| UniProt: | P0AD01 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12464 | ||
| Length: | 239 (202) | ||
| Sequences: | 12642 | ||
| Seq/Len: | 62.58 |
| DCUR
Paralog alert: 0.84 [within 20: 0.18] - ratio of genomes with paralogs Cluster includes: ARCA BAER BASR BGLJ CPXR CREB CSGD CUSR DCUR DPIA EVGA FIMZ KDPE NARL NARP OMPR PHOB PHOP QSEB RCSB RSTA TORR UHPA UVRY YEDW YGEK YHJB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 14_A | 32_T | 3.175 | 1.00 | |
| 7_I | 39_A | 2.942 | 1.00 | |
| 35_T | 61_K | 2.856 | 1.00 | |
| 18_R | 32_T | 2.763 | 1.00 | |
| 37_E | 61_K | 2.729 | 1.00 | |
| 35_T | 38_K | 2.531 | 1.00 | |
| 45_N | 74_A | 2.384 | 1.00 | |
| 179_F | 187_E | 2.369 | 1.00 | |
| 36_L | 62_E | 2.332 | 1.00 | |
| 34_S | 38_K | 2.272 | 1.00 | |
| 63_N | 66_D | 2.264 | 1.00 | |
| 82_V | 95_S | 2.242 | 1.00 | |
| 14_A | 34_S | 2.193 | 1.00 | |
| 3_N | 28_Q | 2.147 | 1.00 | |
| 62_E | 70_V | 2.107 | 1.00 | |
| 26_G | 118_T | 2.099 | 1.00 | |
| 81_I | 120_W | 2.055 | 1.00 | |
| 181_T | 196_R | 2.045 | 1.00 | |
| 55_L | 67_L | 2.015 | 1.00 | |
| 18_R | 22_A | 1.975 | 1.00 | |
| 198_Y | 201_W | 1.851 | 1.00 | |
| 55_L | 68_L | 1.842 | 1.00 | |
| 47_D | 50_I | 1.841 | 1.00 | |
| 33_A | 42_I | 1.812 | 1.00 | |
| 72_H | 101_V | 1.809 | 1.00 | |
| 20_Y | 110_A | 1.722 | 1.00 | |
| 21_V | 117_L | 1.711 | 1.00 | |
| 68_L | 80_V | 1.694 | 1.00 | |
| 57_I | 82_V | 1.69 | 1.00 | |
| 40_K | 70_V | 1.689 | 1.00 | |
| 42_I | 47_D | 1.689 | 1.00 | |
| 42_I | 46_S | 1.681 | 1.00 | |
| 162_Q | 166_T | 1.667 | 1.00 | |
| 119_G | 124_K | 1.634 | 1.00 | |
| 75_R | 78_S | 1.601 | 1.00 | |
| 31_G | 47_D | 1.554 | 1.00 | |
| 86_A | 91_T | 1.521 | 1.00 | |
| 5_L | 42_I | 1.515 | 1.00 | |
| 193_V | 196_R | 1.496 | 1.00 | |
| 190_I | 195_C | 1.465 | 1.00 | |
| 58_Y | 86_A | 1.462 | 1.00 | |
| 68_L | 82_V | 1.457 | 1.00 | |
| 52_L | 117_L | 1.453 | 1.00 | |
| 62_E | 66_D | 1.439 | 1.00 | |
| 24_I | 114_E | 1.433 | 1.00 | |
| 70_V | 74_A | 1.417 | 1.00 | |
| 5_L | 33_A | 1.412 | 1.00 | |
| 194_S | 198_Y | 1.407 | 0.99 | |
| 36_L | 67_L | 1.399 | 0.99 | |
| 21_V | 27_F | 1.394 | 0.99 | |
| 70_V | 73_N | 1.392 | 0.99 | |
| 180_S | 183_E | 1.381 | 0.99 | |
| 7_I | 59_M | 1.377 | 0.99 | |
| 182_D | 192_R | 1.375 | 0.99 | |
| 102_D | 116_A | 1.369 | 0.99 | |
| 199_L | 203_V | 1.366 | 0.99 | |
| 4_V | 27_F | 1.365 | 0.99 | |
| 5_L | 31_G | 1.364 | 0.99 | |
| 66_D | 69_P | 1.362 | 0.99 | |
| 41_E | 46_S | 1.349 | 0.99 | |
| 5_L | 43_I | 1.345 | 0.99 | |
| 40_K | 67_L | 1.314 | 0.99 | |
| 112_R | 115_E | 1.306 | 0.99 | |
| 24_I | 118_T | 1.304 | 0.99 | |
| 160_T | 163_T | 1.292 | 0.99 | |
| 37_E | 62_E | 1.282 | 0.99 | |
| 81_I | 102_D | 1.261 | 0.99 | |
| 2_I | 121_R | 1.256 | 0.99 | |
| 53_I | 78_S | 1.249 | 0.99 | |
| 9_D | 56_D | 1.233 | 0.98 | |
| 196_R | 199_L | 1.214 | 0.98 | |
| 43_I | 71_L | 1.211 | 0.98 | |
| 52_L | 121_R | 1.208 | 0.98 | |
| 197_K | 200_I | 1.202 | 0.98 | |
| 37_E | 41_E | 1.189 | 0.98 | |
| 170_W | 187_E | 1.185 | 0.98 | |
| 182_D | 186_N | 1.181 | 0.98 | |
| 192_R | 196_R | 1.178 | 0.98 | |
| 138_L | 172_D | 1.175 | 0.98 | |
| 39_A | 43_I | 1.172 | 0.98 | |
| 6_I | 18_R | 1.169 | 0.97 | |
| 38_K | 41_E | 1.165 | 0.97 | |
| 115_E | 119_G | 1.161 | 0.97 | |
| 193_V | 197_K | 1.159 | 0.97 | |
| 65_L | 98_Y | 1.155 | 0.97 | |
| 159_L | 162_Q | 1.155 | 0.97 | |
| 88_D | 91_T | 1.154 | 0.97 | |
| 31_G | 50_I | 1.151 | 0.97 | |
| 69_P | 94_D | 1.143 | 0.97 | |
| 30_C | 50_I | 1.138 | 0.97 | |
| 169_Q | 173_A | 1.117 | 0.96 | |
| 89_A | 93_K | 1.115 | 0.96 | |
| 5_L | 39_A | 1.111 | 0.96 | |
| 31_G | 42_I | 1.109 | 0.96 | |
| 160_T | 164_L | 1.103 | 0.96 | |
| 66_D | 70_V | 1.102 | 0.96 | |
| 193_V | 200_I | 1.098 | 0.96 | |
| 7_I | 33_A | 1.089 | 0.96 | |
| 58_Y | 85_S | 1.088 | 0.96 | |
| 68_L | 100_V | 1.085 | 0.96 | |
| 38_K | 42_I | 1.084 | 0.96 | |
| 92_I | 112_R | 1.078 | 0.95 | |
| 197_K | 201_W | 1.077 | 0.95 | |
| 33_A | 39_A | 1.064 | 0.95 | |
| 8_D | 59_M | 1.06 | 0.95 | |
| 3_N | 51_D | 1.058 | 0.95 | |
| 165_R | 169_Q | 1.057 | 0.95 | |
| 8_D | 14_A | 1.057 | 0.95 | |
| 7_I | 53_I | 1.036 | 0.94 | |
| 114_E | 118_T | 1.028 | 0.94 | |
| 94_D | 97_H | 1.015 | 0.93 | |
| 40_K | 62_E | 1.015 | 0.93 | |
| 45_N | 75_R | 1.015 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3c3wA | 2 | 0.9079 | 100 | 0.308 | Contact Map | 0.682 |
| 4gvpA | 4 | 0.841 | 100 | 0.311 | Contact Map | 0.865 |
| 4hyeA | 2 | 0.8075 | 100 | 0.326 | Contact Map | 0.862 |
| 1a04A | 2 | 0.8536 | 100 | 0.328 | Contact Map | 0.72 |
| 3kloA | 4 | 0.8787 | 100 | 0.35 | Contact Map | 0.48 |
| 4b09A | 12 | 0.9247 | 100 | 0.353 | Contact Map | 0.67 |
| 1yioA | 1 | 0.8285 | 100 | 0.355 | Contact Map | 0.684 |
| 1ys7A | 2 | 0.9079 | 100 | 0.357 | Contact Map | 0.769 |
| 3r0jA | 2 | 0.9121 | 100 | 0.36 | Contact Map | 0.688 |
| 1kgsA | 1 | 0.9079 | 100 | 0.371 | Contact Map | 0.705 |
Sequence Conservation (Image Generated using WebLogo v3)