May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
SFSB - Sugar fermentation stimulation protein B
UniProt: P0ACH1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10656
Length: 92 (87)
Sequences: 173
Seq/Len: 1.99
SFSB
Paralog alert: 0.17 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
7_D 67_S 3.017 1.00
41_A 53_I 2.351 1.00
27_E 31_N 1.735 0.97
12_D 19_K 1.717 0.96
79_D 84_M 1.702 0.96
25_A 36_S 1.664 0.95
51_M 60_D 1.648 0.95
51_M 55_K 1.612 0.94
12_D 15_A 1.603 0.94
29_R 46_W 1.544 0.93
46_W 49_G 1.475 0.90
9_H 19_K 1.416 0.87
52_I 73_Q 1.415 0.87
9_H 12_D 1.385 0.86
37_T 49_G 1.359 0.84
82_Q 85_R 1.31 0.81
14_I 18_R 1.304 0.81
11_A 14_I 1.254 0.77
80_R 83_L 1.239 0.76
28_S 38_L 1.233 0.75
18_R 27_E 1.207 0.73
70_H 83_L 1.19 0.72
9_H 38_L 1.161 0.69
2_E 30_R 1.156 0.69
38_L 47_P 1.153 0.68
11_A 19_K 1.145 0.68
74_T 79_D 1.126 0.66
75_H 83_L 1.103 0.63
20_K 35_S 1.085 0.61
1_M 63_V 1.079 0.61
52_I 55_K 1.072 0.60
59_T 63_V 1.07 0.60
79_D 82_Q 1.065 0.59
37_T 48_K 1.056 0.58
4_N 43_S 1.039 0.56
51_M 81_T 1.038 0.56
20_K 31_N 1.034 0.56
17_L 22_T 1.031 0.56
58_G 87_Y 1.027 0.55
34_S 71_D 1.02 0.54
52_I 56_A 1.004 0.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1neqA10.793599.30.631Contact Map0.339
2ewtA10.717496.30.816Contact Map0.358
1y7yA20.717495.30.83Contact Map0.406
3bd1A30.815295.10.832Contact Map0.351
4f8dA20.8261950.833Contact Map0.418
3t76A10.760994.90.834Contact Map0.335
3g5gA140.826194.50.837Contact Map0.421
4i6rA20.826194.50.837Contact Map0.434
2ef8A20.815294.40.838Contact Map0.361
2b5aA40.782694.20.84Contact Map0.43
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 2.4279 seconds.