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FLIG - Flagellar motor switch protein FliG
UniProt: P0ABZ1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11654
Length: 331 (329)
Sequences: 730
Seq/Len: 2.22
FLIG
Paralog alert: 0.15 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
9_K 58_E 2.78 1.00
298_L 331_V 2.539 1.00
239_L 312_V 2.502 1.00
275_L 287_R 2.488 1.00
249_R 320_E 2.458 1.00
244_D 273_K 2.454 1.00
242_V 246_S 2.43 1.00
8_D 40_A 2.248 1.00
314_R 318_T 2.246 1.00
243_D 246_S 2.209 1.00
268_Q 272_E 2.16 1.00
258_S 307_A 2.055 0.99
30_S 33_E 2.002 0.99
122_I 130_I 1.992 0.99
261_I 296_V 1.953 0.99
244_D 276_R 1.812 0.98
199_A 229_I 1.764 0.98
48_S 51_Q 1.739 0.97
244_D 286_L 1.738 0.97
197_R 232_E 1.717 0.97
238_N 241_D 1.706 0.97
207_K 210_Q 1.691 0.97
24_E 27_K 1.672 0.96
283_A 287_R 1.667 0.96
328_D 331_V 1.642 0.96
115_P 146_L 1.625 0.96
272_E 287_R 1.6 0.95
18_G 76_Y 1.591 0.95
20_D 83_K 1.582 0.95
126_H 160_R 1.581 0.95
57_A 61_Q 1.579 0.95
113_M 118_A 1.556 0.94
13_L 17_I 1.545 0.94
260_L 286_L 1.513 0.93
247_I 277_N 1.499 0.92
122_I 180_N 1.493 0.92
23_A 215_I 1.485 0.92
118_A 145_I 1.452 0.91
14_L 215_I 1.451 0.91
26_F 80_V 1.44 0.90
204_N 236_F 1.44 0.90
244_D 277_N 1.424 0.90
251_L 282_A 1.41 0.89
229_I 233_M 1.401 0.89
128_Q 160_R 1.398 0.89
254_V 308_I 1.394 0.88
247_I 289_D 1.375 0.87
72_N 77_L 1.358 0.87
260_L 293_R 1.358 0.87
219_R 230_I 1.352 0.86
250_L 312_V 1.331 0.85
23_A 84_A 1.313 0.84
268_Q 271_R 1.308 0.84
246_S 322_V 1.297 0.83
22_A 34_V 1.295 0.83
14_L 37_L 1.283 0.82
6_G 14_L 1.277 0.82
153_L 157_V 1.272 0.81
62_E 261_I 1.268 0.81
242_V 250_L 1.268 0.81
240_V 270_L 1.261 0.80
130_I 153_L 1.256 0.80
249_R 253_E 1.251 0.80
250_L 321_M 1.243 0.79
73_A 77_L 1.236 0.79
228_K 231_D 1.235 0.79
58_E 62_E 1.233 0.78
158_M 203_I 1.229 0.78
161_I 202_I 1.226 0.78
156_D 161_I 1.224 0.78
282_A 286_L 1.222 0.78
273_K 282_A 1.206 0.76
129_I 238_N 1.205 0.76
236_F 262_A 1.196 0.75
9_K 55_V 1.19 0.75
259_L 286_L 1.18 0.74
132_T 238_N 1.17 0.73
262_A 308_I 1.17 0.73
249_R 315_L 1.17 0.73
167_V 173_A 1.166 0.73
5_T 8_D 1.162 0.72
100_T 103_T 1.154 0.72
312_V 323_I 1.149 0.71
247_I 252_Q 1.145 0.71
276_R 321_M 1.143 0.71
203_I 214_V 1.143 0.71
285_I 289_D 1.141 0.70
251_L 311_I 1.141 0.70
248_Q 277_N 1.136 0.70
158_M 229_I 1.136 0.70
50_K 54_D 1.135 0.70
203_I 206_M 1.127 0.69
8_D 51_Q 1.123 0.69
216_T 220_E 1.12 0.68
115_P 144_D 1.118 0.68
256_S 286_L 1.117 0.68
93_L 289_D 1.113 0.68
156_D 160_R 1.109 0.67
253_E 314_R 1.109 0.67
93_L 177_E 1.1 0.66
231_D 306_K 1.1 0.66
227_Q 231_D 1.1 0.66
61_Q 254_V 1.096 0.66
15_M 44_V 1.094 0.66
290_L 293_R 1.092 0.65
195_G 225_L 1.091 0.65
260_L 290_L 1.091 0.65
289_D 306_K 1.09 0.65
5_T 156_D 1.084 0.65
115_P 158_M 1.084 0.65
263_L 290_L 1.083 0.65
21_R 317_E 1.083 0.65
22_A 84_A 1.081 0.64
197_R 201_E 1.079 0.64
264_K 294_G 1.075 0.64
271_R 287_R 1.074 0.64
156_D 174_E 1.07 0.63
281_R 315_L 1.069 0.63
169_P 194_G 1.064 0.63
286_L 327_E 1.06 0.62
239_L 309_L 1.06 0.62
251_L 254_V 1.059 0.62
158_M 199_A 1.048 0.61
168_Q 212_E 1.048 0.61
22_A 26_F 1.047 0.61
204_N 233_M 1.044 0.60
154_R 214_V 1.044 0.60
321_M 331_V 1.043 0.60
204_N 262_A 1.043 0.60
143_A 183_L 1.041 0.60
143_A 322_V 1.04 0.60
133_I 183_L 1.036 0.59
277_N 302_E 1.033 0.59
228_K 320_E 1.032 0.59
18_G 33_E 1.03 0.59
130_I 157_V 1.029 0.59
112_F 175_L 1.024 0.58
14_L 114_E 1.021 0.58
259_L 301_V 1.02 0.58
10_S 39_A 1.019 0.58
256_S 260_L 1.019 0.58
231_D 265_G 1.019 0.58
206_M 211_E 1.018 0.57
54_D 61_Q 1.018 0.57
84_A 195_G 1.016 0.57
257_E 271_R 1.014 0.57
34_V 85_L 1.013 0.57
233_M 278_M 1.012 0.57
73_A 316_A 1.01 0.57
37_L 40_A 1.01 0.57
28_H 108_E 1.007 0.56
289_D 292_N 1.003 0.56
26_F 229_I 1.001 0.56
86_G 90_A 1 0.55
66_F 75_D 1 0.55
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3hjlA10.97581000.016Contact Map0.496
3pkrA10.83991000.256Contact Map0.556
4fhrB10.64951000.303Contact Map0.577
2ouxA20.664795.10.934Contact Map0.355
2zy9A20.595294.50.937Contact Map0.333
2yvyA10.534788.40.947Contact Map0.229
3b34A10.516672.30.955Contact Map0.142
3ebhA10.510671.10.955Contact Map0.223
2gtqA10.5136670.957Contact Map0.083
3kxrA10.268944.20.962Contact Map0.337
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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