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OPENSEQ.org

YCII - Protein YciI
UniProt: P0AB55 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11607
Length: 98 (98)
Sequences: 863
Seq/Len: 8.81

YCII
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
4_V 60_T 3.317 1.00
72_Q 76_D 3.076 1.00
68_L 72_Q 2.825 1.00
66_E 70_A 2.34 1.00
15_E 19_S 2.165 1.00
67_S 70_A 2.058 1.00
23_A 26_A 1.75 1.00
69_E 73_A 1.743 1.00
42_P 97_V 1.717 1.00
30_L 34_E 1.7 1.00
2_L 38_L 1.661 1.00
73_A 77_A 1.606 1.00
71_A 75_A 1.597 1.00
39_T 62_I 1.565 1.00
8_Q 88_H 1.55 1.00
26_A 29_Q 1.549 1.00
20_V 83_A 1.517 1.00
39_T 98_F 1.498 1.00
21_R 80_Y 1.475 1.00
22_P 26_A 1.473 1.00
6_Y 43_M 1.462 1.00
43_M 60_T 1.444 0.99
15_E 18_L 1.405 0.99
40_A 80_Y 1.386 0.99
4_V 43_M 1.356 0.99
8_Q 90_S 1.341 0.99
21_R 25_L 1.267 0.98
5_I 71_A 1.244 0.98
16_K 20_V 1.241 0.98
32_H 98_F 1.241 0.98
65_F 74_W 1.217 0.98
23_A 82_A 1.214 0.98
23_A 83_A 1.175 0.97
20_V 23_A 1.157 0.96
78_D 81_V 1.148 0.96
29_Q 33_D 1.135 0.96
65_F 78_D 1.118 0.95
9_D 59_S 1.117 0.95
39_T 94_F 1.115 0.95
31_L 74_W 1.097 0.95
28_L 37_L 1.095 0.95
16_K 19_S 1.084 0.94
61_V 80_Y 1.054 0.93
25_L 28_L 1.039 0.93
10_K 13_S 1.035 0.92
3_Y 91_V 1.034 0.92
30_L 33_D 1.017 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1mwqA2199.90.264Contact Map0.757
4lbhA10.928699.80.299Contact Map0.633
1s7iA10.969499.50.484Contact Map0.52
1mliA100.867399.10.573Contact Map0.023
3znuA100.8673990.582Contact Map0.722
3lo3A280.867310.80.909Contact Map0.647
3hhlA10.9498.30.914Contact Map0.622
2hiyA40.98986.40.918Contact Map0.381
4jo0A10.88785.80.92Contact Map0.382
4f9iA215.20.921Contact Map0.454

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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