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OPENSEQ.org
MOG - Molybdopterin adenylyltransferase
UniProt: P0AF03 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11511
Length: 195 (176)
Sequences: 1022
Seq/Len: 5.81
MOG
Paralog alert: 0.04 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: MOAB MOG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
89_L 95_E 3.867 1.00
101_E 104_R 3.349 1.00
106_I 109_H 2.963 1.00
13_D 81_R 2.941 1.00
88_T 131_N 2.827 1.00
92_A 122_V 2.656 1.00
93_D 125_K 2.264 1.00
9_V 61_L 2.197 1.00
51_Q 55_E 2.083 1.00
137_K 141_E 2.039 1.00
11_I 54_I 2.03 1.00
15_A 20_Y 2.03 1.00
78_P 96_M 1.966 1.00
51_Q 90_A 1.825 1.00
11_I 47_I 1.768 1.00
94_R 123_I 1.745 1.00
124_R 129_I 1.724 1.00
6_I 32_L 1.723 1.00
14_R 20_Y 1.69 1.00
63_D 124_R 1.671 1.00
55_E 90_A 1.668 1.00
45_R 60_E 1.634 1.00
80_R 126_Q 1.622 0.99
103_M 142_T 1.607 0.99
62_V 70_V 1.607 0.99
95_E 100_G 1.596 0.99
29_E 44_T 1.594 0.99
102_Q 105_Q 1.568 0.99
50_E 53_I 1.546 0.99
31_W 144_E 1.543 0.99
54_I 83_V 1.541 0.99
24_G 73_T 1.508 0.99
50_E 83_V 1.497 0.99
92_A 120_V 1.485 0.99
7_G 67_C 1.474 0.99
57_T 60_E 1.461 0.99
50_E 54_I 1.451 0.99
100_G 121_G 1.451 0.99
178_P 182_A 1.446 0.99
51_Q 83_V 1.44 0.98
26_P 44_T 1.416 0.98
123_I 169_L 1.407 0.98
9_V 54_I 1.389 0.98
28_L 139_I 1.38 0.98
100_G 104_R 1.372 0.98
72_T 131_N 1.358 0.98
10_S 73_T 1.357 0.98
7_G 61_L 1.353 0.97
98_G 104_R 1.34 0.97
54_I 58_L 1.31 0.97
47_I 57_T 1.284 0.96
58_L 131_N 1.281 0.96
29_E 33_T 1.28 0.96
130_L 162_V 1.279 0.96
9_V 58_L 1.277 0.96
92_A 95_E 1.27 0.96
57_T 61_L 1.27 0.96
28_L 143_L 1.27 0.96
58_L 88_T 1.265 0.96
30_E 34_S 1.264 0.96
176_T 183_A 1.24 0.95
89_L 120_V 1.223 0.95
96_M 100_G 1.184 0.93
132_L 143_L 1.172 0.93
130_L 146_V 1.17 0.93
23_K 136_P 1.169 0.93
45_R 57_T 1.155 0.92
4_L 166_I 1.146 0.92
166_I 171_G 1.141 0.92
24_G 139_I 1.127 0.91
107_S 114_A 1.126 0.91
10_S 24_G 1.115 0.90
47_I 54_I 1.106 0.90
110_F 141_E 1.103 0.90
71_L 132_L 1.093 0.89
53_I 57_T 1.088 0.89
36_L 174_V 1.087 0.89
55_E 87_A 1.086 0.89
110_F 137_K 1.084 0.89
85_P 131_N 1.076 0.88
55_E 91_V 1.066 0.88
62_V 124_R 1.065 0.88
38_T 42_L 1.064 0.87
12_S 49_D 1.061 0.87
73_T 139_I 1.052 0.87
99_F 115_I 1.049 0.86
103_M 146_V 1.047 0.86
61_L 67_C 1.045 0.86
9_V 57_T 1.043 0.86
52_A 55_E 1.041 0.86
60_E 64_E 1.035 0.85
75_G 84_T 1.024 0.85
68_H 170_E 1.015 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1di6A111000.342Contact Map0.787
2pbqA30.90261000.436Contact Map0.865
2is8A30.8411000.503Contact Map0.81
2g2cA10.80511000.51Contact Map0.708
3pzyA10.82051000.515Contact Map0.658
1jljA30.89741000.519Contact Map0.892
3rfqA30.80511000.519Contact Map0.768
1uuyA10.82051000.523Contact Map0.756
4lhbA30.78971000.529Contact Map0.814
2pjkA30.80511000.53Contact Map0.768
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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