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OPENSEQ.org

YEAL - UPF0756 membrane protein YeaL
UniProt: P0ACY6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13498
Length: 148 (147)
Sequences: 205
Seq/Len: 1.39

YEAL
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
120_T 124_V 2.194 0.99
132_V 135_L 2.024 0.98
123_G 137_A 1.766 0.94
27_S 72_P 1.67 0.92
86_L 90_A 1.535 0.86
90_A 94_I 1.524 0.86
21_N 96_S 1.524 0.86
39_L 44_P 1.489 0.84
118_V 126_L 1.472 0.83
100_G 112_L 1.467 0.83
21_N 124_V 1.451 0.82
34_V 46_I 1.427 0.80
81_L 145_V 1.405 0.79
101_R 130_V 1.401 0.79
66_I 126_L 1.397 0.78
101_R 142_S 1.393 0.78
120_T 136_I 1.385 0.78
131_P 142_S 1.361 0.76
35_R 67_A 1.328 0.73
98_L 107_G 1.324 0.73
36_V 67_A 1.321 0.73
15_L 18_I 1.318 0.72
71_L 121_V 1.315 0.72
96_S 120_T 1.291 0.70
51_L 87_V 1.283 0.70
124_V 136_I 1.275 0.69
14_A 18_I 1.273 0.69
140_L 144_I 1.23 0.65
58_L 113_V 1.217 0.64
26_V 76_L 1.216 0.63
16_G 105_L 1.214 0.63
8_I 73_P 1.212 0.63
89_I 123_G 1.212 0.63
14_A 17_F 1.21 0.63
28_I 63_M 1.201 0.62
66_I 122_L 1.179 0.60
21_N 120_T 1.177 0.60
12_L 39_L 1.176 0.60
34_V 43_F 1.174 0.59
95_V 136_I 1.162 0.58
27_S 36_V 1.148 0.57
99_G 130_V 1.147 0.57
27_S 71_L 1.146 0.57
95_V 120_T 1.145 0.57
135_L 138_A 1.137 0.56
53_I 112_L 1.13 0.55
96_S 124_V 1.127 0.55
31_L 62_V 1.115 0.54
99_G 125_A 1.112 0.53
60_I 70_T 1.109 0.53
8_I 63_M 1.101 0.52
17_F 56_I 1.099 0.52
2_F 20_H 1.097 0.52
29_L 34_V 1.096 0.52
9_L 67_A 1.087 0.51
13_A 82_N 1.077 0.50
18_I 45_W 1.068 0.49
12_L 138_A 1.063 0.48
81_L 87_V 1.061 0.48
99_G 136_I 1.057 0.48
55_I 95_V 1.056 0.48
2_F 11_G 1.056 0.48
17_F 30_V 1.046 0.47
2_F 147_K 1.046 0.47
136_I 139_G 1.041 0.46
70_T 76_L 1.04 0.46
68_S 80_F 1.036 0.46
21_N 95_V 1.033 0.45
95_V 124_V 1.032 0.45
62_V 135_L 1.028 0.45
56_I 116_L 1.028 0.45
21_N 136_I 1.024 0.44
10_L 87_V 1.023 0.44
46_I 76_L 1.022 0.44
42_F 94_I 1.021 0.44
53_I 81_L 1.021 0.44
43_F 88_A 1.02 0.44
129_G 139_G 1.009 0.43
94_I 112_L 1.008 0.43
16_G 24_V 1.008 0.43
130_V 145_V 1.008 0.43
19_S 121_V 1.007 0.43
12_L 106_M 1.004 0.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2kluA10.20956.70.953Contact Map0.17
2nq2A20.68925.20.955Contact Map0.06
2qi9A20.75684.30.957Contact Map0.141
1wu0A10.486540.958Contact Map0.023
2zy9A20.87842.80.961Contact Map0.065
2looA10.49322.70.961Contact Map0.101
4f35D40.59462.50.962Contact Map0.132
2jlnA10.87842.50.962Contact Map0.177
3orgA40.96622.30.963Contact Map0.328
3bkdA80.16222.20.963Contact Map0

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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