| UniProt: | P0ACM5 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14066 | ||
| Length: | 248 (228) | ||
| Sequences: | 3965 | ||
| Seq/Len: | 17.39 |
| YEGW
Paralog alert: 0.83 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: FRLR MNGR PHNF YEGW YIDP YIHL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 42_E | 45_N | 4.465 | 1.00 | |
| 203_F | 236_H | 3.176 | 1.00 | |
| 199_P | 215_V | 3.124 | 1.00 | |
| 35_A | 56_L | 2.986 | 1.00 | |
| 35_A | 40_V | 2.924 | 1.00 | |
| 31_T | 57_T | 2.849 | 1.00 | |
| 33_K | 74_E | 2.726 | 1.00 | |
| 80_S | 83_Y | 2.666 | 1.00 | |
| 200_D | 203_F | 2.626 | 1.00 | |
| 28_F | 59_V | 2.497 | 1.00 | |
| 115_L | 148_Y | 2.423 | 1.00 | |
| 198_M | 214_P | 2.389 | 1.00 | |
| 68_M | 77_V | 2.303 | 1.00 | |
| 128_V | 160_W | 2.23 | 1.00 | |
| 46_I | 86_Q | 2.18 | 1.00 | |
| 29_A | 70_A | 2.172 | 1.00 | |
| 77_V | 85_T | 2.136 | 1.00 | |
| 29_A | 74_E | 2.092 | 1.00 | |
| 144_K | 158_E | 2.065 | 1.00 | |
| 113_D | 148_Y | 2.05 | 1.00 | |
| 34_N | 38_S | 2.028 | 1.00 | |
| 125_P | 128_V | 1.972 | 1.00 | |
| 72_E | 77_V | 1.938 | 1.00 | |
| 142_L | 158_E | 1.938 | 1.00 | |
| 135_E | 138_S | 1.86 | 1.00 | |
| 144_K | 202_E | 1.843 | 1.00 | |
| 83_Y | 86_Q | 1.82 | 1.00 | |
| 33_K | 76_V | 1.749 | 1.00 | |
| 113_D | 151_E | 1.737 | 1.00 | |
| 193_R | 243_V | 1.723 | 1.00 | |
| 117_V | 146_I | 1.696 | 1.00 | |
| 156_I | 203_F | 1.676 | 1.00 | |
| 50_E | 61_R | 1.665 | 1.00 | |
| 138_S | 164_H | 1.664 | 1.00 | |
| 121_V | 139_D | 1.637 | 1.00 | |
| 152_E | 241_L | 1.628 | 1.00 | |
| 24_L | 27_K | 1.604 | 1.00 | |
| 195_S | 217_V | 1.591 | 1.00 | |
| 195_S | 243_V | 1.58 | 1.00 | |
| 68_M | 72_E | 1.556 | 1.00 | |
| 122_V | 142_L | 1.547 | 1.00 | |
| 118_N | 144_K | 1.542 | 1.00 | |
| 47_L | 77_V | 1.542 | 1.00 | |
| 197_R | 217_V | 1.531 | 1.00 | |
| 29_A | 33_K | 1.53 | 1.00 | |
| 110_K | 150_D | 1.527 | 1.00 | |
| 31_T | 35_A | 1.521 | 1.00 | |
| 122_V | 128_V | 1.518 | 1.00 | |
| 199_P | 212_K | 1.504 | 1.00 | |
| 121_V | 163_A | 1.494 | 1.00 | |
| 192_S | 220_Q | 1.491 | 1.00 | |
| 209_L | 215_V | 1.486 | 1.00 | |
| 114_T | 147_R | 1.475 | 1.00 | |
| 118_N | 142_L | 1.472 | 1.00 | |
| 193_R | 245_V | 1.463 | 1.00 | |
| 72_E | 79_R | 1.45 | 1.00 | |
| 78_T | 88_N | 1.441 | 1.00 | |
| 156_I | 206_H | 1.437 | 1.00 | |
| 129_A | 134_V | 1.427 | 1.00 | |
| 124_C | 140_V | 1.417 | 1.00 | |
| 196_A | 216_L | 1.403 | 0.99 | |
| 197_R | 203_F | 1.389 | 0.99 | |
| 224_D | 228_R | 1.386 | 0.99 | |
| 28_F | 64_V | 1.361 | 0.99 | |
| 185_I | 224_D | 1.36 | 0.99 | |
| 66_K | 70_A | 1.36 | 0.99 | |
| 199_P | 213_I | 1.355 | 0.99 | |
| 124_C | 129_A | 1.352 | 0.99 | |
| 120_R | 142_L | 1.346 | 0.99 | |
| 132_L | 140_V | 1.34 | 0.99 | |
| 134_V | 138_S | 1.34 | 0.99 | |
| 50_E | 65_R | 1.334 | 0.99 | |
| 66_K | 69_Q | 1.323 | 0.99 | |
| 28_F | 31_T | 1.321 | 0.99 | |
| 79_R | 85_T | 1.316 | 0.99 | |
| 35_A | 41_L | 1.305 | 0.99 | |
| 105_V | 149_V | 1.304 | 0.99 | |
| 221_V | 229_P | 1.301 | 0.99 | |
| 177_Y | 222_A | 1.297 | 0.99 | |
| 224_D | 230_I | 1.297 | 0.99 | |
| 210_D | 213_I | 1.29 | 0.99 | |
| 191_R | 245_V | 1.287 | 0.99 | |
| 178_D | 182_S | 1.272 | 0.99 | |
| 69_Q | 73_E | 1.269 | 0.99 | |
| 215_V | 236_H | 1.269 | 0.99 | |
| 217_V | 234_I | 1.262 | 0.99 | |
| 177_Y | 231_E | 1.249 | 0.99 | |
| 33_K | 37_R | 1.234 | 0.98 | |
| 28_F | 57_T | 1.222 | 0.98 | |
| 132_L | 229_P | 1.218 | 0.98 | |
| 199_P | 209_L | 1.206 | 0.98 | |
| 148_Y | 151_E | 1.187 | 0.98 | |
| 161_V | 176_L | 1.185 | 0.98 | |
| 164_H | 228_R | 1.183 | 0.98 | |
| 101_F | 105_V | 1.18 | 0.98 | |
| 25_Y | 70_A | 1.151 | 0.97 | |
| 166_I | 180_F | 1.15 | 0.97 | |
| 181_R | 186_Y | 1.136 | 0.97 | |
| 204_Q | 212_K | 1.131 | 0.97 | |
| 134_V | 140_V | 1.129 | 0.97 | |
| 124_C | 138_S | 1.127 | 0.97 | |
| 59_V | 64_V | 1.122 | 0.97 | |
| 115_L | 146_I | 1.117 | 0.96 | |
| 35_A | 57_T | 1.116 | 0.96 | |
| 36_V | 87_I | 1.111 | 0.96 | |
| 124_C | 134_V | 1.092 | 0.96 | |
| 198_M | 213_I | 1.082 | 0.96 | |
| 219_K | 234_I | 1.063 | 0.95 | |
| 186_Y | 225_Q | 1.054 | 0.95 | |
| 197_R | 215_V | 1.05 | 0.94 | |
| 26_I | 30_E | 1.043 | 0.94 | |
| 129_A | 136_A | 1.038 | 0.94 | |
| 41_L | 45_N | 1.034 | 0.94 | |
| 69_Q | 79_R | 1.031 | 0.94 | |
| 53_L | 64_V | 1.023 | 0.93 | |
| 147_R | 157_E | 1.004 | 0.93 | |
| 159_S | 231_E | 1.004 | 0.93 | |
| 201_A | 211_S | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2wv0A | 10 | 0.9476 | 100 | 0.221 | Contact Map | 0.883 |
| 3f8mA | 2 | 0.9516 | 100 | 0.237 | Contact Map | 0.756 |
| 2ra5A | 1 | 0.9637 | 100 | 0.242 | Contact Map | 0.702 |
| 3edpA | 2 | 0.9274 | 100 | 0.242 | Contact Map | 0.702 |
| 3bwgA | 3 | 0.9194 | 100 | 0.258 | Contact Map | 0.845 |
| 3eetA | 2 | 0.9879 | 100 | 0.259 | Contact Map | 0.745 |
| 3f8lA | 4 | 0.7581 | 100 | 0.455 | Contact Map | 0.778 |
| 2fa1A | 2 | 0.629 | 100 | 0.555 | Contact Map | 0.721 |
| 3hfiA | 1 | 0.6411 | 100 | 0.558 | Contact Map | 0.776 |
| 2ikkA | 2 | 0.6532 | 100 | 0.563 | Contact Map | 0.868 |
Sequence Conservation (Image Generated using WebLogo v3)