38 0.99
100_L 186_A 1.366 0.99
36_G 40_S 1.366 0.99
170_I 264_G 1.365 0.99
94_F 227_V 1.361 0.99
251_N 255_L 1.356 0.99
196_T 222_F 1.345 0.99
85_A 238_A 1.337 0.99
81_T 266_S 1.336 0.99
78_T 268_T 1.329 0.99
80_V 84_I 1.324 0.99
79_L 83_F 1.314 0.99
249_I 264_G 1.312 0.99
185_I 234_G 1.312 0.99
201_K 205_Y 1.297 0.99
168_I 251_N 1.295 0.99
270_A 290_L 1.287 0.99
242_T 246_T 1.285 0.99
274_E 283_H 1.284 0.99
105_P 109_K 1.276 0.99
53_G 56_F 1.27 0.99
128_G 247_F 1.251 0.99
37_I 292_L 1.249 0.99
144_Q 160_L 1.235 0.98
57_L 292_L 1.23 0.98
146_P 151_M 1.226 0.98
59_T 283_H 1.209 0.98
89_A 234_G 1.204 0.98
244_A 248_I 1.202 0.98
91_P 95_G 1.198 0.98
222_F 225_N 1.196 0.98
107_W 110_R 1.192 0.98
84_I 88_I 1.189 0.98
156_I 160_L 1.178 0.98
182_I 186_A 1.176 0.98
40_S 288_M 1.172 0.98
198_V 201_K 1.172 0.98
100_L 112_L 1.165 0.97
87_L 91_P 1.164 0.97
210_T 214_V 1.159 0.97
215_I 220_L 1.154 0.97
171_L 175_V 1.153 0.97
111_P 115_A 1.152 0.97
83_F 87_L 1.151 0.97
145_E 149_N 1.145 0.97
196_T 223_T 1.144 0.97
270_A 274_E 1.134 0.97
78_T 267_I 1.131 0.97
307_F 310_M 1.126 0.97
102_E 198_V 1.122 0.97
209_C 214_V 1.121 0.97
84_I 87_L 1.119 0.96
71_A 290_L 1.118 0.96
166_F 171_L 1.114 0.96
251_N 264_G 1.113 0.96
170_I 174_G 1.107 0.96
254_Q 262_M 1.101 0.96
265_N 269_S 1.1 0.96
89_A 93_S 1.099 0.96
56_F 285_A 1.095 0.96
274_E 290_L 1.095 0.96
98_L 193_F 1.094 0.96
42_I 52_F 1.092 0.96
75_I 267_I 1.078 0.95
85_A 177_L 1.077 0.95
95_G 99_F 1.075 0.95
98_L 215_I 1.071 0.95
275_F 287_L 1.063 0.95
109_K 194_E 1.063 0.95
241_E 245_V 1.063 0.95
303_A 307_F 1.063 0.95
176_I 248_I 1.062 0.95
131_G 248_I 1.062 0.95
176_I 244_A 1.054 0.95
37_I 288_M 1.05 0.94
146_P 149_N 1.048 0.94
76_Y 79_L 1.046 0.94
224_K 228_I 1.034 0.94
44_S 47_P 1.033 0.94
36_G 39_V 1.032 0.94
252_T 255_L 1.022 0.93
173_A 245_V 1.017 0.93
266_S 269_S 1.012 0.93
274_E 278_A 1.005 0.93
216_W 220_L 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2onkC40.84951000.389Contact Map0.763
3d31C20.85581000.418Contact Map0.683
3rlfF10.94671000.42Contact Map0.635
3rlfG10.88091000.438Contact Map0.765
3tuiA40.661499.90.577Contact Map0.756
2kluA10.12544.80.963Contact Map0
2yl4A10.300930.966Contact Map0.262
2m20A20.1162.50.967Contact Map0.275
4gn0A40.17872.20.968Contact Map0.421
3hd7B20.12852.10.969Contact Map
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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