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OPENSEQ.org
PAL - Peptidoglycan-associated lipoprotein
UniProt: P0A912 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10684
Length: 173 (171)
Sequences: 262
Seq/Len: 1.53
PAL
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PAL YFIB YIAD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
105_V 169_A 3.1 1.00
157_G 162_A 2.647 1.00
74_D 81_R 2.444 1.00
122_G 147_S 2.204 0.99
89_D 136_K 2.033 0.98
91_H 173_Y 1.817 0.96
155_V 165_K 1.727 0.94
89_D 132_Y 1.664 0.93
106_E 148_Y 1.662 0.93
76_D 151_E 1.618 0.91
142_Q 173_Y 1.559 0.89
114_T 132_Y 1.531 0.88
72_Y 112_R 1.491 0.86
155_V 162_A 1.464 0.85
105_V 172_V 1.454 0.84
57_Q 60_L 1.446 0.84
151_E 168_R 1.411 0.82
123_E 145_I 1.403 0.81
72_Y 154_A 1.381 0.80
120_S 153_P 1.367 0.79
94_F 142_Q 1.299 0.74
128_A 145_I 1.294 0.73
108_H 170_V 1.292 0.73
95_L 153_P 1.288 0.73
42_G 103_V 1.282 0.72
111_E 158_H 1.253 0.70
157_G 160_E 1.245 0.69
80_I 84_F 1.237 0.68
136_K 169_A 1.236 0.68
120_S 151_E 1.228 0.68
105_V 143_I 1.225 0.67
114_T 145_I 1.224 0.67
81_R 84_F 1.217 0.67
108_H 123_E 1.207 0.66
142_Q 152_K 1.206 0.65
80_I 173_Y 1.201 0.65
33_S 143_I 1.198 0.65
78_Y 96_R 1.197 0.65
77_K 127_N 1.186 0.64
6_V 13_A 1.185 0.63
84_F 91_H 1.185 0.63
103_V 146_V 1.176 0.63
91_H 150_K 1.176 0.63
78_Y 124_R 1.166 0.62
9_G 13_A 1.162 0.61
56_E 59_R 1.162 0.61
88_L 132_Y 1.156 0.61
74_D 163_Y 1.15 0.60
84_F 120_S 1.141 0.59
84_F 87_M 1.137 0.59
83_D 133_L 1.135 0.59
144_S 148_Y 1.134 0.58
145_I 148_Y 1.134 0.58
82_S 85_A 1.134 0.58
159_D 162_A 1.127 0.58
64_Q 67_Q 1.117 0.57
120_S 138_V 1.107 0.56
116_E 151_E 1.104 0.55
138_V 142_Q 1.1 0.55
71_V 87_M 1.099 0.55
119_I 148_Y 1.096 0.55
114_T 124_R 1.093 0.54
84_F 173_Y 1.092 0.54
74_D 79_D 1.09 0.54
159_D 163_Y 1.088 0.54
75_L 133_L 1.084 0.53
10_L 14_L 1.064 0.51
20_A 29_S 1.059 0.51
105_V 115_P 1.058 0.51
128_A 161_A 1.056 0.50
153_P 166_N 1.047 0.49
80_I 142_Q 1.038 0.49
19_I 87_M 1.038 0.49
112_R 122_G 1.027 0.47
65_L 91_H 1.027 0.47
123_E 127_N 1.025 0.47
75_L 112_R 1.024 0.47
112_R 163_Y 1.021 0.47
55_E 64_Q 1.019 0.47
74_D 77_K 1.019 0.47
76_D 108_H 1.019 0.47
106_E 172_V 1.013 0.46
16_V 80_I 1.004 0.45
109_A 129_V 1.001 0.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2aizP10.77461000.515Contact Map0.356
1r1mA10.68791000.52Contact Map0.337
2hqsH40.63581000.523Contact Map0.468
4b5cA30.78611000.525Contact Map0.459
3ldtA10.91331000.527Contact Map0.17
3td3A80.68211000.534Contact Map0.385
4g4xA10.65321000.535Contact Map0.438
2kgwA10.73991000.54Contact Map0.322
3cypB40.61851000.542Contact Map0.332
2l26A10.98841000.545Contact Map0.154
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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