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OPENSEQ.org
NIRC - Probable nitrite transporter
UniProt: P0AC26 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10654
Length: 268 (252)
Sequences: 1043
Seq/Len: 4.14
NIRC
Paralog alert: 0.56 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: FOCA FOCB NIRC YFDC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
154_F 235_L 6.715 1.00
154_F 231_L 4.693 1.00
231_L 235_L 3.708 1.00
31_S 111_G 3.119 1.00
153_L 229_V 3.081 1.00
91_V 98_H 3.059 1.00
32_A 118_F 2.745 1.00
177_A 181_I 2.494 1.00
109_W 230_T 2.388 1.00
13_A 90_G 2.255 1.00
39_G 119_V 2.215 1.00
80_F 84_T 2.19 1.00
150_A 228_W 2.151 1.00
66_G 184_W 2.119 1.00
44_L 189_A 2.034 1.00
70_T 180_F 1.962 1.00
105_L 234_T 1.951 1.00
25_L 111_G 1.949 1.00
162_W 240_F 1.847 1.00
45_I 61_M 1.679 0.99
71_L 166_L 1.612 0.99
40_L 162_W 1.592 0.99
174_T 178_A 1.581 0.99
109_W 198_S 1.572 0.98
75_A 169_W 1.557 0.98
106_P 110_L 1.537 0.98
44_L 188_L 1.523 0.98
148_A 156_K 1.519 0.98
110_L 114_V 1.512 0.98
113_L 202_M 1.507 0.98
83_H 104_I 1.5 0.98
80_F 234_T 1.48 0.97
140_S 143_L 1.472 0.97
32_A 114_V 1.469 0.97
68_A 191_I 1.46 0.97
109_W 226_L 1.434 0.97
36_A 39_G 1.421 0.97
170_M 182_A 1.421 0.97
17_A 96_I 1.416 0.96
56_V 60_V 1.41 0.96
40_L 119_V 1.404 0.96
198_S 230_T 1.399 0.96
158_A 235_L 1.377 0.96
205_F 222_I 1.352 0.95
223_G 227_L 1.351 0.95
160_C 199_I 1.33 0.94
91_V 96_I 1.328 0.94
149_P 152_V 1.322 0.94
114_V 117_V 1.321 0.94
122_L 159_L 1.317 0.94
63_A 184_W 1.312 0.94
14_A 95_S 1.296 0.93
24_P 107_Q 1.288 0.93
150_A 153_L 1.283 0.93
148_A 153_L 1.243 0.91
48_L 60_V 1.236 0.91
63_A 188_L 1.221 0.90
201_N 225_N 1.217 0.90
11_A 95_S 1.215 0.90
33_M 37_Y 1.212 0.90
150_A 154_F 1.21 0.90
216_A 219_L 1.209 0.90
218_T 221_G 1.202 0.90
102_W 106_P 1.198 0.89
142_A 145_K 1.186 0.89
101_M 105_L 1.179 0.88
85_M 241_M 1.174 0.88
161_N 190_F 1.172 0.88
239_V 244_G 1.168 0.88
121_M 125_W 1.168 0.88
36_A 162_W 1.161 0.87
215_E 218_T 1.158 0.87
42_I 204_L 1.157 0.87
198_S 226_L 1.154 0.87
113_L 117_V 1.15 0.87
199_I 244_G 1.148 0.86
158_A 239_V 1.146 0.86
230_T 234_T 1.145 0.86
138_V 207_L 1.142 0.86
73_I 168_I 1.14 0.86
120_A 207_L 1.139 0.86
78_E 83_H 1.138 0.86
77_S 245_Y 1.135 0.86
91_V 94_G 1.129 0.85
209_W 222_I 1.12 0.85
183_I 187_L 1.12 0.85
106_P 157_G 1.119 0.85
121_M 210_F 1.119 0.85
73_I 183_I 1.111 0.84
91_V 101_M 1.108 0.84
99_G 103_A 1.103 0.83
190_F 201_N 1.094 0.83
37_Y 77_S 1.09 0.82
157_G 230_T 1.084 0.82
20_S 103_A 1.083 0.82
165_C 202_M 1.069 0.81
94_G 98_H 1.065 0.80
198_S 229_V 1.065 0.80
122_L 155_F 1.056 0.79
37_Y 71_L 1.043 0.78
30_S 169_W 1.043 0.78
241_M 245_Y 1.042 0.78
43_I 129_S 1.039 0.78
80_F 230_T 1.037 0.78
237_G 242_G 1.027 0.77
75_A 245_Y 1.021 0.76
34_A 80_F 1.017 0.76
16_I 145_K 1.014 0.76
33_M 244_G 1.012 0.75
25_L 107_Q 1.009 0.75
119_V 162_W 1.002 0.74
191_I 200_A 1.001 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tdsE50.97391000.094Contact Map0.762
4fc4A100.97391000.117Contact Map0.733
3kcuA50.94031000.118Contact Map0.745
3klyA50.92541000.125Contact Map0.72
3d9sA40.865767.50.948Contact Map0.508
3zojA10.9104670.948Contact Map0.433
3iyzA10.921663.40.949Contact Map0.033
1ldfA10.888157.40.951Contact Map0.4
2zz9A10.876954.80.952Contact Map0.356
3c02A10.876951.50.953Contact Map0.4
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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