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RL33 - 50S ribosomal protein L33
UniProt: P0A7N9 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10891
Length: 55 (54)
Sequences: 1105
Seq/Len: 20.46

RL33
Paralog alert: 0.20 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
18_G 42_V 3.205 1.00
19_H 49_Y 2.946 1.00
35_E 48_I 2.752 1.00
16_G 40_D 2.37 1.00
12_V 52_A 2.263 1.00
15_A 45_Q 1.877 1.00
30_K 34_L 1.844 1.00
6_R 27_K 1.838 1.00
37_K 48_I 1.77 1.00
8_K 22_T 1.671 1.00
40_D 43_V 1.65 1.00
16_G 43_V 1.583 1.00
39_F 44_R 1.57 1.00
30_K 36_L 1.556 1.00
13_S 40_D 1.482 1.00
19_H 52_A 1.481 1.00
26_N 29_T 1.427 1.00
37_K 46_H 1.349 0.99
35_E 50_K 1.299 0.99
23_T 26_N 1.251 0.99
37_K 45_Q 1.225 0.98
13_S 49_Y 1.206 0.98
12_V 19_H 1.192 0.98
7_E 27_K 1.128 0.97
12_V 20_F 1.093 0.96
1_M 5_I 1.074 0.95
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3v2d610.981899.80.02Contact Map0.731
4kix11199.80.023Contact Map0.427
1nkw110.981899.80.028Contact Map0.017
2zjr110.981899.80.042Contact Map0.008
3bbo310.981899.80.068Contact Map0.076
2ftcP10.909199.70.138Contact Map0.032
3j39o10.490978.40.79Contact Map0.746
4a18C10.490978.20.791Contact Map0.797
3j21j10.472777.60.792Contact Map0.887
1vq8310.472777.50.792Contact Map0.765

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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