| UniProt: | P0AFK6 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10751 | ||
| Length: | 264 (253) | ||
| Sequences: | 23915 | ||
| Seq/Len: | 94.53 |
| POTC
Paralog alert: 0.96 [within 20: 0.87] - ratio of genomes with paralogs Cluster includes: CYST CYSW MALG MODB POTB POTC POTH POTI PSTA PSTC UGPA UGPE YCJO YCJP YDCU YDCV |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 171_T | 175_K | 4.501 | 1.00 | |
| 29_S | 47_Y | 3.8 | 1.00 | |
| 61_Q | 65_T | 3.336 | 1.00 | |
| 168_S | 171_T | 2.908 | 1.00 | |
| 170_F | 174_R | 2.817 | 1.00 | |
| 45_K | 48_S | 2.607 | 1.00 | |
| 148_Y | 152_K | 2.573 | 1.00 | |
| 159_L | 177_I | 2.553 | 1.00 | |
| 163_K | 172_I | 2.552 | 1.00 | |
| 45_K | 49_L | 2.517 | 1.00 | |
| 57_L | 61_Q | 2.387 | 1.00 | |
| 59_A | 217_K | 2.374 | 1.00 | |
| 58_Q | 61_Q | 2.355 | 1.00 | |
| 73_F | 136_I | 2.343 | 1.00 | |
| 87_R | 159_L | 2.319 | 1.00 | |
| 147_V | 185_V | 2.287 | 1.00 | |
| 169_E | 172_I | 2.245 | 1.00 | |
| 162_A | 172_I | 2.218 | 1.00 | |
| 79_S | 173_L | 2.212 | 1.00 | |
| 48_S | 52_N | 2.156 | 1.00 | |
| 71_A | 189_W | 2.154 | 1.00 | |
| 151_L | 181_A | 2.148 | 1.00 | |
| 69_F | 132_L | 2.096 | 1.00 | |
| 212_E | 220_S | 2.083 | 1.00 | |
| 167_A | 171_T | 2.027 | 1.00 | |
| 143_V | 188_G | 1.936 | 1.00 | |
| 171_T | 174_R | 1.936 | 1.00 | |
| 86_Y | 152_K | 1.914 | 1.00 | |
| 150_R | 184_A | 1.895 | 1.00 | |
| 90_F | 93_K | 1.841 | 1.00 | |
| 67_A | 193_F | 1.84 | 1.00 | |
| 163_K | 169_E | 1.816 | 1.00 | |
| 79_S | 181_A | 1.755 | 1.00 | |
| 75_T | 189_W | 1.752 | 1.00 | |
| 158_M | 180_L | 1.744 | 1.00 | |
| 162_A | 167_A | 1.714 | 1.00 | |
| 78_G | 143_V | 1.709 | 1.00 | |
| 65_T | 128_F | 1.703 | 1.00 | |
| 58_Q | 62_H | 1.698 | 1.00 | |
| 23_I | 27_V | 1.678 | 1.00 | |
| 159_L | 172_I | 1.676 | 1.00 | |
| 27_V | 31_N | 1.666 | 1.00 | |
| 65_T | 69_F | 1.646 | 1.00 | |
| 178_L | 185_V | 1.645 | 1.00 | |
| 200_V | 219_Y | 1.613 | 1.00 | |
| 127_G | 211_Y | 1.595 | 1.00 | |
| 79_S | 147_V | 1.572 | 1.00 | |
| 89_R | 93_K | 1.553 | 1.00 | |
| 44_T | 48_S | 1.542 | 1.00 | |
| 49_L | 229_E | 1.514 | 1.00 | |
| 70_S | 196_S | 1.492 | 1.00 | |
| 87_R | 156_V | 1.48 | 1.00 | |
| 43_T | 46_W | 1.469 | 1.00 | |
| 159_L | 163_K | 1.466 | 1.00 | |
| 168_S | 172_I | 1.462 | 1.00 | |
| 86_Y | 148_Y | 1.44 | 1.00 | |
| 82_A | 147_V | 1.433 | 1.00 | |
| 81_T | 144_V | 1.417 | 1.00 | |
| 128_F | 211_Y | 1.408 | 1.00 | |
| 26_I | 235_T | 1.367 | 0.99 | |
| 76_L | 80_L | 1.365 | 0.99 | |
| 187_A | 191_L | 1.364 | 0.99 | |
| 246_I | 250_L | 1.361 | 0.99 | |
| 119_F | 130_S | 1.357 | 0.99 | |
| 20_I | 24_I | 1.346 | 0.99 | |
| 60_A | 214_L | 1.343 | 0.99 | |
| 147_V | 188_G | 1.334 | 0.99 | |
| 162_A | 176_I | 1.334 | 0.99 | |
| 143_V | 192_S | 1.328 | 0.99 | |
| 156_V | 159_L | 1.322 | 0.99 | |
| 129_W | 133_F | 1.319 | 0.99 | |
| 92_G | 95_F | 1.319 | 0.99 | |
| 85_L | 144_V | 1.307 | 0.99 | |
| 200_V | 204_S | 1.293 | 0.99 | |
| 66_M | 213_I | 1.291 | 0.99 | |
| 47_Y | 235_T | 1.283 | 0.99 | |
| 64_L | 68_V | 1.259 | 0.99 | |
| 154_F | 180_L | 1.257 | 0.99 | |
| 226_V | 229_E | 1.24 | 0.98 | |
| 79_S | 185_V | 1.234 | 0.98 | |
| 157_R | 160_E | 1.23 | 0.98 | |
| 134_S | 206_V | 1.23 | 0.98 | |
| 63_S | 215_P | 1.229 | 0.98 | |
| 151_L | 177_I | 1.227 | 0.98 | |
| 126_L | 208_G | 1.219 | 0.98 | |
| 30_F | 42_F | 1.212 | 0.98 | |
| 24_I | 28_N | 1.207 | 0.98 | |
| 213_I | 216_L | 1.183 | 0.98 | |
| 62_H | 65_T | 1.175 | 0.98 | |
| 150_R | 181_A | 1.169 | 0.97 | |
| 49_L | 52_N | 1.166 | 0.97 | |
| 95_F | 99_M | 1.163 | 0.97 | |
| 173_L | 178_L | 1.159 | 0.97 | |
| 68_V | 72_T | 1.159 | 0.97 | |
| 167_A | 172_I | 1.154 | 0.97 | |
| 180_L | 183_P | 1.153 | 0.97 | |
| 74_A | 78_G | 1.149 | 0.97 | |
| 69_F | 72_T | 1.144 | 0.97 | |
| 74_A | 192_S | 1.138 | 0.97 | |
| 208_G | 211_Y | 1.133 | 0.97 | |
| 69_F | 73_F | 1.132 | 0.97 | |
| 65_T | 68_V | 1.118 | 0.96 | |
| 140_L | 144_V | 1.113 | 0.96 | |
| 70_S | 135_H | 1.106 | 0.96 | |
| 182_M | 254_D | 1.104 | 0.96 | |
| 80_L | 84_A | 1.1 | 0.96 | |
| 97_S | 148_Y | 1.084 | 0.96 | |
| 128_F | 132_L | 1.083 | 0.96 | |
| 217_K | 221_M | 1.082 | 0.96 | |
| 221_M | 224_V | 1.066 | 0.95 | |
| 83_V | 151_L | 1.066 | 0.95 | |
| 147_V | 184_A | 1.064 | 0.95 | |
| 182_M | 185_V | 1.063 | 0.95 | |
| 73_F | 132_L | 1.062 | 0.95 | |
| 159_L | 169_E | 1.061 | 0.95 | |
| 202_V | 206_V | 1.061 | 0.95 | |
| 50_L | 236_I | 1.06 | 0.95 | |
| 55_S | 58_Q | 1.052 | 0.95 | |
| 203_S | 213_I | 1.051 | 0.94 | |
| 135_H | 196_S | 1.05 | 0.94 | |
| 67_A | 71_A | 1.043 | 0.94 | |
| 174_R | 178_L | 1.04 | 0.94 | |
| 95_F | 98_G | 1.04 | 0.94 | |
| 250_L | 254_D | 1.034 | 0.94 | |
| 49_L | 53_N | 1.029 | 0.94 | |
| 154_F | 181_A | 1.021 | 0.93 | |
| 61_Q | 64_L | 1.019 | 0.93 | |
| 72_T | 76_L | 1.016 | 0.93 | |
| 199_D | 203_S | 1.008 | 0.93 | |
| 83_V | 173_L | 1.003 | 0.93 | |
| 51_M | 57_L | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2onkC | 4 | 0.9432 | 100 | 0.329 | Contact Map | 0.753 |
| 3rlfG | 1 | 0.9848 | 100 | 0.336 | Contact Map | 0.756 |
| 3d31C | 2 | 0.947 | 100 | 0.357 | Contact Map | 0.671 |
| 3rlfF | 1 | 0.9735 | 100 | 0.389 | Contact Map | 0.642 |
| 3tuiA | 4 | 0.7841 | 99.9 | 0.534 | Contact Map | 0.745 |
| 4b19A | 1 | 0.1136 | 3.3 | 0.961 | Contact Map | 0.509 |
| 2kv5A | 1 | 0.125 | 2.3 | 0.964 | Contact Map | 0.473 |
| 3ne5A | 1 | 0.2652 | 1.7 | 0.966 | Contact Map | 0.547 |
| 4dxwA | 4 | 0.3561 | 1.4 | 0.968 | Contact Map | 0.463 |
| 4gn0A | 4 | 0.2121 | 1.3 | 0.968 | Contact Map | 0.636 |
Sequence Conservation (Image Generated using WebLogo v3)