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OPENSEQ.org

YEEN - Probable transcriptional regulatory protein YeeN
UniProt: P0A8A2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13382
Length: 238 (235)
Sequences: 1613
Seq/Len: 6.86

YEEN
Paralog alert: 0.23 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: YEBC YEEN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
132_D 202_Q 4.001 1.00
109_N 225_D 3.838 1.00
65_D 69_D 3.794 1.00
11_K 15_K 3.567 1.00
96_A 114_F 3.317 1.00
208_S 211_D 3.126 1.00
41_P 51_I 2.98 1.00
143_D 146_H 2.949 1.00
39_P 72_K 2.761 1.00
122_G 126_S 2.663 1.00
182_A 186_A 2.46 1.00
14_A 18_A 2.402 1.00
206_E 236_A 2.31 1.00
6_A 9_V 2.151 1.00
176_D 179_K 2.092 1.00
86_G 114_F 2.065 1.00
135_G 172_T 2.042 1.00
9_V 13_T 2.022 1.00
151_L 156_V 1.941 1.00
146_H 149_E 1.94 1.00
63_V 66_K 1.933 1.00
173_E 176_D 1.858 1.00
117_K 221_A 1.822 1.00
98_T 106_T 1.816 1.00
177_L 195_T 1.788 1.00
113_I 225_D 1.777 1.00
29_E 46_S 1.767 1.00
149_E 153_E 1.763 1.00
172_T 180_G 1.754 1.00
94_I 218_L 1.753 1.00
207_L 215_F 1.734 1.00
5_W 9_V 1.726 1.00
204_E 236_A 1.674 1.00
26_F 57_A 1.662 1.00
219_V 233_H 1.634 1.00
67_A 71_A 1.618 1.00
80_V 103_V 1.617 1.00
94_I 114_F 1.595 1.00
83_R 95_I 1.586 1.00
61_K 65_D 1.584 1.00
87_F 93_M 1.551 0.99
7_N 11_K 1.54 0.99
144_P 163_E 1.497 0.99
51_I 55_K 1.474 0.99
6_A 10_A 1.457 0.99
150_I 189_I 1.447 0.99
174_P 197_L 1.432 0.99
219_V 223_E 1.43 0.99
137_I 172_T 1.427 0.99
12_K 16_D 1.421 0.99
211_D 214_I 1.416 0.99
22_I 57_A 1.413 0.99
7_N 15_K 1.41 0.99
139_F 170_I 1.397 0.99
97_E 230_K 1.39 0.99
162_T 171_Y 1.383 0.99
181_I 185_K 1.377 0.98
137_I 177_L 1.373 0.98
201_A 204_E 1.365 0.98
49_F 53_R 1.365 0.98
178_H 182_A 1.357 0.98
88_G 215_F 1.345 0.98
51_I 68_I 1.335 0.98
1_M 7_N 1.321 0.98
136_V 198_E 1.31 0.98
121_I 124_A 1.305 0.98
147_I 168_I 1.303 0.98
1_M 4_K 1.3 0.98
34_A 72_K 1.293 0.97
60_P 63_V 1.293 0.97
112_T 115_N 1.292 0.97
151_L 161_V 1.277 0.97
23_Y 59_V 1.254 0.97
55_K 60_P 1.248 0.97
69_D 74_G 1.245 0.97
136_V 169_V 1.232 0.96
90_N 211_D 1.226 0.96
207_L 211_D 1.223 0.96
144_P 148_F 1.219 0.96
83_R 97_E 1.217 0.96
183_A 186_A 1.208 0.96
4_K 7_N 1.204 0.96
117_K 217_G 1.197 0.96
136_V 200_I 1.169 0.95
55_K 61_K 1.16 0.94
51_I 64_I 1.154 0.94
59_V 63_V 1.147 0.94
82_G 98_T 1.14 0.94
154_A 183_A 1.126 0.93
113_I 221_A 1.115 0.93
8_I 12_K 1.114 0.93
40_D 43_L 1.112 0.93
32_A 99_L 1.11 0.93
210_E 213_E 1.101 0.92
130_M 202_Q 1.091 0.92
110_V 225_D 1.087 0.91
7_N 10_A 1.086 0.91
108_A 112_T 1.08 0.91
83_R 199_M 1.077 0.91
182_A 185_K 1.077 0.91
62_H 66_K 1.075 0.91
112_T 116_K 1.07 0.91
9_V 15_K 1.068 0.91
28_V 36_Q 1.066 0.90
154_A 180_G 1.061 0.90
148_F 152_L 1.06 0.90
92_S 215_F 1.059 0.90
112_T 117_K 1.046 0.89
215_F 235_V 1.042 0.89
94_I 215_F 1.042 0.89
82_G 100_T 1.039 0.89
82_G 103_V 1.039 0.89
205_V 234_N 1.032 0.88
150_I 187_A 1.031 0.88
88_G 94_I 1.026 0.88
209_P 213_E 1.026 0.88
140_K 193_S 1.025 0.88
130_M 203_S 1.02 0.88
134_T 201_A 1.019 0.88
13_T 19_T 1.002 0.86
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1lfpA10.9874100-0.028Contact Map0.736
1konA10.9874100-0.023Contact Map0.7
4f3qA10.9874100-0.021Contact Map0.697
1mw7A10.9748100-0.017Contact Map0.742
2lqjA10.336140.60.958Contact Map0.475
2jsxA10.310925.20.962Contact Map0.474
2ko1A20.315124.80.962Contact Map0.462
1y7pA30.315117.70.964Contact Map0.611
3l7pA60.319314.40.966Contact Map0.712
4affA10.373914.10.966Contact Map0.506

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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