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OPENSEQ.org

YBHP - Uncharacterized protein YbhP
UniProt: P0AAW1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13672
Length: 253 (243)
Sequences: 5780
Seq/Len: 23.79

YBHP
Paralog alert: 0.76 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: EX3 YAFD YBHP
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
11_K 250_E 5.571 1.00
46_C 173_A 4.699 1.00
98_V 125_C 3.835 1.00
228_S 252_H 3.453 1.00
231_T 248_S 3.026 1.00
106_H 126_R 2.806 1.00
13_L 248_S 2.791 1.00
46_C 138_V 2.767 1.00
220_I 249_A 2.649 1.00
47_L 50_V 2.647 1.00
233_L 248_S 2.57 1.00
46_C 140_C 2.503 1.00
98_V 140_C 2.502 1.00
43_D 101_R 2.501 1.00
196_I 222_V 2.451 1.00
105_E 128_V 2.343 1.00
229_A 250_E 2.29 1.00
14_T 48_Q 2.274 1.00
14_T 247_L 2.246 1.00
126_R 137_H 2.196 1.00
13_L 42_A 2.017 1.00
128_V 135_A 2.007 1.00
194_D 199_R 1.927 1.00
104_I 127_I 1.88 1.00
44_I 138_V 1.872 1.00
170_V 193_L 1.86 1.00
80_D 103_P 1.824 1.00
48_Q 140_C 1.818 1.00
173_A 220_I 1.81 1.00
222_V 251_I 1.769 1.00
35_D 39_T 1.749 1.00
36_A 40_V 1.745 1.00
12_V 171_L 1.727 1.00
100_S 103_P 1.715 1.00
124_Y 137_H 1.684 1.00
35_D 38_R 1.675 1.00
226_S 252_H 1.648 1.00
50_V 97_A 1.632 1.00
126_R 168_E 1.577 1.00
42_A 45_V 1.576 1.00
220_I 251_I 1.571 1.00
158_A 162_N 1.563 1.00
143_L 153_Q 1.561 1.00
11_K 248_S 1.522 1.00
143_L 154_L 1.521 1.00
189_V 221_Y 1.519 1.00
13_L 40_V 1.493 1.00
195_E 216_R 1.477 1.00
137_H 168_E 1.473 1.00
169_P 225_A 1.464 1.00
152_A 155_A 1.452 1.00
141_V 176_F 1.451 1.00
152_A 156_M 1.451 1.00
20_G 52_G 1.447 1.00
9_S 250_E 1.428 1.00
222_V 227_A 1.427 1.00
162_N 165_P 1.423 1.00
126_R 135_A 1.418 1.00
228_S 250_E 1.417 1.00
130_P 134_K 1.384 0.99
165_P 225_A 1.38 0.99
46_C 98_V 1.376 0.99
32_E 35_D 1.35 0.99
124_Y 139_M 1.347 0.99
155_A 159_E 1.337 0.99
170_V 223_K 1.315 0.99
108_E 124_Y 1.313 0.99
39_T 235_L 1.299 0.99
172_V 221_Y 1.298 0.99
154_L 178_D 1.291 0.99
139_M 161_V 1.287 0.99
122_V 139_M 1.276 0.99
123_L 140_C 1.234 0.98
130_P 133_G 1.234 0.98
40_V 233_L 1.233 0.98
102_Y 127_I 1.23 0.98
196_I 227_A 1.227 0.98
227_A 249_A 1.224 0.98
41_S 101_R 1.173 0.98
194_D 224_N 1.159 0.97
44_I 102_Y 1.15 0.97
15_I 33_L 1.143 0.97
161_V 193_L 1.14 0.97
141_V 172_V 1.137 0.97
100_S 104_I 1.132 0.97
31_P 35_D 1.13 0.97
171_L 222_V 1.126 0.97
124_Y 160_W 1.12 0.96
138_V 173_A 1.11 0.96
197_F 205_A 1.107 0.96
47_L 99_L 1.106 0.96
34_R 38_R 1.104 0.96
44_I 125_C 1.095 0.96
148_A 152_A 1.086 0.96
13_L 45_V 1.086 0.96
141_V 157_L 1.084 0.96
102_Y 130_P 1.084 0.96
200_A 227_A 1.069 0.95
45_V 99_L 1.059 0.95
37_V 42_A 1.056 0.95
80_D 102_Y 1.054 0.95
104_I 107_Y 1.041 0.94
71_E 74_A 1.04 0.94
137_H 170_V 1.038 0.94
160_W 163_E 1.03 0.94
17_I 20_G 1.03 0.94
137_H 164_L 1.027 0.94
49_E 177_N 1.026 0.94
156_M 159_E 1.021 0.93
230_P 249_A 1.017 0.93
15_I 246_P 1.013 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3mprA40.92891000.283Contact Map0.787
3g6sA10.9131000.29Contact Map0.774
4b8cD40.95261000.305Contact Map0.597
3l1wA60.89331000.306Contact Map0.829
3tebA20.94071000.32Contact Map0.793
2j63A20.93281000.322Contact Map0.774
4gz1A20.90511000.323Contact Map0.783
4k6lF10.9131000.326Contact Map0.619
3ngqA10.95651000.332Contact Map0.76
4f1hA10.88141000.332Contact Map0.805

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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