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OPENSEQ.org

RBFA - Ribosome-binding factor A
UniProt: P0A7G2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11178
Length: 133 (123)
Sequences: 1402
Seq/Len: 11.40

RBFA
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
73_Q 76_S 2.866 1.00
54_V 69_I 2.766 1.00
51_K 98_F 2.625 1.00
111_N 115_S 2.504 1.00
48_A 91_I 2.488 1.00
44_S 49_Y 2.264 1.00
19_I 52_V 2.172 1.00
18_E 86_A 2.119 1.00
79_I 95_L 2.065 1.00
13_Q 16_Q 2.011 1.00
80_R 94_E 1.957 1.00
109_M 113_V 1.892 1.00
22_I 79_I 1.832 1.00
49_Y 96_T 1.829 1.00
61_D 64_A 1.75 1.00
84_G 92_V 1.741 1.00
102_S 106_G 1.695 1.00
81_S 85_K 1.671 1.00
110_S 114_T 1.666 1.00
69_I 73_Q 1.616 1.00
78_F 82_L 1.577 1.00
11_V 89_L 1.523 1.00
38_V 54_V 1.492 1.00
51_K 96_T 1.488 1.00
54_V 72_L 1.462 1.00
82_L 86_A 1.461 1.00
45_R 48_A 1.458 1.00
83_L 92_V 1.454 1.00
31_R 75_A 1.448 1.00
66_K 70_K 1.427 1.00
32_L 71_A 1.421 1.00
21_L 86_A 1.416 1.00
41_V 50_A 1.416 1.00
71_A 74_E 1.358 0.99
107_M 111_N 1.343 0.99
19_I 79_I 1.334 0.99
22_I 83_L 1.325 0.99
8_P 12_A 1.322 0.99
105_E 108_R 1.307 0.99
64_A 67_A 1.304 0.99
82_L 85_K 1.296 0.99
12_A 43_M 1.273 0.99
115_S 119_H 1.271 0.99
29_D 71_A 1.242 0.98
71_A 75_A 1.238 0.98
29_D 32_L 1.232 0.98
26_E 82_L 1.216 0.98
14_E 17_K 1.21 0.98
37_T 55_T 1.182 0.98
63_D 67_A 1.15 0.97
15_M 83_L 1.146 0.97
112_L 116_V 1.129 0.97
14_E 18_E 1.116 0.96
108_R 111_N 1.097 0.96
113_V 117_V 1.097 0.96
102_S 105_E 1.088 0.96
65_V 101_N 1.061 0.95
105_E 109_M 1.048 0.94
18_E 22_I 1.035 0.94
55_T 99_Y 1.031 0.94
80_R 92_V 1.03 0.94
30_P 75_A 1.018 0.93
115_S 118_K 1.009 0.93
67_A 70_K 1.008 0.93
44_S 96_T 1.003 0.93
120_D 123_R 1.003 0.93
101_N 105_E 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1josA10.96241000.109Contact Map0.653
1pa4A10.87221000.149Contact Map0.525
2e7gA10.86471000.204Contact Map0.487
2kzfA10.7821000.217Contact Map0.555
2dyjA20.71431000.28Contact Map0.781
1ybxA20.639111.80.929Contact Map0.509
1vpuA10.2038.70.933Contact Map0.582
3odmA80.59470.936Contact Map0.188
3dbiA30.75196.60.937Contact Map0.44
1qpzA10.71434.90.941Contact Map0.183

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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