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OPENSEQ.org

RL19 - 50S ribosomal protein L19
UniProt: P0A7K6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10880
Length: 115 (114)
Sequences: 1157
Seq/Len: 10.15

RL19
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
29_K 83_S 3.565 1.00
50_I 57_S 3.335 1.00
27_E 44_E 3.202 1.00
103_R 107_A 3.081 1.00
46_V 100_L 2.945 1.00
29_K 42_A 2.899 1.00
3_N 6_K 2.77 1.00
31_W 38_K 2.283 1.00
29_K 40_L 2.186 1.00
33_V 36_S 2.125 1.00
90_G 110_I 2.047 1.00
52_N 57_S 2.01 1.00
26_V 47_V 1.988 1.00
31_W 82_D 1.98 1.00
20_F 47_V 1.815 1.00
14_K 77_H 1.797 1.00
13_M 77_H 1.793 1.00
6_K 10_Q 1.779 1.00
21_R 113_R 1.765 1.00
9_E 56_H 1.757 1.00
91_A 113_R 1.721 1.00
8_L 11_E 1.701 1.00
27_E 87_K 1.648 1.00
51_R 56_H 1.601 1.00
29_K 85_S 1.597 1.00
49_A 73_V 1.547 1.00
20_F 59_F 1.528 1.00
91_A 111_K 1.516 1.00
7_Q 10_Q 1.505 1.00
27_E 85_S 1.476 1.00
5_I 9_E 1.463 1.00
44_E 88_R 1.435 1.00
30_V 72_R 1.431 1.00
53_R 57_S 1.366 0.99
50_I 76_T 1.342 0.99
27_E 42_A 1.327 0.99
60_T 73_V 1.305 0.99
16_D 77_H 1.28 0.99
49_A 96_K 1.272 0.99
30_V 74_F 1.235 0.98
7_Q 11_E 1.234 0.98
59_F 81_V 1.216 0.98
9_E 55_L 1.214 0.98
33_V 38_K 1.212 0.98
25_T 46_V 1.197 0.98
33_V 80_V 1.197 0.98
97_L 100_L 1.16 0.97
38_K 82_D 1.143 0.97
5_I 8_L 1.136 0.97
51_R 58_A 1.132 0.97
105_G 108_A 1.122 0.97
48_I 98_Y 1.09 0.96
71_E 101_R 1.085 0.96
6_K 9_E 1.063 0.95
26_V 61_V 1.037 0.94
99_Y 110_I 1.005 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kixP111000.045Contact Map0.805
3j3wP111000.05Contact Map0.167
3v2dT111000.056Contact Map0.763
2zjrM10.99131000.058Contact Map0.47
3bboR10.95651000.167Contact Map0.054
2ftcK10.85221000.225Contact Map0
4hczA20.478321.30.936Contact Map0.685
1zq1A20.817419.70.937Contact Map0.621
1vq8T10.791318.90.937Contact Map0.358
3u5eY10.818.20.938Contact Map0.352

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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