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OPENSEQ.org

RL17 - 50S ribosomal protein L17
UniProt: P0AG44 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10878
Length: 127 (120)
Sequences: 1260
Seq/Len: 10.50

RL17
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
30_R 72_D 3.006 1.00
32_E 78_K 2.907 1.00
44_L 113_I 2.771 1.00
8_R 43_E 2.702 1.00
38_L 111_A 2.614 1.00
16_H 23_N 2.387 1.00
29_V 48_V 2.251 1.00
33_I 114_E 2.239 1.00
52_I 115_L 2.229 1.00
25_A 48_V 2.212 1.00
95_T 113_I 1.963 1.00
20_M 24_M 1.919 1.00
61_A 65_L 1.873 1.00
96_R 114_E 1.828 1.00
35_K 112_Y 1.779 1.00
28_L 48_V 1.768 1.00
29_V 115_L 1.732 1.00
66_A 80_F 1.702 1.00
77_A 81_N 1.702 1.00
32_E 86_R 1.669 1.00
20_M 40_K 1.642 1.00
54_L 66_A 1.64 1.00
67_F 76_V 1.566 1.00
23_N 27_S 1.547 1.00
14_S 18_Q 1.529 1.00
25_A 51_L 1.509 1.00
26_G 75_I 1.503 1.00
38_L 99_K 1.49 1.00
65_L 69_R 1.464 1.00
36_T 41_A 1.461 1.00
102_F 107_N 1.457 1.00
90_R 116_V 1.444 1.00
16_H 20_M 1.436 1.00
25_A 47_V 1.413 1.00
97_I 111_A 1.411 1.00
59_S 62_N 1.375 0.99
33_I 112_Y 1.363 0.99
49_E 97_I 1.352 0.99
10_L 43_E 1.332 0.99
29_V 75_I 1.318 0.99
22_R 71_R 1.31 0.99
100_C 112_Y 1.306 0.99
63_R 80_F 1.283 0.99
78_K 82_E 1.281 0.99
12_R 17_R 1.257 0.99
57_T 62_N 1.256 0.99
58_D 62_N 1.23 0.98
51_L 79_L 1.223 0.98
45_R 97_I 1.205 0.98
24_M 27_S 1.203 0.98
9_Q 13_N 1.181 0.98
13_N 16_H 1.164 0.97
54_L 65_L 1.155 0.97
81_N 85_P 1.14 0.97
60_V 64_R 1.135 0.97
65_L 68_A 1.116 0.96
70_T 75_I 1.111 0.96
20_M 27_S 1.096 0.96
26_G 70_T 1.095 0.96
22_R 26_G 1.091 0.96
87_F 115_L 1.056 0.95
30_R 75_I 1.04 0.94
55_A 79_L 1.04 0.94
43_E 46_R 1.034 0.94
45_R 49_E 1.027 0.94
55_A 84_G 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kixN111000.008Contact Map0.812
3bboP10.91341000.044Contact Map0.671
1gd8A90.92131000.052Contact Map0.814
2zjrK10.91341000.058Contact Map0.712
3j3wN10.88191000.106Contact Map0.736
2cqmA10.90551000.146Contact Map0.626
2bkmA20.417312.60.945Contact Map0.226
1ux8A10.440910.30.947Contact Map0.248
3aq9A20.39377.50.95Contact Map0.187
4hzfA20.79536.40.952Contact Map0.208

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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