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OPENSEQ.org

EUTM - Ethanolamine utilization protein EutM
UniProt: P0ABF4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14187
Length: 97 (90)
Sequences: 787
Seq/Len: 8.74

EUTM
Paralog alert: 0.96 [within 20: 0.77] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
22_M 45_V 3.675 1.00
15_L 43_A 2.393 1.00
56_T 72_V 2.347 1.00
56_T 74_V 2.234 1.00
60_A 72_V 2.194 1.00
49_V 76_P 1.976 1.00
46_R 83_E 1.949 1.00
53_K 57_D 1.789 1.00
35_Q 38_G 1.713 1.00
3_A 76_P 1.627 1.00
12_L 16_I 1.605 1.00
33_V 38_G 1.588 1.00
57_D 61_A 1.558 1.00
14_A 66_I 1.447 0.99
45_V 56_T 1.441 0.99
4_L 44_M 1.401 0.99
21_A 59_G 1.398 0.99
48_D 51_A 1.364 0.99
28_V 45_V 1.331 0.99
27_R 50_A 1.327 0.99
22_M 59_G 1.326 0.99
80_G 84_E 1.313 0.99
60_A 69_L 1.312 0.99
10_R 68_E 1.292 0.98
19_S 43_A 1.285 0.98
19_S 30_L 1.283 0.98
81_D 84_E 1.227 0.98
61_A 64_Q 1.221 0.98
37_G 41_C 1.202 0.97
43_A 50_A 1.197 0.97
21_A 25_A 1.191 0.97
61_A 65_R 1.106 0.95
15_L 33_V 1.105 0.95
37_G 77_R 1.095 0.95
56_T 60_A 1.078 0.94
6_M 44_M 1.065 0.94
22_M 37_G 1.065 0.94
9_T 18_A 1.063 0.94
5_G 56_T 1.055 0.93
51_A 54_A 1.049 0.93
21_A 66_I 1.043 0.93
23_V 27_R 1.033 0.92
49_V 74_V 1.029 0.92
50_A 54_A 1.024 0.92
10_R 70_V 1.016 0.91
49_V 52_C 1.007 0.91
63_A 69_L 1.002 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3mpyA111000.097Contact Map0.627
2a1bA12199.90.133Contact Map0.692
3bn4A6199.90.136Contact Map0.733
3ssrB2199.90.137Contact Map0.71
2a10A6199.90.138Contact Map0.683
3ssqA6199.90.141Contact Map0.741
3ngkA10.948599.90.145Contact Map0.699
3gv2A6199.90.148Contact Map
4axjA3199.90.164Contact Map0.682
3cimA30.989799.90.199Contact Map0.723

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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