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OPENSEQ.org

YPHA - Inner membrane protein YphA
UniProt: P0AD47 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13462
Length: 140 (131)
Sequences: 1660
Seq/Len: 12.67

YPHA
Paralog alert: 0.42 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: YPHA YQJF
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_F 115_W 2.153 1.00
71_L 81_L 2.062 1.00
29_I 73_V 1.996 1.00
136_S 139_R 1.995 1.00
132_P 136_S 1.99 1.00
45_Y 48_S 1.99 1.00
28_F 85_F 1.953 1.00
35_K 65_E 1.901 1.00
85_F 124_F 1.869 1.00
68_A 81_L 1.792 1.00
126_L 130_T 1.772 1.00
93_A 121_A 1.761 1.00
25_V 69_A 1.753 1.00
77_F 80_P 1.715 1.00
20_A 126_L 1.705 1.00
70_I 74_L 1.696 1.00
17_L 130_T 1.682 1.00
27_I 120_I 1.612 1.00
127_L 130_T 1.588 1.00
24_V 123_A 1.579 1.00
109_P 113_N 1.56 1.00
86_I 121_A 1.548 1.00
36_M 62_V 1.546 1.00
39_F 62_V 1.544 1.00
42_T 46_M 1.527 1.00
23_A 122_G 1.517 1.00
14_P 134_A 1.509 1.00
33_F 66_V 1.497 1.00
25_V 73_V 1.496 1.00
83_V 128_A 1.467 1.00
89_T 92_T 1.467 1.00
18_L 22_I 1.401 0.99
114_F 118_V 1.391 0.99
16_L 129_I 1.382 0.99
80_P 84_L 1.381 0.99
39_F 59_I 1.38 0.99
116_K 120_I 1.347 0.99
97_H 117_N 1.285 0.99
61_A 64_M 1.26 0.99
35_K 61_A 1.251 0.99
125_L 129_I 1.248 0.99
76_F 138_D 1.232 0.98
18_L 135_I 1.207 0.98
45_Y 49_L 1.205 0.98
90_L 94_V 1.194 0.98
26_L 73_V 1.191 0.98
78_T 132_P 1.168 0.97
27_I 119_S 1.15 0.97
113_N 116_K 1.148 0.97
132_P 138_D 1.133 0.97
22_I 73_V 1.12 0.96
18_L 134_A 1.119 0.96
20_A 123_A 1.119 0.96
94_V 98_H 1.113 0.96
58_A 62_V 1.102 0.96
81_L 84_L 1.101 0.96
53_M 56_L 1.097 0.96
59_I 63_V 1.095 0.96
105_D 108_G 1.094 0.96
25_V 29_I 1.093 0.96
15_V 135_I 1.085 0.96
27_I 30_I 1.081 0.95
29_I 33_F 1.073 0.95
29_I 69_A 1.066 0.95
76_F 137_L 1.055 0.95
79_R 131_G 1.043 0.94
16_L 126_L 1.026 0.94
46_M 49_L 1.023 0.93
61_A 88_Y 1.022 0.93
74_L 137_L 1.018 0.93
41_G 45_Y 1.017 0.93
51_A 57_A 1.016 0.93
93_A 117_N 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3j27A30.58572.10.945Contact Map0.043
4cbfA20.585720.945Contact Map0.006
4azxA30.585720.945Contact Map0.014
3ldzA40.37861.40.95Contact Map0.792
2lonA10.34290.80.957Contact Map0.355
2lzrA10.21430.80.958Contact Map0.466
1xkpB10.30.70.958Contact Map0.005
2l16A10.22140.70.959Contact Map0.55
3arcI20.25710.70.959Contact Map0.286
2lomA10.33570.60.961Contact Map0.284

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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