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OPENSEQ.org
SURA - Chaperone SurA
UniProt: P0ABZ6 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10985
Length: 428 (410)
Sequences: 1345
Seq/Len: 3.28
SURA
Paralog alert: 0.74 [within 20: 0.02] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
311_A 315_K 3.866 1.00
33_N 82_Q 3.379 1.00
313_D 318_K 2.908 1.00
347_D 354_R 2.904 1.00
30_A 71_M 2.895 1.00
344_A 349_F 2.845 1.00
362_K 382_D 2.759 1.00
205_Q 210_A 2.697 1.00
320_T 323_A 2.548 1.00
361_N 364_Q 2.492 1.00
286_H 340_D 2.415 1.00
196_E 200_R 2.324 1.00
371_S 374_G 2.277 1.00
93_D 133_R 2.217 1.00
304_R 308_E 2.202 1.00
288_R 379_E 2.181 1.00
110_T 113_Q 2.141 1.00
286_H 381_L 2.123 1.00
353_F 376_H 2.083 1.00
288_R 381_L 2.046 1.00
311_A 377_L 2.015 1.00
292_L 303_A 1.989 1.00
97_D 129_R 1.985 1.00
310_I 328_F 1.968 1.00
83_M 86_K 1.966 1.00
311_A 368_P 1.957 1.00
45_L 77_D 1.956 1.00
284_E 384_R 1.944 1.00
95_Q 140_E 1.939 1.00
92_S 95_Q 1.914 1.00
311_A 367_A 1.907 1.00
206_A 215_L 1.874 0.99
369_V 378_I 1.856 0.99
188_T 191_Q 1.853 0.99
360_L 366_S 1.847 0.99
307_L 377_L 1.847 0.99
233_W 272_D 1.84 0.99
329_S 339_G 1.825 0.99
368_P 375_W 1.814 0.99
71_M 75_I 1.813 0.99
173_E 274_R 1.812 0.99
286_H 382_D 1.808 0.99
289_H 376_H 1.804 0.99
192_V 260_R 1.778 0.99
175_N 230_Q 1.775 0.99
331_D 339_G 1.763 0.99
41_D 78_Q 1.756 0.99
314_I 324_A 1.756 0.99
307_L 311_A 1.749 0.99
193_N 197_S 1.733 0.99
158_E 162_Q 1.721 0.99
309_Q 313_D 1.718 0.99
321_F 339_G 1.715 0.99
310_I 324_A 1.701 0.99
353_F 378_I 1.688 0.99
351_P 355_D 1.688 0.99
252_K 272_D 1.664 0.98
203_V 207_R 1.641 0.98
409_E 412_S 1.638 0.98
181_I 195_A 1.625 0.98
39_E 43_D 1.623 0.98
357_L 380_L 1.62 0.98
356_A 369_V 1.614 0.98
360_L 380_L 1.581 0.98
341_L 376_H 1.561 0.97
261_S 266_H 1.541 0.97
340_D 381_L 1.535 0.97
344_A 357_L 1.523 0.97
398_Y 402_M 1.522 0.97
325_A 338_G 1.521 0.97
312_A 316_S 1.487 0.96
285_V 383_T 1.485 0.96
42_V 71_M 1.478 0.96
373_F 376_H 1.472 0.96
361_N 380_L 1.472 0.96
220_S 229_G 1.453 0.95
158_E 394_K 1.443 0.95
201_A 205_Q 1.442 0.95
323_A 327_E 1.436 0.95
300_D 370_H 1.427 0.95
191_Q 194_E 1.424 0.95
331_D 334_S 1.421 0.95
203_V 267_I 1.42 0.95
321_F 325_A 1.416 0.95
197_S 201_A 1.398 0.94
291_L 376_H 1.394 0.94
50_K 63_D 1.391 0.94
45_L 74_L 1.388 0.94
31_V 36_V 1.364 0.93
397_A 401_L 1.36 0.93
216_A 220_S 1.36 0.93
287_A 344_A 1.359 0.93
35_G 85_Q 1.34 0.92
203_V 258_P 1.337 0.92
270_V 397_A 1.335 0.92
250_A 254_D 1.33 0.92
201_A 204_D 1.33 0.92
308_E 312_A 1.329 0.92
49_V 52_N 1.324 0.91
112_D 116_S 1.32 0.91
154_P 158_E 1.315 0.91
72_E 76_M 1.309 0.91
370_H 375_W 1.305 0.91
35_G 78_Q 1.304 0.91
260_R 265_F 1.302 0.91
204_D 208_N 1.295 0.90
212_F 229_G 1.289 0.90
360_L 364_Q 1.28 0.90
77_D 134_K 1.277 0.89
43_D 47_Q 1.275 0.89
190_D 194_E 1.275 0.89
250_A 256_V 1.26 0.89
416_E 420_S 1.256 0.88
51_L 54_A 1.256 0.88
291_L 373_F 1.246 0.88
395_D 398_Y 1.242 0.88
288_R 340_D 1.241 0.88
408_E 412_S 1.239 0.87
112_D 115_R 1.239 0.87
350_D 373_F 1.238 0.87
324_A 328_F 1.233 0.87
329_S 334_S 1.227 0.87
49_V 70_I 1.222 0.86
371_S 376_H 1.221 0.86
130_N 133_R 1.215 0.86
289_H 339_G 1.214 0.86
73_R 77_D 1.214 0.86
204_D 207_R 1.214 0.86
33_N 79_I 1.212 0.86
200_R 204_D 1.21 0.86
369_V 377_L 1.207 0.86
212_F 220_S 1.206 0.85
304_R 370_H 1.204 0.85
325_A 339_G 1.199 0.85
312_A 315_K 1.194 0.85
140_E 143_N 1.186 0.84
84_G 137_I 1.185 0.84
197_S 200_R 1.181 0.84
352_A 355_D 1.177 0.84
114_M 125_Y 1.176 0.83
322_A 338_G 1.175 0.83
292_L 310_I 1.172 0.83
319_T 324_A 1.17 0.83
314_I 365_M 1.165 0.83
290_I 321_F 1.164 0.83
153_L 156_E 1.163 0.83
304_R 375_W 1.161 0.82
289_H 353_F 1.159 0.82
190_D 193_N 1.158 0.82
299_T 302_Q 1.148 0.81
321_F 329_S 1.147 0.81
317_G 320_T 1.143 0.81
396_R 399_R 1.143 0.81
343_W 382_D 1.141 0.81
42_V 70_I 1.132 0.80
81_L 138_I 1.131 0.80
289_H 373_F 1.129 0.80
29_A 79_I 1.127 0.80
394_K 398_Y 1.123 0.79
216_A 229_G 1.112 0.78
225_A 229_G 1.111 0.78
353_F 373_F 1.109 0.78
114_M 129_R 1.108 0.78
343_W 384_R 1.104 0.78
285_V 357_L 1.1 0.77
202_I 219_H 1.092 0.77
38_L 41_D 1.091 0.77
233_W 274_R 1.086 0.76
33_N 421_A 1.085 0.76
29_A 70_I 1.084 0.76
242_I 263_V 1.077 0.75
325_A 335_A 1.075 0.75
289_H 329_S 1.07 0.75
309_Q 312_A 1.069 0.75
287_A 349_F 1.068 0.74
202_I 215_L 1.068 0.74
89_V 141_V 1.061 0.74
251_K 254_D 1.057 0.73
286_H 343_W 1.057 0.73
389_T 393_Q 1.048 0.72
113_Q 116_S 1.047 0.72
42_V 46_M 1.046 0.72
289_H 331_D 1.045 0.72
241_G 245_Q 1.045 0.72
45_L 48_S 1.041 0.72
158_E 161_A 1.035 0.71
346_P 354_R 1.032 0.71
306_K 328_F 1.032 0.71
196_E 265_F 1.027 0.70
68_H 72_E 1.027 0.70
405_K 408_E 1.023 0.70
242_I 261_S 1.021 0.70
43_D 67_R 1.019 0.69
255_I 267_I 1.017 0.69
28_V 31_V 1.015 0.69
363_G 381_L 1.01 0.68
349_F 373_F 1.01 0.68
315_K 365_M 1.009 0.68
177_S 271_N 1.008 0.68
338_G 376_H 1.008 0.68
362_K 383_T 1.006 0.68
35_G 82_Q 1.002 0.68
46_M 70_I 1.001 0.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1m5yA40.95331000.189Contact Map0.734
3nrkA10.68691000.495Contact Map0.582
3rgcA20.58411000.573Contact Map0.643
3rfwA10.57241000.587Contact Map0.602
4g2pA20.25799.90.741Contact Map0.702
1yw5A10.364599.90.743Contact Map0.722
2jzvA10.245399.90.752Contact Map0.686
2pv1A10.233699.90.752Contact Map0.686
2lj4A10.23699.90.752Contact Map0.736
3gpkA20.259399.90.757Contact Map0.733
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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