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OPENSEQ.org
YIGP - Uncharacterized protein YigP
UniProt: P0ADP7 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11474
Length: 201 (201)
Sequences: 340
Seq/Len: 1.69
YIGP
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
127_T 131_A 3.315 1.00
120_A 133_E 2.435 1.00
189_D 192_T 2.316 1.00
185_E 190_A 2.227 0.99
21_R 119_P 2.006 0.99
71_V 105_V 1.87 0.97
166_R 173_E 1.865 0.97
65_G 98_V 1.63 0.93
80_K 95_E 1.582 0.92
121_E 124_A 1.58 0.91
177_F 181_T 1.575 0.91
69_C 105_V 1.544 0.90
186_R 189_D 1.503 0.89
182_A 185_E 1.488 0.88
35_K 159_E 1.466 0.87
121_E 129_D 1.457 0.86
161_I 168_A 1.444 0.86
188_V 192_T 1.416 0.84
73_A 78_L 1.402 0.83
166_R 170_G 1.399 0.83
197_K 201_K 1.375 0.82
131_A 150_I 1.37 0.81
108_F 112_A 1.357 0.81
136_S 140_R 1.356 0.80
22_S 193_K 1.344 0.80
37_L 74_Y 1.339 0.79
147_H 195_L 1.336 0.79
119_P 122_L 1.321 0.78
158_A 171_P 1.321 0.78
163_E 170_G 1.319 0.78
15_L 52_F 1.303 0.77
190_A 193_K 1.292 0.76
71_V 127_T 1.288 0.75
24_A 187_A 1.281 0.75
169_P 173_E 1.274 0.74
88_T 91_I 1.273 0.74
8_T 59_V 1.272 0.74
17_T 57_V 1.262 0.73
37_L 108_F 1.257 0.73
117_F 122_L 1.252 0.73
80_K 83_D 1.249 0.72
186_R 190_A 1.246 0.72
155_R 159_E 1.239 0.71
7_V 39_V 1.231 0.71
14_L 174_V 1.22 0.70
67_A 126_Y 1.211 0.69
50_L 57_V 1.201 0.68
130_I 192_T 1.2 0.68
79_P 88_T 1.172 0.65
40_E 72_I 1.168 0.65
96_L 183_A 1.166 0.65
33_L 117_F 1.165 0.65
18_F 73_A 1.156 0.64
22_S 117_F 1.15 0.63
71_V 162_T 1.143 0.62
43_G 75_A 1.143 0.62
35_K 101_D 1.141 0.62
30_S 135_I 1.133 0.61
74_Y 135_I 1.122 0.60
116_E 119_P 1.122 0.60
33_L 99_Q 1.12 0.60
17_T 122_L 1.118 0.60
1_M 6_L 1.117 0.60
19_L 158_A 1.11 0.59
133_E 161_I 1.108 0.59
27_T 144_K 1.101 0.58
192_T 196_E 1.097 0.58
178_A 181_T 1.092 0.57
161_I 167_M 1.089 0.57
86_Q 94_G 1.081 0.56
53_S 58_D 1.078 0.56
25_L 115_A 1.077 0.56
15_L 59_V 1.076 0.55
156_Y 159_E 1.073 0.55
37_L 104_V 1.069 0.55
49_I 104_V 1.068 0.55
36_V 63_W 1.066 0.54
50_L 144_K 1.063 0.54
159_E 169_P 1.056 0.53
196_E 201_K 1.054 0.53
15_L 98_V 1.052 0.53
3_F 6_L 1.045 0.52
45_S 72_I 1.044 0.52
50_L 54_E 1.042 0.52
174_V 181_T 1.041 0.52
135_I 173_E 1.037 0.51
15_L 101_D 1.03 0.51
9_A 12_E 1.023 0.50
73_A 98_V 1.023 0.50
35_K 68_D 1.021 0.50
43_G 103_Q 1.017 0.49
52_F 172_L 1.014 0.49
131_A 135_I 1.011 0.49
163_E 184_V 1.008 0.48
102_I 174_V 1.007 0.48
69_C 90_L 1.002 0.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3cnuA10.567299.10.781Contact Map0.194
2qztA20.507598.50.82Contact Map0.426
1iktA10.552298.40.826Contact Map0.484
1pz4A10.517498.40.826Contact Map0.455
1c44A10.557298.20.832Contact Map0.344
2cx7A20.59298.10.838Contact Map0.294
2yheA60.572197.80.851Contact Map0.499
2cfuA10.582197.70.853Contact Map0.504
3bkrA10.532396.50.878Contact Map0.498
2yy0A40.228956.60.932Contact Map0.529
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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