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OPENSEQ.org
YGIM - Uncharacterized protein YgiM
UniProt: P0ADT8 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12434
Length: 206 (206)
Sequences: 244
Seq/Len: 1.18
YGIM
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
174_F 180_V 2.463 0.99
56_V 70_V 2.462 0.99
60_Q 69_Q 2.346 0.99
189_L 192_P 2.298 0.99
101_Q 106_T 2.189 0.98
68_A 82_L 2.057 0.97
184_G 192_P 1.937 0.96
28_V 70_V 1.934 0.96
148_L 151_A 1.816 0.94
35_W 46_L 1.693 0.90
28_V 80_I 1.692 0.90
173_W 180_V 1.633 0.88
56_V 85_L 1.622 0.87
41_G 44_Y 1.613 0.87
59_L 71_K 1.595 0.86
141_N 144_L 1.562 0.84
91_L 95_V 1.549 0.84
52_A 72_D 1.528 0.83
13_A 16_A 1.512 0.82
94_R 99_E 1.472 0.79
2_P 5_R 1.462 0.79
72_D 76_R 1.443 0.77
100_N 110_T 1.414 0.75
5_R 19_V 1.41 0.75
147_E 152_Q 1.395 0.74
39_G 44_Y 1.374 0.72
7_I 65_T 1.368 0.72
176_Y 192_P 1.368 0.72
175_M 179_G 1.362 0.71
29_S 40_P 1.356 0.71
102_V 105_L 1.317 0.68
127_V 130_S 1.286 0.65
50_V 200_R 1.282 0.65
2_P 16_A 1.281 0.64
94_R 191_L 1.281 0.64
69_Q 77_T 1.266 0.63
173_W 188_G 1.264 0.63
28_V 86_S 1.26 0.63
37_R 46_L 1.25 0.62
161_Q 165_K 1.247 0.61
36_V 80_I 1.24 0.61
56_V 132_S 1.239 0.61
7_I 10_T 1.238 0.61
9_L 16_A 1.233 0.60
50_V 105_L 1.226 0.59
37_R 71_K 1.221 0.59
97_D 190_V 1.217 0.59
79_W 141_N 1.216 0.58
143_K 147_E 1.211 0.58
58_L 174_F 1.211 0.58
67_Y 90_S 1.199 0.57
39_G 45_R 1.196 0.57
132_S 186_L 1.192 0.56
8_G 13_A 1.191 0.56
147_E 181_L 1.187 0.56
156_D 160_V 1.18 0.55
98_L 147_E 1.179 0.55
96_P 178_G 1.173 0.54
25_T 55_E 1.158 0.53
192_P 204_W 1.155 0.53
162_L 165_K 1.154 0.53
102_V 106_T 1.148 0.52
24_E 111_N 1.137 0.51
106_T 154_K 1.135 0.51
44_Y 68_A 1.115 0.49
56_V 148_L 1.113 0.49
126_K 130_S 1.111 0.48
132_S 198_R 1.107 0.48
43_H 46_L 1.107 0.48
24_E 101_Q 1.105 0.48
58_L 68_A 1.104 0.48
35_W 49_T 1.102 0.48
39_G 46_L 1.1 0.47
10_T 14_L 1.097 0.47
25_T 28_V 1.095 0.47
2_P 7_I 1.093 0.47
48_G 52_A 1.091 0.46
2_P 19_V 1.084 0.46
28_V 78_A 1.08 0.45
66_N 123_M 1.072 0.45
42_D 171_M 1.07 0.44
196_P 205_M 1.068 0.44
200_R 203_R 1.065 0.44
40_P 79_W 1.063 0.44
10_T 18_A 1.062 0.44
70_V 87_T 1.056 0.43
61_T 143_K 1.051 0.43
55_E 92_R 1.048 0.42
2_P 17_T 1.041 0.42
30_D 91_L 1.037 0.41
20_S 115_T 1.034 0.41
67_Y 98_L 1.027 0.40
140_E 189_L 1.025 0.40
20_S 186_L 1.024 0.40
5_R 78_A 1.021 0.40
8_G 18_A 1.017 0.39
191_L 197_S 1.017 0.39
118_Q 190_V 1.015 0.39
30_D 45_R 1.01 0.39
18_A 61_T 1.005 0.38
174_F 193_H 1.004 0.38
7_I 12_L 1.004 0.38
2_P 8_G 1.003 0.38
31_E 67_Y 1 0.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2kt8A10.368999.10.795Contact Map0.487
2kq8A10.3398990.803Contact Map0.313
2krsA10.3592990.803Contact Map0.44
3npfA20.733980.856Contact Map0.564
3h41A10.771897.50.872Contact Map0.391
1v1cA10.296194.60.903Contact Map0.69
3m1uA20.80194.60.903Contact Map0.419
2drmA40.23392.60.911Contact Map0.763
2hbwA10.708792.60.911Contact Map0.412
4hvuA10.242792.20.912Contact Map0.811
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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