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OPENSEQ.org
ELBB - Enhancing lycopene biosynthesis protein 2
UniProt: P0ABU5 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11383
Length: 217 (216)
Sequences: 286
Seq/Len: 1.32
ELBB
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
42_D 77_P 3.032 1.00
163_L 168_A 2.745 1.00
103_N 107_L 2.691 1.00
195_A 201_A 2.303 0.99
29_I 36_A 2.272 0.99
7_I 91_V 2.2 0.99
5_G 86_L 2.159 0.99
82_D 85_E 2.102 0.98
81_A 120_L 2.092 0.98
90_I 209_V 2.047 0.98
151_L 163_L 2.037 0.98
50_N 53_T 1.994 0.97
46_V 106_S 1.944 0.97
119_A 123_A 1.923 0.96
30_S 199_A 1.868 0.96
5_G 37_V 1.866 0.96
34_A 213_L 1.851 0.95
81_A 124_M 1.725 0.93
187_V 212_V 1.704 0.92
43_K 63_V 1.654 0.90
132_G 208_L 1.651 0.90
43_K 114_D 1.648 0.90
121_A 145_F 1.637 0.90
103_N 112_T 1.614 0.89
149_L 186_I 1.613 0.89
95_F 98_A 1.603 0.88
26_L 38_C 1.584 0.88
142_P 168_A 1.57 0.87
209_V 212_V 1.548 0.86
150_R 169_E 1.541 0.86
196_Q 200_E 1.531 0.85
121_A 131_L 1.528 0.85
90_I 212_V 1.506 0.84
48_V 59_E 1.493 0.83
131_L 145_F 1.486 0.83
28_A 206_D 1.421 0.79
25_T 90_I 1.412 0.78
125_H 145_F 1.406 0.78
132_G 212_V 1.349 0.73
211_R 214_V 1.34 0.73
20_H 70_I 1.336 0.72
189_T 204_G 1.334 0.72
44_Q 60_T 1.333 0.72
111_C 143_K 1.328 0.72
102_S 215_L 1.314 0.71
141_L 188_T 1.303 0.70
153_I 159_T 1.295 0.69
37_V 86_L 1.284 0.68
39_F 86_L 1.26 0.66
159_T 170_H 1.26 0.66
9_S 17_S 1.26 0.66
111_C 166_M 1.259 0.66
3_K 35_Q 1.245 0.65
5_G 124_M 1.237 0.64
39_F 81_A 1.236 0.64
133_F 141_L 1.221 0.62
17_S 118_K 1.22 0.62
116_E 119_A 1.217 0.62
5_G 120_L 1.21 0.61
160_A 170_H 1.208 0.61
40_A 63_V 1.205 0.61
118_K 122_Q 1.197 0.60
125_H 184_N 1.197 0.60
178_I 207_K 1.191 0.60
91_V 121_A 1.188 0.59
185_K 215_L 1.182 0.59
49_I 110_E 1.181 0.59
86_L 124_M 1.179 0.58
122_Q 140_M 1.161 0.57
47_D 54_G 1.159 0.56
6_V 26_L 1.155 0.56
180_V 187_V 1.145 0.55
13_V 20_H 1.139 0.54
8_L 17_S 1.136 0.54
150_R 179_V 1.13 0.54
76_R 80_Q 1.13 0.54
7_I 121_A 1.117 0.52
29_I 168_A 1.109 0.51
27_L 31_R 1.108 0.51
50_N 55_E 1.105 0.51
175_V 191_A 1.097 0.50
99_K 105_A 1.079 0.48
36_A 86_L 1.078 0.48
30_S 67_A 1.067 0.47
132_G 209_V 1.066 0.47
5_G 81_A 1.057 0.46
11_C 19_I 1.048 0.45
4_I 213_L 1.045 0.45
24_L 27_L 1.045 0.45
12_G 16_G 1.044 0.45
18_E 136_I 1.043 0.45
175_V 205_I 1.041 0.45
208_L 212_V 1.038 0.44
191_A 205_I 1.029 0.43
37_V 171_V 1.028 0.43
42_D 78_L 1.023 0.43
29_I 34_A 1.023 0.43
15_D 21_E 1.016 0.42
168_A 190_P 1.013 0.42
6_V 38_C 1.013 0.42
17_S 200_E 1.003 0.41
189_T 205_I 1.002 0.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3l3bA20.99081000.633Contact Map0.659
1vhqA211000.643Contact Map0.755
1n57A10.912499.80.794Contact Map0.448
4i2nA60.907899.80.799Contact Map0.611
1rw7A10.903299.80.803Contact Map0.632
3kklA20.903299.80.808Contact Map0.664
3n7tA10.889499.80.808Contact Map0.543
2iufA20.672899.70.814Contact Map0.516
4lruA10.875699.70.814Contact Map0.625
1u9cA10.866499.70.816Contact Map0.537
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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