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RL16 - 50S ribosomal protein L16
UniProt: P0ADY7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10877
Length: 136 (135)
Sequences: 1081
Seq/Len: 8.01

RL16
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
26_V 32_G 3.518 1.00
110_E 114_R 3.179 1.00
117_F 130_F 2.903 1.00
35_A 126_I 2.698 1.00
109_P 112_L 2.591 1.00
115_E 118_K 2.361 1.00
30_S 106_D 2.321 1.00
41_L 67_V 2.249 1.00
57_V 105_M 2.233 1.00
73_I 91_Y 2.221 1.00
121_A 128_T 2.188 1.00
53_M 63_I 2.096 1.00
110_E 132_T 2.052 1.00
40_R 95_L 2.037 1.00
37_G 127_K 1.965 1.00
49_A 124_L 1.964 1.00
71_K 95_L 1.84 1.00
41_L 126_I 1.831 1.00
31_F 130_F 1.796 1.00
15_G 71_K 1.773 1.00
28_F 66_R 1.731 1.00
32_G 131_V 1.639 1.00
53_M 105_M 1.631 1.00
56_A 112_L 1.63 1.00
33_L 121_A 1.591 1.00
114_R 130_F 1.522 1.00
34_K 131_V 1.486 0.99
49_A 103_Y 1.481 0.99
42_T 45_Q 1.473 0.99
63_I 105_M 1.467 0.99
34_K 129_T 1.464 0.99
3_Q 43_A 1.449 0.99
41_L 102_L 1.433 0.99
75_E 90_E 1.386 0.99
57_V 112_L 1.355 0.99
76_K 80_V 1.353 0.99
74_T 89_V 1.334 0.99
12_M 72_P 1.314 0.98
53_M 120_A 1.27 0.98
54_T 63_I 1.254 0.98
7_T 12_M 1.25 0.98
57_V 60_Q 1.231 0.97
32_G 101_V 1.227 0.97
14_K 40_R 1.223 0.97
43_A 91_Y 1.2 0.97
81_R 92_W 1.198 0.97
73_I 95_L 1.179 0.96
21_A 100_K 1.172 0.96
101_V 131_V 1.166 0.96
118_K 122_A 1.15 0.96
23_G 27_S 1.129 0.95
67_V 126_I 1.126 0.95
28_F 44_R 1.121 0.95
67_V 102_L 1.113 0.94
17_N 38_R 1.106 0.94
7_T 92_W 1.101 0.94
30_S 133_K 1.092 0.94
47_E 50_R 1.072 0.93
56_A 115_E 1.067 0.93
26_V 131_V 1.056 0.92
5_K 92_W 1.053 0.92
27_S 66_R 1.052 0.92
77_P 80_V 1.045 0.92
103_Y 124_L 1.038 0.91
40_R 129_T 1.035 0.91
55_R 116_A 1.032 0.91
17_N 71_K 1.023 0.90
9_F 12_M 1.021 0.90
15_G 73_I 1.017 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2zjrJ111000.095Contact Map0.66
3bboO10.98531000.098Contact Map0.565
4kixM111000.108Contact Map0.709
2ftcI10.83821000.265Contact Map0.002
1ffkF10.98531000.331Contact Map0.091
2pa2A20.86761000.342Contact Map0.652
1vq8H111000.345Contact Map0.634
3j3bI10.99261000.35Contact Map0.543
4a17H111000.35Contact Map0.498
3j0lJ111000.351Contact Map0.203

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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