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OPENSEQ.org

YBGC - Acyl-CoA thioester hydrolase YbgC
UniProt: P0A8Z3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11110
Length: 134 (129)
Sequences: 3475
Seq/Len: 26.94

YBGC
Paralog alert: 0.65 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: FADM YBGC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
61_K 65_E 3.815 1.00
70_A 76_L 2.662 1.00
32_Y 107_A 2.575 1.00
70_A 104_L 2.449 1.00
7_R 77_E 2.364 1.00
68_A 102_T 2.328 1.00
63_T 108_E 2.322 1.00
9_P 75_M 2.296 1.00
79_Q 95_R 2.21 1.00
67_Y 106_E 2.177 1.00
83_T 93_T 2.125 1.00
27_S 30_A 2.114 1.00
29_V 64_V 2.08 1.00
29_V 62_M 2.059 1.00
7_R 79_Q 2.036 1.00
9_P 77_E 1.883 1.00
32_Y 105_N 1.868 1.00
69_P 119_M 1.829 1.00
115_D 118_K 1.828 1.00
94_Q 109_V 1.778 1.00
81_E 93_T 1.762 1.00
35_A 80_T 1.681 1.00
65_E 106_E 1.635 1.00
64_V 105_N 1.586 1.00
126_K 130_A 1.583 1.00
74_D 98_N 1.549 1.00
84_S 91_V 1.543 1.00
88_T 121_P 1.541 1.00
95_R 103_L 1.534 1.00
86_R 89_S 1.526 1.00
97_V 103_L 1.524 1.00
91_V 108_E 1.51 1.00
79_Q 97_V 1.503 1.00
95_R 106_E 1.465 1.00
13_Y 16_D 1.458 1.00
33_E 36_R 1.422 1.00
11_R 41_R 1.389 0.99
23_V 31_F 1.389 0.99
78_I 96_I 1.384 0.99
35_A 78_I 1.382 0.99
15_E 30_A 1.353 0.99
32_Y 96_I 1.334 0.99
11_R 75_M 1.299 0.99
12_V 31_F 1.229 0.98
56_A 116_P 1.218 0.98
11_R 38_E 1.214 0.98
58_V 114_V 1.211 0.98
16_D 30_A 1.192 0.98
81_E 95_R 1.176 0.98
62_M 109_V 1.172 0.98
91_V 110_L 1.168 0.97
49_A 52_A 1.166 0.97
38_E 42_H 1.162 0.97
67_Y 103_L 1.15 0.97
83_T 108_E 1.137 0.97
89_S 110_L 1.135 0.97
125_P 128_I 1.122 0.97
129_V 133_K 1.103 0.96
26_A 30_A 1.062 0.95
32_Y 64_V 1.058 0.95
61_K 110_L 1.058 0.95
88_T 112_V 1.044 0.94
127_S 130_A 1.036 0.94
41_R 73_D 1.034 0.94
8_W 38_E 1.03 0.94
25_H 62_M 1.029 0.94
87_G 123_A 1.028 0.94
16_D 31_F 1.014 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2ownA211000.172Contact Map0.757
2essA111000.188Contact Map0.63
4gakA10.99251000.189Contact Map0.766
2w3xA611000.217Contact Map0.899
3ck1A20.99251000.222Contact Map0.784
2hljA10.99251000.222Contact Map0.704
1s5uA811000.223Contact Map0.928
2gf6A40.98511000.224Contact Map0.782
2hx5A10.992599.90.228Contact Map0.707
2oafA20.992599.90.232Contact Map0.84

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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