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OPENSEQ.org
RRF - Ribosome-recycling factor
UniProt: P0A805 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10335
Length: 185 (185)
Sequences: 1679
Seq/Len: 9.08
RRF
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
10_E 166_A 3.263 1.00
121_A 175_L 3.071 1.00
170_K 173_A 2.982 1.00
72_R 96_S 2.901 1.00
161_Q 165_D 2.766 1.00
61_D 64_T 2.721 1.00
20_F 124_A 2.564 1.00
75_S 93_S 2.514 1.00
139_V 153_D 2.498 1.00
169_K 173_A 2.478 1.00
128_V 171_I 2.391 1.00
158_D 162_K 2.364 1.00
107_E 111_K 2.197 1.00
9_A 135_A 2.156 1.00
176_A 180_A 2.152 1.00
20_F 24_I 2.076 1.00
166_A 170_K 2.075 1.00
143_L 153_D 2.017 1.00
54_L 74_M 1.938 1.00
69_V 78_V 1.935 1.00
153_D 157_Q 1.919 1.00
17_V 174_A 1.893 1.00
83_M 90_N 1.893 1.00
121_A 125_R 1.89 1.00
14_D 167_A 1.882 1.00
58_T 66_K 1.861 1.00
180_A 184_Q 1.838 1.00
109_R 112_D 1.777 1.00
40_I 85_S 1.751 1.00
36_L 102_L 1.739 1.00
74_M 77_A 1.714 1.00
89_L 102_L 1.696 1.00
14_D 170_K 1.683 1.00
66_K 97_D 1.659 1.00
173_A 177_D 1.652 1.00
27_I 117_V 1.629 1.00
133_R 137_D 1.626 1.00
79_E 93_S 1.62 1.00
148_I 153_D 1.615 1.00
41_V 48_P 1.609 1.00
119_G 123_Q 1.598 1.00
176_A 179_E 1.595 1.00
44_Y 49_T 1.595 1.00
121_A 171_I 1.591 1.00
7_K 10_E 1.561 1.00
8_D 12_R 1.547 1.00
10_E 14_D 1.504 1.00
136_N 160_V 1.493 1.00
64_T 101_P 1.477 1.00
24_I 174_A 1.471 1.00
37_L 67_I 1.433 0.99
37_L 65_L 1.422 0.99
162_K 165_D 1.421 0.99
155_R 159_D 1.407 0.99
137_D 141_A 1.398 0.99
14_D 18_E 1.392 0.99
71_D 74_M 1.357 0.99
173_A 176_A 1.355 0.99
89_L 100_V 1.352 0.99
107_E 183_M 1.346 0.99
44_Y 71_D 1.305 0.99
50_P 53_Q 1.301 0.99
139_V 160_V 1.285 0.99
43_E 48_P 1.268 0.98
152_D 155_R 1.266 0.98
12_R 131_V 1.244 0.98
59_V 65_L 1.209 0.98
113_L 116_I 1.199 0.97
141_A 145_D 1.194 0.97
40_I 81_A 1.158 0.97
117_V 175_L 1.154 0.97
44_Y 74_M 1.152 0.97
24_I 121_A 1.151 0.97
24_I 175_L 1.145 0.96
19_A 22_T 1.139 0.96
26_K 39_G 1.13 0.96
3_S 7_K 1.12 0.96
54_L 70_F 1.116 0.96
54_L 71_D 1.104 0.95
21_K 174_A 1.103 0.95
34_P 57_V 1.103 0.95
105_L 113_L 1.086 0.95
5_I 9_A 1.085 0.95
128_V 164_T 1.076 0.94
114_T 179_E 1.068 0.94
139_V 156_S 1.059 0.94
11_V 15_K 1.058 0.94
10_E 167_A 1.039 0.93
87_L 100_V 1.036 0.93
109_R 113_L 1.015 0.92
136_N 157_Q 1.009 0.92
13_M 164_T 1.009 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4gfqA11100-0.024Contact Map0.794
1is1A11100-0.02Contact Map0.725
1dd5A11100-0.019Contact Map0.836
1wqgA11100-0.019Contact Map0.747
1iseA11100-0.019Contact Map0.708
1eh1A10.9946100-0.013Contact Map0.699
1ge9A10.97841000.02Contact Map0.533
3lf9A10.61081000.472Contact Map0.634
1wihA10.44321000.498Contact Map0.463
3lhpS20.66491000.529Contact Map0.665
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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