May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YIEF - Uncharacterized protein YieF
UniProt: P0AGE6 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11723
Length: 188 (183)
Sequences: 2424
Seq/Len: 13.25
YIEF
Paralog alert: 0.57 [within 20: 0.11] - ratio of genomes with paralogs
Cluster includes: SSUE YIEF
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
38_N 69_Q 4.294 1.00
6_Q 36_E 3.487 1.00
8_V 73_A 2.81 1.00
86_S 129_H 2.771 1.00
115_T 123_G 2.712 1.00
68_E 72_Q 2.637 1.00
9_T 24_A 2.547 1.00
111_V 139_A 2.466 1.00
61_A 65_A 2.391 1.00
157_D 160_T 2.365 1.00
87_V 133_I 2.312 1.00
24_A 79_V 2.286 1.00
157_D 162_E 2.277 1.00
7_V 75_G 2.142 1.00
78_I 111_V 2.116 1.00
92_K 96_D 2.108 1.00
134_L 139_A 2.087 1.00
11_L 21_G 2.079 1.00
64_E 68_E 2.05 1.00
166_Q 170_D 1.99 1.00
66_L 94_A 1.928 1.00
75_G 179_F 1.905 1.00
30_I 173_T 1.732 1.00
107_A 138_D 1.704 1.00
112_L 175_Q 1.684 1.00
65_A 69_Q 1.625 1.00
70_I 76_V 1.622 1.00
7_V 35_M 1.601 1.00
113_I 127_Q 1.595 1.00
20_N 116_S 1.585 1.00
70_I 98_L 1.583 1.00
80_T 130_L 1.564 1.00
25_R 28_P 1.558 1.00
6_Q 38_N 1.544 1.00
23_V 116_S 1.504 1.00
95_I 137_L 1.466 1.00
76_V 139_A 1.463 1.00
83_Y 89_G 1.421 1.00
129_H 132_Q 1.407 0.99
82_E 125_R 1.399 0.99
21_G 25_R 1.389 0.99
87_V 129_H 1.381 0.99
112_L 179_F 1.377 0.99
49_Y 93_N 1.369 0.99
63_V 97_W 1.361 0.99
89_G 96_D 1.348 0.99
42_S 45_D 1.345 0.99
62_T 65_A 1.307 0.99
27_L 114_Q 1.305 0.99
23_V 172_L 1.291 0.99
85_Y 125_R 1.28 0.99
6_Q 72_Q 1.276 0.99
169_L 173_T 1.26 0.99
68_E 71_R 1.251 0.99
86_S 133_I 1.244 0.98
9_T 79_V 1.242 0.98
14_L 89_G 1.235 0.98
35_M 180_G 1.209 0.98
61_A 64_E 1.182 0.98
17_G 22_M 1.175 0.98
21_G 42_S 1.163 0.97
28_P 39_A 1.157 0.97
29_K 162_E 1.154 0.97
168_T 171_H 1.144 0.97
48_L 93_N 1.141 0.97
20_N 79_V 1.135 0.97
38_N 73_A 1.127 0.97
142_M 179_F 1.121 0.97
11_L 24_A 1.119 0.96
9_T 37_V 1.11 0.96
46_I 94_A 1.105 0.96
27_L 77_V 1.101 0.96
27_L 172_L 1.093 0.96
111_V 134_L 1.079 0.95
7_V 183_I 1.077 0.95
78_I 134_L 1.072 0.95
151_V 154_N 1.056 0.95
76_V 106_L 1.031 0.94
9_T 39_A 1.028 0.94
113_I 134_L 1.015 0.93
9_T 28_P 1.012 0.93
9_T 77_V 1.008 0.93
19_F 152_I 1.007 0.93
75_G 183_I 1.001 0.92
84_N 100_R 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3svlA20.99471000.335Contact Map0.812
2fzvA40.96281000.353Contact Map0.831
4hs4A80.98941000.358Contact Map0.812
3u7rA20.96811000.366Contact Map0.852
1rttA10.9841000.369Contact Map0.768
2q62A80.95741000.379Contact Map0.86
3fvwA20.95211000.415Contact Map0.809
3gfsA120.90431000.441Contact Map0.859
4ltnA10.92021000.457Contact Map0.736
3k1yA60.925599.90.46Contact Map0.759
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 1.5433 seconds.