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OPENSEQ.org

YIGI - Uncharacterized protein YigI
UniProt: P0ADP2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11467
Length: 155 (138)
Sequences: 2376
Seq/Len: 17.22

YIGI
Paralog alert: 0.62 [within 20: 0.06] - ratio of genomes with paralogs
Cluster includes: ENTH PAAI YDII YIGI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
102_I 130_V 3.515 1.00
33_E 43_A 3.218 1.00
43_A 116_R 3.038 1.00
41_Q 120_T 2.887 1.00
31_E 43_A 2.605 1.00
34_R 41_Q 2.58 1.00
120_T 138_H 2.52 1.00
34_R 39_F 2.47 1.00
42_L 71_A 2.456 1.00
44_F 63_V 2.227 1.00
36_E 39_F 2.191 1.00
71_A 119_A 2.056 1.00
139_N 143_L 1.988 1.00
136_E 144_Y 1.92 1.00
39_F 122_S 1.913 1.00
76_C 131_A 1.851 1.00
110_R 143_L 1.847 1.00
72_A 135_V 1.82 1.00
65_A 104_L 1.791 1.00
65_A 108_Y 1.681 1.00
43_A 118_T 1.677 1.00
68_L 148_A 1.668 1.00
112_G 145_I 1.615 1.00
122_S 134_R 1.593 1.00
39_F 120_T 1.578 1.00
68_L 135_V 1.573 1.00
38_E 78_G 1.537 1.00
65_A 106_V 1.507 1.00
24_F 63_V 1.49 1.00
72_A 150_A 1.469 1.00
8_E 12_K 1.431 1.00
119_A 135_V 1.425 1.00
45_K 116_R 1.412 1.00
6_T 9_Q 1.403 0.99
27_A 49_M 1.395 0.99
103_D 107_D 1.39 0.99
64_I 146_A 1.387 0.99
122_S 136_E 1.367 0.99
106_V 146_A 1.348 0.99
41_Q 118_T 1.341 0.99
125_R 130_V 1.33 0.99
46_N 59_L 1.329 0.99
117_F 137_L 1.319 0.99
79_S 126_A 1.317 0.99
134_R 147_S 1.311 0.99
134_R 149_T 1.302 0.99
12_K 16_E 1.3 0.99
31_E 45_K 1.283 0.99
47_Q 50_M 1.283 0.99
123_L 126_A 1.276 0.99
69_D 101_T 1.275 0.99
109_L 125_R 1.232 0.98
68_L 137_L 1.23 0.98
138_H 142_Q 1.228 0.98
62_G 66_S 1.218 0.98
76_C 152_Y 1.199 0.98
124_L 147_S 1.188 0.98
33_E 41_Q 1.152 0.97
136_E 147_S 1.114 0.96
110_R 125_R 1.097 0.96
129_K 153_M 1.091 0.96
64_I 145_I 1.072 0.95
115_E 140_E 1.065 0.95
109_L 144_Y 1.063 0.95
24_F 66_S 1.045 0.94
124_L 134_R 1.039 0.94
37_K 79_S 1.027 0.94
109_L 147_S 1.016 0.93
107_D 132_V 1.007 0.93
117_F 145_I 1.006 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3e8pA40.993599.90.288Contact Map0.804
3hduA3199.90.308Contact Map0.75
3f1tA40.883999.90.317Contact Map0.768
1yocA20.896899.90.339Contact Map0.659
3lmbA20.909799.90.34Contact Map0.683
1sh8A20.858199.90.343Contact Map0.713
1t82A40.864599.90.356Contact Map0.625
3gekA40.767799.90.359Contact Map0.851
1vh5A20.890399.90.364Contact Map0.842
1vh9A20.890399.90.364Contact Map0.744

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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