May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
ATPB - ATP synthase subunit beta
UniProt: P0ABB4 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10101
Length: 460 (458)
Sequences: 3686
Seq/Len: 8.05
ATPB
Paralog alert: 0.63 [within 20: 0.35] - ratio of genomes with paralogs
Cluster includes: ATPA ATPB FLII
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
90_N 94_E 7.88 1.00
28_D 71_D 3.945 1.00
323_S 336_D 3.802 1.00
83_A 105_E 3.436 1.00
352_Q 356_D 3.407 1.00
178_A 224_G 3.377 1.00
142_K 237_D 3.342 1.00
420_S 423_D 3.044 1.00
99_K 195_T 2.894 1.00
447_V 456_K 2.841 1.00
353_E 429_K 2.759 1.00
430_G 436_Y 2.737 1.00
430_G 435_E 2.721 1.00
192_H 196_D 2.645 1.00
108_W 112_R 2.618 1.00
329_L 398_Q 2.599 1.00
74_H 77_E 2.537 1.00
192_H 195_T 2.532 1.00
228_A 291_I 2.451 1.00
455_E 458_K 2.392 1.00
133_V 335_V 2.383 1.00
409_E 415_P 2.366 1.00
89_M 227_M 2.362 1.00
447_V 453_A 2.338 1.00
125_E 142_K 2.298 1.00
246_Y 250_L 2.269 1.00
30_L 69_V 2.268 1.00
77_E 107_R 2.268 1.00
361_V 397_I 2.255 1.00
176_V 228_A 2.25 1.00
417_K 452_E 2.245 1.00
357_T 429_K 2.215 1.00
174_Y 236_R 2.199 1.00
439_L 454_V 2.188 1.00
127_L 173_G 2.188 1.00
304_L 321_V 2.167 1.00
360_G 363_S 2.152 1.00
195_T 200_I 2.12 1.00
87_R 97_D 2.093 1.00
82_K 236_R 2.088 1.00
174_Y 204_S 2.064 1.00
204_S 227_M 2.054 1.00
359_R 362_Q 2.011 1.00
331_I 398_Q 2.009 1.00
392_A 395_R 2.003 1.00
191_Y 205_L 1.999 1.00
439_L 453_A 1.997 1.00
158_V 405_F 1.994 1.00
225_L 291_I 1.985 1.00
140_F 320_V 1.936 1.00
82_K 234_E 1.923 1.00
206_V 227_M 1.907 1.00
78_V 227_M 1.874 1.00
121_S 124_Q 1.85 1.00
83_A 103_G 1.832 1.00
436_Y 454_V 1.733 1.00
443_A 457_A 1.72 1.00
452_E 455_E 1.718 1.00
198_N 201_D 1.717 1.00
360_G 432_M 1.711 1.00
16_V 69_V 1.691 1.00
449_S 453_A 1.685 1.00
426_R 430_G 1.681 1.00
225_L 295_Q 1.662 1.00
369_Q 372_K 1.649 1.00
82_K 230_K 1.647 1.00
89_M 102_I 1.647 1.00
137_M 361_V 1.642 1.00
297_V 312_T 1.637 1.00
140_F 294_V 1.634 1.00
429_K 433_E 1.622 1.00
165_R 169_I 1.6 1.00
364_I 432_M 1.587 1.00
32_V 41_L 1.575 1.00
16_V 54_T 1.574 1.00
31_E 70_K 1.573 1.00
176_V 227_M 1.573 1.00
455_E 459_K 1.567 1.00
434_G 437_D 1.561 1.00
165_R 170_E 1.554 1.00
6_I 67_L 1.544 1.00
304_L 339_D 1.544 1.00
235_G 288_T 1.543 1.00
83_A 104_E 1.536 1.00
426_R 451_E 1.535 1.00
440_P 443_A 1.519 1.00
106_E 230_K 1.5 1.00
41_L 54_T 1.495 1.00
325_Q 328_S 1.49 0.99
89_M 206_V 1.486 0.99
184_T 209_Q 1.479 0.99
238_V 291_I 1.468 0.99
136_L 424_T 1.459 0.99
350_V 355_Y 1.457 0.99
357_T 425_I 1.45 0.99
108_W 230_K 1.442 0.99
76_I 110_I 1.436 0.99
96_V 207_Y 1.435 0.99
33_Q 68_D 1.416 0.99
131_I 134_I 1.411 0.99
5_K 68_D 1.41 0.99
131_I 159_N 1.404 0.99
138_C 335_V 1.389 0.99
91_V 96_V 1.384 0.99
8_Q 15_D 1.382 0.99
84_T 227_M 1.37 0.99
33_Q 70_K 1.368 0.99
116_S 120_L 1.365 0.99
165_R 406_F 1.349 0.99
225_L 283_I 1.337 0.99
148_L 160_M 1.335 0.99
31_E 38_R 1.335 0.99
78_V 223_T 1.329 0.99
272_L 275_E 1.321 0.99
360_G 433_E 1.318 0.98
188_N 192_H 1.31 0.98
108_W 226_T 1.299 0.98
172_S 236_R 1.299 0.98
326_I 331_I 1.295 0.98
95_P 100_G 1.282 0.98
139_P 345_L 1.281 0.98
31_E 40_V 1.28 0.98
91_V 223_T 1.269 0.98
367_R 370_E 1.269 0.98
439_L 443_A 1.26 0.98
447_V 452_E 1.259 0.98
125_E 237_D 1.258 0.98
453_A 456_K 1.253 0.98
104_E 107_R 1.252 0.98
410_V 414_S 1.25 0.98
331_I 402_S 1.249 0.98
90_N 212_E 1.249 0.98
414_S 446_M 1.249 0.98
85_L 174_Y 1.247 0.98
273_A 280_Q 1.247 0.98
442_Q 460_L 1.243 0.98
350_V 354_H 1.238 0.97
161_M 207_Y 1.236 0.97
112_R 233_D 1.233 0.97
321_V 324_R 1.224 0.97
3_T 68_D 1.214 0.97
430_G 454_V 1.214 0.97
439_L 447_V 1.213 0.97
174_Y 231_F 1.213 0.97
16_V 19_P 1.209 0.97
385_E 389_L 1.2 0.97
124_Q 288_T 1.199 0.97
232_R 286_T 1.199 0.97
128_E 135_D 1.198 0.97
178_A 242_V 1.196 0.97
195_T 201_D 1.185 0.96
372_K 376_A 1.168 0.96
439_L 457_A 1.161 0.96
230_K 234_E 1.159 0.96
204_S 231_F 1.158 0.96
375_I 391_V 1.155 0.96
421_L 425_I 1.154 0.96
396_K 399_R 1.148 0.96
119_E 287_K 1.142 0.95
360_G 364_I 1.141 0.95
123_S 141_A 1.134 0.95
457_A 460_L 1.134 0.95
443_A 460_L 1.134 0.95
454_V 458_K 1.131 0.95
6_I 63_L 1.128 0.95
132_K 419_V 1.125 0.95
256_S 264_S 1.12 0.95
16_V 30_L 1.119 0.95
147_G 316_L 1.118 0.95
180_V 220_V 1.108 0.94
5_K 17_E 1.106 0.94
302_D 324_R 1.1 0.94
394_A 398_Q 1.1 0.94
14_V 41_L 1.1 0.94
436_Y 439_L 1.099 0.94
388_K 392_A 1.093 0.94
229_E 282_R 1.093 0.94
345_L 358_A 1.09 0.94
426_R 449_S 1.09 0.94
141_A 344_Q 1.085 0.93
323_S 339_D 1.084 0.93
158_V 406_F 1.077 0.93
160_M 320_V 1.076 0.93
232_R 238_V 1.073 0.93
151_G 302_D 1.064 0.93
138_C 320_V 1.063 0.93
196_D 199_V 1.062 0.92
90_N 96_V 1.06 0.92
201_D 204_S 1.058 0.92
30_L 54_T 1.057 0.92
237_D 290_S 1.057 0.92
217_R 254_E 1.055 0.92
136_L 400_F 1.052 0.92
56_A 60_S 1.047 0.92
82_K 174_Y 1.045 0.92
326_I 343_R 1.039 0.91
179_G 187_G 1.036 0.91
399_R 402_S 1.034 0.91
361_V 428_F 1.034 0.91
427_G 431_I 1.032 0.91
436_Y 453_A 1.026 0.91
109_A 112_R 1.026 0.91
7_V 17_E 1.026 0.91
74_H 107_R 1.025 0.91
103_G 106_E 1.025 0.91
27_Y 44_Q 1.025 0.91
379_G 388_K 1.024 0.91
178_A 240_L 1.021 0.90
451_E 455_E 1.019 0.90
440_P 457_A 1.014 0.90
160_M 296_A 1.009 0.90
360_G 389_L 1.008 0.90
165_R 197_S 1.006 0.90
414_S 417_K 1.004 0.89
187_G 209_Q 1 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1fx0B111000.098Contact Map0.617
2c61A20.95431000.179Contact Map0.601
3oaaA120.95431000.182Contact Map0.71
2qe7A30.95431000.183Contact Map0.715
3vr4D30.95651000.186Contact Map0.665
3gqbB20.95221000.188Contact Map0.62
3mfyA10.96521000.194Contact Map0.597
2r9vA10.95651000.195Contact Map0.745
1fx0A10.97611000.202Contact Map0.601
2ck3A30.95871000.202Contact Map0.77
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 1.7728 seconds.