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YIBF - Uncharacterized GST-like protein YibF
UniProt: P0ACA1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11762
Length: 202 (199)
Sequences: 11376
Seq/Len: 57.17

YIBF
Paralog alert: 0.77 [within 20: 0.33] - ratio of genomes with paralogs
Cluster includes: GSTA GSTB SSPA YFCF YFCG YIBF YNCG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
2_K 29_I 3.436 1.00
68_E 91_R 3.412 1.00
183_K 187_N 3.322 1.00
21_E 191_R 3.295 1.00
72_L 87_S 2.951 1.00
2_K 27_E 2.872 1.00
20_L 196_R 2.706 1.00
19_L 26_F 2.672 1.00
41_A 47_G 2.657 1.00
20_L 26_F 2.634 1.00
138_E 180_H 2.61 1.00
5_G 12_V 2.608 1.00
58_E 85_L 2.451 1.00
135_D 178_R 2.194 1.00
142_V 180_H 2.133 1.00
83_D 86_E 2.041 1.00
53_V 59_C 1.996 1.00
120_E 124_L 1.927 1.00
173_G 176_V 1.908 1.00
5_G 28_F 1.897 1.00
2_K 53_V 1.879 1.00
182_V 186_E 1.856 1.00
43_F 51_V 1.826 1.00
72_L 91_R 1.817 1.00
4_V 53_V 1.792 1.00
40_V 51_V 1.787 1.00
32_L 35_N 1.769 1.00
17_I 194_F 1.768 1.00
21_E 193_S 1.756 1.00
146_L 158_I 1.689 1.00
180_H 183_K 1.686 1.00
53_V 57_G 1.646 1.00
89_R 92_K 1.606 1.00
43_F 53_V 1.602 1.00
131_N 177_D 1.597 1.00
18_L 67_A 1.596 1.00
4_V 31_E 1.595 1.00
22_K 71_E 1.578 1.00
186_E 190_S 1.572 1.00
81_P 90_V 1.558 1.00
151_V 156_I 1.558 1.00
93_I 140_Y 1.547 1.00
135_D 139_G 1.545 1.00
39_G 42_Q 1.537 1.00
138_E 179_P 1.521 1.00
190_S 195_A 1.509 1.00
124_L 128_E 1.463 1.00
140_Y 144_G 1.455 1.00
24_I 74_N 1.451 1.00
60_W 88_L 1.385 0.99
147_K 152_N 1.357 0.99
18_L 22_K 1.338 0.99
40_V 43_F 1.326 0.99
145_T 188_L 1.309 0.99
1_M 52_L 1.3 0.99
159_A 188_L 1.3 0.99
151_V 191_R 1.294 0.99
18_L 79_M 1.292 0.99
127_R 131_N 1.286 0.99
15_L 67_A 1.285 0.99
68_E 95_A 1.274 0.99
61_F 92_K 1.245 0.98
79_M 156_I 1.244 0.98
176_V 182_V 1.244 0.98
3_L 19_L 1.243 0.98
21_E 151_V 1.219 0.98
97_A 158_I 1.218 0.98
48_K 62_D 1.209 0.98
86_E 150_T 1.208 0.98
80_L 90_V 1.203 0.98
192_E 196_R 1.193 0.98
67_A 153_L 1.183 0.98
129_K 132_R 1.179 0.98
21_E 156_I 1.177 0.98
84_P 88_L 1.173 0.98
115_A 118_Q 1.172 0.98
135_D 177_D 1.169 0.97
95_A 98_D 1.165 0.97
138_E 142_V 1.154 0.97
73_M 84_P 1.147 0.97
85_L 89_R 1.117 0.96
55_E 69_Y 1.107 0.96
14_K 63_S 1.106 0.96
90_V 152_N 1.084 0.96
9_S 12_V 1.057 0.95
186_E 189_F 1.054 0.95
14_K 157_A 1.053 0.95
125_R 129_K 1.045 0.94
15_L 66_I 1.041 0.94
185_V 189_F 1.034 0.94
140_Y 143_D 1.034 0.94
80_L 91_R 1.031 0.94
16_S 20_L 1.028 0.94
151_V 188_L 1.02 0.93
145_T 187_N 1.017 0.93
70_I 74_N 1.012 0.93
89_R 144_G 1.008 0.93
119_S 122_E 1.006 0.93
139_G 142_V 1.006 0.93
187_N 190_S 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4jedA111000.103Contact Map0.645
4mk3A111000.11Contact Map0.692
3touA211000.117Contact Map0.749
3r2qA10.9951000.123Contact Map0.751
4gltA411000.132Contact Map0.774
3m0fA20.9951000.132Contact Map0.73
4n0vA20.99011000.142Contact Map0.755
4hojA10.96041000.144Contact Map0.737
4id0A20.99011000.146Contact Map0.693
3lypA20.96041000.148Contact Map0.76

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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