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YIHY - UPF0761 membrane protein YihY
UniProt: P0A8K8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11851
Length: 290 (264)
Sequences: 2241
Seq/Len: 8.49

YIHY
Paralog alert: 0.39 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: YHJD YIHY
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
30_D 267_E 4.86 1.00
31_N 126_T 3.13 1.00
216_V 268_I 2.849 1.00
37_G 42_V 2.665 1.00
33_T 260_C 2.6 1.00
197_Y 217_A 2.46 1.00
221_F 258_T 2.186 1.00
213_G 269_T 2.126 1.00
124_L 266_A 2.081 1.00
27_I 32_M 2.012 1.00
23_L 264_L 2.004 1.00
224_G 257_W 1.994 1.00
19_W 23_L 1.913 1.00
212_V 269_T 1.904 1.00
34_T 38_N 1.868 1.00
194_W 207_N 1.867 1.00
232_I 250_I 1.812 1.00
27_I 260_C 1.798 1.00
36_A 263_L 1.792 1.00
139_S 142_V 1.767 1.00
144_W 148_T 1.759 1.00
194_W 214_A 1.756 1.00
31_N 122_S 1.737 1.00
20_L 23_L 1.697 1.00
128_W 269_T 1.68 1.00
23_L 268_I 1.66 1.00
125_N 202_T 1.656 1.00
30_D 129_R 1.612 1.00
216_V 220_L 1.592 1.00
222_E 225_K 1.569 1.00
103_A 107_C 1.547 1.00
125_N 201_P 1.535 1.00
197_Y 265_G 1.531 1.00
39_L 259_W 1.521 1.00
127_I 263_L 1.511 1.00
124_L 200_V 1.494 1.00
125_N 130_S 1.49 1.00
121_D 200_V 1.483 1.00
85_D 88_Q 1.472 1.00
128_W 225_K 1.458 0.99
26_R 271_T 1.433 0.99
228_F 232_I 1.422 0.99
40_A 259_W 1.413 0.99
190_W 218_A 1.409 0.99
221_F 244_V 1.405 0.99
37_G 40_A 1.392 0.99
69_I 73_H 1.388 0.99
26_R 129_R 1.379 0.99
46_S 116_L 1.377 0.99
198_S 207_N 1.367 0.99
219_L 223_A 1.359 0.99
19_W 272_L 1.352 0.99
190_W 215_F 1.346 0.99
217_A 265_G 1.309 0.99
210_A 214_A 1.296 0.98
193_F 221_F 1.279 0.98
33_T 36_A 1.275 0.98
230_L 234_M 1.273 0.98
140_F 143_Y 1.265 0.98
190_W 211_I 1.265 0.98
66_D 69_I 1.261 0.98
254_W 258_T 1.258 0.98
24_W 28_D 1.256 0.98
43_S 255_V 1.249 0.98
42_V 46_S 1.245 0.98
26_R 30_D 1.235 0.98
72_R 76_F 1.22 0.97
112_T 119_S 1.21 0.97
176_V 180_V 1.207 0.97
173_L 215_F 1.201 0.97
211_I 215_F 1.197 0.97
48_V 94_F 1.195 0.97
40_A 256_Y 1.195 0.97
120_I 259_W 1.194 0.97
36_A 260_C 1.192 0.97
27_I 264_L 1.183 0.97
23_L 32_M 1.168 0.96
223_A 227_G 1.164 0.96
48_V 81_P 1.161 0.96
42_V 112_T 1.153 0.96
53_V 117_M 1.137 0.96
56_A 103_A 1.134 0.96
212_V 216_V 1.127 0.95
231_Y 235_F 1.124 0.95
162_S 167_L 1.121 0.95
120_I 123_A 1.12 0.95
194_W 211_I 1.113 0.95
223_A 226_K 1.113 0.95
193_F 262_V 1.109 0.95
127_I 267_E 1.104 0.95
22_L 271_T 1.1 0.95
82_A 85_D 1.097 0.94
116_L 259_W 1.085 0.94
39_L 123_A 1.083 0.94
78_N 81_P 1.081 0.94
26_R 270_V 1.073 0.94
75_I 80_L 1.071 0.93
133_A 202_T 1.07 0.93
35_L 123_A 1.068 0.93
105_G 260_C 1.066 0.93
38_N 119_S 1.065 0.93
17_W 21_K 1.064 0.93
104_V 216_V 1.058 0.93
118_Y 139_S 1.058 0.93
26_R 267_E 1.052 0.93
190_W 194_W 1.046 0.92
214_A 218_A 1.044 0.92
256_Y 261_I 1.038 0.92
89_R 92_E 1.033 0.92
44_L 255_V 1.032 0.92
117_M 121_D 1.031 0.92
21_K 25_Q 1.025 0.91
22_L 275_Y 1.023 0.91
20_L 264_L 1.02 0.91
271_T 274_E 1.012 0.91
92_E 96_A 1.009 0.91
148_T 151_P 1.008 0.90
139_S 143_Y 1.006 0.90
40_A 255_V 1.005 0.90
153_L 216_V 1.002 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3rlfF10.479323.20.954Contact Map0.45
3ukxC10.06980.963Contact Map
3tijA10.334570.964Contact Map0.17
4hg6A10.4694.50.967Contact Map0.106
2kncB10.19314.30.967Contact Map0.87
4g3bA20.06214.10.968Contact Map
4hygA40.52073.80.968Contact Map0.274
4ltoA40.37243.80.968Contact Map0.229
1s4xA10.15173.50.969Contact Map0.952
4jpkA10.22.70.971Contact Map0.202

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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