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OPENSEQ.org

RS12 - 30S ribosomal protein S12
UniProt: P0A7S3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10911
Length: 124 (124)
Sequences: 719
Seq/Len: 5.80

RS12
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
54_R 64_T 5.81 1.00
38_Y 52_V 3.56 1.00
30_K 59_N 2.822 1.00
65_S 97_T 2.427 1.00
96_H 116_K 2.042 1.00
25_E 59_N 1.986 1.00
53_C 97_T 1.974 1.00
29_Q 98_V 1.858 1.00
43_K 91_P 1.824 1.00
41_T 49_L 1.771 1.00
27_C 30_K 1.703 1.00
3_T 6_Q 1.617 0.99
97_T 104_C 1.549 0.99
111_K 124_A 1.531 0.99
40_T 52_V 1.509 0.99
25_E 61_F 1.495 0.99
31_R 102_L 1.485 0.99
19_S 22_P 1.473 0.99
15_K 25_E 1.454 0.99
43_K 86_R 1.433 0.98
73_N 105_S 1.422 0.98
29_Q 81_L 1.414 0.98
108_K 111_K 1.411 0.98
66_Y 96_H 1.341 0.97
87_V 96_H 1.311 0.97
14_R 17_A 1.297 0.97
35_T 82_I 1.218 0.95
17_A 20_N 1.218 0.95
112_Q 119_V 1.21 0.94
48_A 76_E 1.205 0.94
68_G 101_A 1.191 0.94
36_R 61_F 1.186 0.94
111_K 122_P 1.177 0.93
17_A 68_G 1.163 0.93
96_H 113_A 1.162 0.93
68_G 104_C 1.156 0.92
29_Q 102_L 1.154 0.92
39_T 49_L 1.123 0.91
21_V 113_A 1.121 0.91
48_A 90_L 1.118 0.91
55_V 77_H 1.096 0.89
36_R 52_V 1.074 0.88
121_R 124_A 1.072 0.88
31_R 62_E 1.059 0.87
22_P 96_H 1.059 0.87
68_G 97_T 1.059 0.87
27_C 38_Y 1.058 0.87
2_A 7_L 1.05 0.87
4_V 7_L 1.048 0.86
32_G 57_L 1.043 0.86
100_G 106_G 1.039 0.86
14_R 26_A 1.037 0.86
61_F 108_K 1.034 0.85
83_R 96_H 1.018 0.84
21_V 26_A 1.018 0.84
21_V 70_E 1.011 0.84
2_A 11_P 1.009 0.83
34_C 78_S 1.005 0.83
11_P 61_F 1.003 0.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vqeL111000.081Contact Map0.481
3j20N10.93551000.396Contact Map0.356
4bpeL10.91131000.405Contact Map0.494
3u5cX10.92741000.407Contact Map0.462
3zeyS10.92741000.419Contact Map0.393
2jpjA10.1293.50.965Contact Map0.594
1jcuA10.524230.966Contact Map0.032
2jroA10.209720.969Contact Map0.662
4bpe010.84681.90.97Contact Map0.456
2q8kA10.33871.90.97Contact Map0.617

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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