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OPENSEQ.org

YADS - UPF0126 inner membrane protein YadS
UniProt: P0AFP0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12333
Length: 207 (200)
Sequences: 1169
Seq/Len: 5.84

YADS
Paralog alert: 0.44 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YADS YICG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
102_V 154_C 3.22 1.00
25_L 140_E 2.879 1.00
53_H 108_K 2.863 1.00
35_L 138_A 2.52 1.00
36_G 72_S 2.357 1.00
12_A 71_T 2.354 1.00
157_G 183_T 2.272 1.00
184_L 188_L 2.242 1.00
45_T 58_W 2.173 1.00
110_F 119_A 2.034 1.00
96_V 184_L 2.022 1.00
99_A 184_L 2.007 1.00
189_A 193_W 1.959 1.00
14_F 97_G 1.826 1.00
98_L 127_G 1.824 1.00
92_V 188_L 1.82 1.00
140_E 146_R 1.747 1.00
38_V 137_L 1.743 1.00
45_T 129_G 1.722 1.00
30_F 151_A 1.69 1.00
106_V 158_G 1.668 1.00
11_T 14_F 1.618 0.99
27_M 138_A 1.617 0.99
91_P 191_I 1.571 0.99
7_D 64_D 1.564 0.99
160_V 182_V 1.561 0.99
189_A 195_L 1.553 0.99
53_H 112_A 1.494 0.99
10_G 14_F 1.487 0.99
71_T 75_T 1.487 0.99
124_V 155_I 1.466 0.99
103_G 183_T 1.46 0.99
33_L 72_S 1.434 0.98
95_A 184_L 1.412 0.98
190_A 195_L 1.411 0.98
21_L 138_A 1.41 0.98
102_V 106_V 1.407 0.98
106_V 162_A 1.369 0.98
109_A 122_M 1.368 0.98
62_P 66_V 1.356 0.98
98_L 154_C 1.356 0.98
58_W 129_G 1.345 0.97
99_A 103_G 1.339 0.97
181_V 185_L 1.334 0.97
35_L 139_R 1.329 0.97
40_A 68_A 1.328 0.97
132_I 137_L 1.328 0.97
4_Y 8_I 1.326 0.97
137_L 145_L 1.32 0.97
45_T 57_F 1.316 0.97
156_I 186_I 1.306 0.97
99_A 180_M 1.274 0.96
149_I 153_A 1.265 0.96
144_I 185_L 1.247 0.95
11_T 41_V 1.243 0.95
34_V 151_A 1.222 0.95
163_T 167_T 1.219 0.95
119_A 123_G 1.215 0.95
58_W 118_I 1.214 0.95
119_A 162_A 1.207 0.94
106_V 123_G 1.204 0.94
14_F 17_S 1.185 0.94
97_G 101_F 1.178 0.93
100_V 104_I 1.166 0.93
41_V 68_A 1.156 0.92
51_L 114_A 1.138 0.92
120_V 159_I 1.133 0.91
114_A 118_I 1.133 0.91
142_P 145_L 1.13 0.91
175_A 179_G 1.122 0.91
36_G 68_A 1.11 0.90
11_T 15_A 1.094 0.89
163_T 166_Y 1.093 0.89
13_V 97_G 1.088 0.89
46_I 125_I 1.082 0.89
45_T 50_A 1.078 0.88
120_V 155_I 1.072 0.88
56_V 59_V 1.07 0.88
37_V 68_A 1.069 0.88
37_V 65_L 1.068 0.88
23_G 32_V 1.068 0.88
99_A 157_G 1.067 0.88
30_F 34_V 1.065 0.88
104_I 126_T 1.058 0.87
106_V 119_A 1.057 0.87
101_F 187_R 1.047 0.86
46_I 133_I 1.043 0.86
111_N 174_T 1.043 0.86
153_A 186_I 1.043 0.86
180_M 184_L 1.04 0.86
128_V 144_I 1.034 0.86
6_L 100_V 1.031 0.85
123_G 179_G 1.026 0.85
101_F 145_L 1.025 0.85
107_N 161_H 1.023 0.85
50_A 59_V 1.015 0.84
45_T 56_V 1.011 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2f2bA10.41065.60.963Contact Map0.43
3llqA20.4012.50.969Contact Map0.497
3gd8A10.41061.80.971Contact Map0.436
2o9gA10.40581.70.972Contact Map0.441
1s4zC10.140110.975Contact Map0
2xutA30.874410.975Contact Map0.071
1vfgA20.439610.976Contact Map0.013
4bwzA10.898610.976Contact Map0.287
4b19A10.14490.80.977Contact Map0.021
3arcJ20.19320.80.977Contact Map0.402

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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