| UniProt: | P0AAI5 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12606 | ||
| Length: | 413 (410) | ||
| Sequences: | 9974 | ||
| Seq/Len: | 24.33 |
| FABF
Paralog alert: 0.57 [within 20: 0.26] - ratio of genomes with paralogs Cluster includes: FABB FABF |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 20_T | 23_S | 3.375 | 1.00 | |
| 256_A | 355_I | 3.365 | 1.00 | |
| 100_R | 184_D | 3.306 | 1.00 | |
| 225_K | 374_E | 3.296 | 1.00 | |
| 354_S | 394_T | 3.026 | 1.00 | |
| 281_A | 321_T | 2.995 | 1.00 | |
| 26_K | 30_A | 2.943 | 1.00 | |
| 88_D | 255_Y | 2.929 | 1.00 | |
| 223_W | 303_A | 2.814 | 1.00 | |
| 259_V | 411_K | 2.785 | 1.00 | |
| 85_A | 240_V | 2.606 | 1.00 | |
| 243_E | 246_H | 2.551 | 1.00 | |
| 171_I | 351_S | 2.5 | 1.00 | |
| 393_Y | 411_K | 2.389 | 1.00 | |
| 63_I | 71_M | 2.337 | 1.00 | |
| 225_K | 371_N | 2.332 | 1.00 | |
| 357_A | 364_P | 2.322 | 1.00 | |
| 35_I | 52_G | 2.3 | 1.00 | |
| 172_G | 261_F | 2.287 | 1.00 | |
| 255_Y | 359_R | 2.213 | 1.00 | |
| 104_A | 177_I | 2.185 | 1.00 | |
| 178_I | 243_E | 2.164 | 1.00 | |
| 242_E | 252_A | 2.151 | 1.00 | |
| 222_P | 337_S | 2.104 | 1.00 | |
| 148_T | 157_S | 2.104 | 1.00 | |
| 244_Y | 413_I | 2.094 | 1.00 | |
| 294_E | 297_Q | 2.087 | 1.00 | |
| 281_A | 285_A | 2.086 | 1.00 | |
| 175_A | 258_L | 2.059 | 1.00 | |
| 351_S | 410_F | 2.03 | 1.00 | |
| 242_E | 250_R | 1.996 | 1.00 | |
| 233_G | 342_L | 1.988 | 1.00 | |
| 82_G | 187_V | 1.982 | 1.00 | |
| 81_A | 236_A | 1.981 | 1.00 | |
| 237_G | 348_A | 1.946 | 1.00 | |
| 8_V | 355_I | 1.943 | 1.00 | |
| 105_I | 238_M | 1.928 | 1.00 | |
| 27_A | 34_G | 1.922 | 1.00 | |
| 24_T | 335_T | 1.879 | 1.00 | |
| 102_G | 186_M | 1.873 | 1.00 | |
| 58_N | 61_D | 1.872 | 1.00 | |
| 239_L | 351_S | 1.871 | 1.00 | |
| 351_S | 396_C | 1.852 | 1.00 | |
| 82_G | 147_L | 1.847 | 1.00 | |
| 5_R | 259_V | 1.835 | 1.00 | |
| 298_I | 393_Y | 1.834 | 1.00 | |
| 246_H | 249_K | 1.833 | 1.00 | |
| 107_S | 143_V | 1.828 | 1.00 | |
| 27_A | 32_Q | 1.816 | 1.00 | |
| 226_E | 371_N | 1.806 | 1.00 | |
| 29_L | 362_A | 1.803 | 1.00 | |
| 362_A | 385_A | 1.786 | 1.00 | |
| 37_L | 49_K | 1.779 | 1.00 | |
| 8_V | 351_S | 1.766 | 1.00 | |
| 183_A | 186_M | 1.751 | 1.00 | |
| 19_N | 23_S | 1.75 | 1.00 | |
| 212_R | 228_D | 1.749 | 1.00 | |
| 297_Q | 393_Y | 1.731 | 1.00 | |
| 187_V | 240_V | 1.727 | 1.00 | |
| 162_T | 165_T | 1.726 | 1.00 | |
| 177_I | 183_A | 1.724 | 1.00 | |
| 83_V | 87_Q | 1.719 | 1.00 | |
| 335_T | 349_V | 1.718 | 1.00 | |
| 366_T | 369_L | 1.715 | 1.00 | |
| 88_D | 253_K | 1.698 | 1.00 | |
| 356_L | 360_D | 1.693 | 1.00 | |
| 15_S | 349_V | 1.677 | 1.00 | |
| 362_A | 387_Q | 1.66 | 1.00 | |
| 244_Y | 248_K | 1.654 | 1.00 | |
| 293_I | 393_Y | 1.654 | 1.00 | |
| 176_R | 180_Y | 1.647 | 1.00 | |
| 224_D | 369_L | 1.632 | 1.00 | |
| 215_N | 218_A | 1.62 | 1.00 | |
| 224_D | 370_D | 1.619 | 1.00 | |
| 226_E | 370_D | 1.613 | 1.00 | |
| 365_P | 385_A | 1.611 | 1.00 | |
| 300_Y | 363_V | 1.586 | 1.00 | |
| 78_G | 147_L | 1.579 | 1.00 | |
| 379_D | 386_R | 1.575 | 1.00 | |
| 283_A | 287_A | 1.562 | 1.00 | |
| 253_K | 359_R | 1.556 | 1.00 | |
| 373_D | 376_C | 1.549 | 1.00 | |
| 281_A | 322_I | 1.524 | 1.00 | |
| 171_I | 241_L | 1.519 | 1.00 | |
| 237_G | 352_I | 1.514 | 1.00 | |
| 52_G | 233_G | 1.51 | 1.00 | |
| 189_G | 238_M | 1.505 | 1.00 | |
| 331_L | 363_V | 1.504 | 1.00 | |
| 144_A | 159_S | 1.504 | 1.00 | |
| 145_G | 402_G | 1.504 | 1.00 | |
| 262_G | 283_A | 1.484 | 1.00 | |
| 78_G | 143_V | 1.483 | 1.00 | |
| 12_G | 81_A | 1.481 | 1.00 | |
| 301_V | 319_V | 1.474 | 1.00 | |
| 82_G | 238_M | 1.471 | 1.00 | |
| 356_L | 359_R | 1.468 | 1.00 | |
| 169_H | 404_T | 1.46 | 1.00 | |
| 361_Q | 392_E | 1.453 | 1.00 | |
| 174_A | 188_A | 1.449 | 1.00 | |
| 100_R | 286_N | 1.443 | 1.00 | |
| 33_S | 219_A | 1.435 | 1.00 | |
| 6_V | 241_L | 1.424 | 1.00 | |
| 97_N | 152_G | 1.424 | 1.00 | |
| 106_G | 166_S | 1.42 | 1.00 | |
| 300_Y | 333_S | 1.417 | 1.00 | |
| 339_T | 349_V | 1.414 | 1.00 | |
| 37_L | 50_F | 1.414 | 1.00 | |
| 392_E | 412_K | 1.413 | 1.00 | |
| 176_R | 179_A | 1.408 | 1.00 | |
| 261_F | 408_L | 1.401 | 0.99 | |
| 337_S | 367_I | 1.391 | 0.99 | |
| 11_L | 21_V | 1.379 | 0.99 | |
| 73_A | 77_Y | 1.377 | 0.99 | |
| 81_A | 238_M | 1.372 | 0.99 | |
| 213_N | 218_A | 1.371 | 0.99 | |
| 169_H | 406_G | 1.37 | 0.99 | |
| 102_G | 183_A | 1.366 | 0.99 | |
| 239_L | 348_A | 1.361 | 0.99 | |
| 24_T | 353_Y | 1.36 | 0.99 | |
| 210_S | 221_R | 1.359 | 0.99 | |
| 86_M | 151_Y | 1.352 | 0.99 | |
| 26_K | 32_Q | 1.345 | 0.99 | |
| 331_L | 386_R | 1.339 | 0.99 | |
| 4_R | 7_V | 1.328 | 0.99 | |
| 22_E | 88_D | 1.321 | 0.99 | |
| 92_E | 95_E | 1.319 | 0.99 | |
| 185_V | 240_V | 1.316 | 0.99 | |
| 262_G | 287_A | 1.305 | 0.99 | |
| 259_V | 393_Y | 1.29 | 0.99 | |
| 171_I | 408_L | 1.288 | 0.99 | |
| 36_S | 55_K | 1.284 | 0.99 | |
| 102_G | 156_P | 1.284 | 0.99 | |
| 397_N | 407_S | 1.277 | 0.99 | |
| 33_S | 368_N | 1.277 | 0.99 | |
| 85_A | 238_M | 1.271 | 0.99 | |
| 255_Y | 355_I | 1.267 | 0.99 | |
| 316_A | 332_V | 1.257 | 0.99 | |
| 293_I | 297_Q | 1.254 | 0.99 | |
| 83_V | 150_M | 1.253 | 0.99 | |
| 337_S | 366_T | 1.249 | 0.99 | |
| 158_I | 173_H | 1.249 | 0.99 | |
| 176_R | 182_D | 1.246 | 0.98 | |
| 338_M | 367_I | 1.236 | 0.98 | |
| 4_R | 243_E | 1.23 | 0.98 | |
| 4_R | 245_E | 1.226 | 0.98 | |
| 210_S | 228_D | 1.224 | 0.98 | |
| 10_G | 88_D | 1.222 | 0.98 | |
| 221_R | 226_E | 1.222 | 0.98 | |
| 174_A | 186_M | 1.221 | 0.98 | |
| 363_V | 382_P | 1.217 | 0.98 | |
| 300_Y | 354_S | 1.215 | 0.98 | |
| 23_S | 26_K | 1.212 | 0.98 | |
| 264_S | 405_N | 1.21 | 0.98 | |
| 285_A | 289_R | 1.196 | 0.98 | |
| 105_I | 189_G | 1.193 | 0.98 | |
| 298_I | 409_I | 1.193 | 0.98 | |
| 15_S | 237_G | 1.189 | 0.98 | |
| 177_I | 182_D | 1.186 | 0.98 | |
| 78_G | 105_I | 1.186 | 0.98 | |
| 184_D | 243_E | 1.183 | 0.98 | |
| 224_D | 371_N | 1.183 | 0.98 | |
| 272_S | 310_A | 1.178 | 0.98 | |
| 319_V | 332_V | 1.174 | 0.98 | |
| 11_L | 352_I | 1.174 | 0.98 | |
| 154_R | 282_L | 1.17 | 0.97 | |
| 260_G | 290_D | 1.168 | 0.97 | |
| 282_L | 286_N | 1.16 | 0.97 | |
| 6_V | 175_A | 1.159 | 0.97 | |
| 112_L | 119_H | 1.15 | 0.97 | |
| 358_L | 410_F | 1.15 | 0.97 | |
| 323_F | 395_L | 1.145 | 0.97 | |
| 101_I | 185_V | 1.144 | 0.97 | |
| 148_T | 265_S | 1.142 | 0.97 | |
| 284_M | 322_I | 1.14 | 0.97 | |
| 211_T | 228_D | 1.137 | 0.97 | |
| 288_L | 298_I | 1.137 | 0.97 | |
| 395_L | 409_I | 1.134 | 0.97 | |
| 363_V | 388_V | 1.132 | 0.97 | |
| 235_G | 342_L | 1.132 | 0.97 | |
| 26_K | 29_L | 1.13 | 0.97 | |
| 342_L | 349_V | 1.13 | 0.97 | |
| 239_L | 352_I | 1.129 | 0.97 | |
| 217_Q | 228_D | 1.129 | 0.97 | |
| 298_I | 323_F | 1.129 | 0.97 | |
| 395_L | 407_S | 1.127 | 0.97 | |
| 176_R | 290_D | 1.127 | 0.97 | |
| 288_L | 293_I | 1.126 | 0.97 | |
| 47_A | 204_G | 1.123 | 0.97 | |
| 86_M | 240_V | 1.118 | 0.96 | |
| 29_L | 385_A | 1.115 | 0.96 | |
| 305_G | 311_G | 1.113 | 0.96 | |
| 175_A | 179_A | 1.112 | 0.96 | |
| 284_M | 397_N | 1.111 | 0.96 | |
| 171_I | 188_A | 1.111 | 0.96 | |
| 13_M | 21_V | 1.107 | 0.96 | |
| 244_Y | 257_E | 1.097 | 0.96 | |
| 218_A | 370_D | 1.096 | 0.96 | |
| 316_A | 380_F | 1.095 | 0.96 | |
| 78_G | 238_M | 1.093 | 0.96 | |
| 335_T | 339_T | 1.092 | 0.96 | |
| 299_G | 392_E | 1.092 | 0.96 | |
| 264_S | 283_A | 1.09 | 0.96 | |
| 354_S | 358_L | 1.086 | 0.96 | |
| 200_V | 232_L | 1.065 | 0.95 | |
| 358_L | 391_M | 1.059 | 0.95 | |
| 20_T | 84_Q | 1.055 | 0.95 | |
| 169_H | 263_M | 1.055 | 0.95 | |
| 22_E | 26_K | 1.053 | 0.95 | |
| 13_M | 24_T | 1.051 | 0.94 | |
| 39_D | 53_L | 1.049 | 0.94 | |
| 305_G | 334_S | 1.043 | 0.94 | |
| 232_L | 343_L | 1.043 | 0.94 | |
| 369_L | 372_P | 1.042 | 0.94 | |
| 245_E | 248_K | 1.041 | 0.94 | |
| 355_I | 410_F | 1.038 | 0.94 | |
| 221_R | 228_D | 1.035 | 0.94 | |
| 175_A | 290_D | 1.035 | 0.94 | |
| 5_R | 257_E | 1.034 | 0.94 | |
| 25_W | 360_D | 1.032 | 0.94 | |
| 47_A | 207_R | 1.021 | 0.93 | |
| 389_S | 392_E | 1.018 | 0.93 | |
| 35_I | 50_F | 1.011 | 0.93 | |
| 361_Q | 412_K | 1.009 | 0.93 | |
| 358_L | 361_Q | 1.009 | 0.93 | |
| 157_S | 265_S | 1.007 | 0.93 | |
| 28_L | 356_L | 1.006 | 0.93 | |
| 104_A | 186_M | 1.002 | 0.92 | |
| 13_M | 352_I | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2vz8A | 2 | 0.9492 | 100 | 0.057 | Contact Map | 0.773 |
| 4jrmD | 4 | 0.9976 | 100 | 0.131 | Contact Map | 0.788 |
| 1e5mA | 1 | 0.9976 | 100 | 0.135 | Contact Map | 0.769 |
| 3o04A | 1 | 0.9952 | 100 | 0.139 | Contact Map | 0.758 |
| 2gqdA | 2 | 0.9952 | 100 | 0.144 | Contact Map | 0.75 |
| 1ox0A | 1 | 0.9879 | 100 | 0.146 | Contact Map | 0.767 |
| 4b7vA | 2 | 0.9976 | 100 | 0.146 | Contact Map | 0.784 |
| 4jgaA | 2 | 0.9976 | 100 | 0.151 | Contact Map | 0.808 |
| 1j3nA | 2 | 0.9879 | 100 | 0.152 | Contact Map | 0.822 |
| 2hg4A | 6 | 0.9685 | 100 | 0.153 | Contact Map | 0.828 |
Sequence Conservation (Image Generated using WebLogo v3)