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OPENSEQ.org
LPTC - Lipopolysaccharide export system protein LptC
UniProt: P0ADV9 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12806
Length: 191 (186)
Sequences: 372
Seq/Len: 2.00
LPTC
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
99_D 114_H 5.506 1.00
115_V 131_T 2.489 1.00
145_S 162_K 2.368 1.00
65_Q 80_Q 2.223 1.00
98_A 111_L 2.061 0.99
64_A 78_F 2.041 0.99
94_W 167_L 2.034 0.99
101_A 104_T 1.985 0.99
82_V 160_G 1.88 0.98
153_G 156_F 1.765 0.97
133_N 147_D 1.738 0.97
103_L 109_L 1.702 0.96
50_L 58_L 1.674 0.96
15_A 79_T 1.609 0.94
164_R 173_E 1.604 0.94
41_T 69_Y 1.568 0.93
99_D 132_D 1.539 0.92
48_D 171_N 1.526 0.92
47_T 64_A 1.486 0.91
80_Q 99_D 1.478 0.90
166_N 169_S 1.47 0.90
153_G 160_G 1.467 0.90
101_A 111_L 1.457 0.89
70_Y 181_S 1.455 0.89
78_F 103_L 1.412 0.87
96_V 117_V 1.405 0.87
51_V 101_A 1.373 0.85
62_L 78_F 1.367 0.85
160_G 172_A 1.348 0.84
11_V 31_A 1.344 0.84
97_K 118_N 1.34 0.83
68_E 77_W 1.332 0.83
178_V 183_E 1.324 0.82
45_E 66_H 1.3 0.81
9_I 79_T 1.284 0.80
67_V 182_Y 1.282 0.79
174_L 180_T 1.266 0.78
153_G 182_Y 1.265 0.78
94_W 165_G 1.257 0.78
114_H 132_D 1.257 0.78
16_V 22_I 1.236 0.76
99_D 113_G 1.218 0.74
38_N 72_D 1.208 0.74
9_I 13_S 1.206 0.73
162_K 176_E 1.187 0.72
9_I 117_V 1.172 0.70
43_K 180_T 1.157 0.69
154_T 182_Y 1.153 0.68
22_I 97_K 1.149 0.68
113_G 132_D 1.149 0.68
172_A 179_R 1.142 0.67
119_A 127_R 1.14 0.67
131_T 145_S 1.13 0.66
94_W 182_Y 1.124 0.66
27_K 101_A 1.107 0.64
53_N 66_H 1.104 0.64
145_S 176_E 1.1 0.63
10_I 26_E 1.1 0.63
77_W 102_K 1.096 0.63
45_E 57_A 1.095 0.63
22_I 171_N 1.087 0.62
57_A 160_G 1.075 0.61
62_L 170_K 1.072 0.60
134_A 161_L 1.067 0.60
142_D 166_N 1.056 0.58
44_S 160_G 1.056 0.58
10_I 14_L 1.054 0.58
107_R 119_A 1.053 0.58
35_V 67_V 1.049 0.58
23_N 47_T 1.035 0.56
15_A 80_Q 1.033 0.56
86_F 129_I 1.026 0.55
158_S 180_T 1.024 0.55
42_Y 106_D 1.02 0.55
47_T 78_F 1.019 0.54
120_L 153_G 1.013 0.54
53_N 95_S 1.01 0.53
14_L 18_V 1.009 0.53
94_W 154_T 1.009 0.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3my2A10.89011000.415Contact Map0.527
2r19A20.71298.40.807Contact Map0.454
3ne5B20.916215.90.944Contact Map0.012
2v2fA10.12577.50.952Contact Map1
2mc7A10.12575.10.955Contact Map0.369
2lcnA10.109950.956Contact Map0.085
3o0lA20.49744.40.957Contact Map0.078
2lcoA10.10994.40.957Contact Map0.001
2kv5A10.16233.40.959Contact Map0.014
3hunA20.81152.90.961Contact Map0.237
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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