| UniProt: | P0A7E9 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11539 | ||
| Length: | 241 (234) | ||
| Sequences: | 6398 | ||
| Seq/Len: | 27.34 |
| PYRH
Paralog alert: 0.90 [within 20: 0.10] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 173_A | 178_D | 4.557 | 1.00 | |
| 11_R | 50_Q | 3.568 | 1.00 | |
| 39_Q | 98_A | 3.296 | 1.00 | |
| 228_R | 233_E | 3.248 | 1.00 | |
| 186_Q | 240_T | 2.932 | 1.00 | |
| 52_G | 156_I | 2.868 | 1.00 | |
| 42_K | 46_E | 2.772 | 1.00 | |
| 100_V | 131_V | 2.566 | 1.00 | |
| 169_G | 183_M | 2.524 | 1.00 | |
| 42_K | 100_V | 2.344 | 1.00 | |
| 105_M | 125_L | 2.271 | 1.00 | |
| 160_V | 216_R | 2.25 | 1.00 | |
| 172_T | 178_D | 2.24 | 1.00 | |
| 168_D | 219_N | 2.161 | 1.00 | |
| 153_G | 161_V | 2.122 | 1.00 | |
| 35_D | 97_R | 2.101 | 1.00 | |
| 172_T | 182_T | 2.081 | 1.00 | |
| 101_N | 130_R | 2.071 | 1.00 | |
| 134_L | 152_R | 2.03 | 1.00 | |
| 10_K | 159_D | 2.004 | 1.00 | |
| 35_D | 98_A | 1.984 | 1.00 | |
| 190_S | 209_R | 1.914 | 1.00 | |
| 173_A | 180_T | 1.907 | 1.00 | |
| 168_D | 171_F | 1.886 | 1.00 | |
| 227_R | 231_M | 1.855 | 1.00 | |
| 43_E | 227_R | 1.83 | 1.00 | |
| 42_K | 98_A | 1.805 | 1.00 | |
| 162_L | 218_F | 1.768 | 1.00 | |
| 123_I | 127_R | 1.709 | 1.00 | |
| 193_L | 206_T | 1.677 | 1.00 | |
| 40_E | 224_G | 1.661 | 1.00 | |
| 165_T | 217_V | 1.658 | 1.00 | |
| 45_V | 50_Q | 1.651 | 1.00 | |
| 103_R | 130_R | 1.601 | 1.00 | |
| 170_V | 187_L | 1.588 | 1.00 | |
| 13_L | 158_A | 1.583 | 1.00 | |
| 219_N | 222_K | 1.56 | 1.00 | |
| 122_A | 134_L | 1.545 | 1.00 | |
| 50_Q | 127_R | 1.533 | 1.00 | |
| 36_R | 39_Q | 1.53 | 1.00 | |
| 55_I | 88_G | 1.528 | 1.00 | |
| 55_I | 91_M | 1.525 | 1.00 | |
| 45_V | 131_V | 1.524 | 1.00 | |
| 119_W | 123_I | 1.521 | 1.00 | |
| 154_I | 213_L | 1.501 | 1.00 | |
| 174_D | 177_K | 1.491 | 1.00 | |
| 18_G | 61_F | 1.488 | 1.00 | |
| 45_V | 100_V | 1.473 | 1.00 | |
| 124_S | 128_N | 1.472 | 1.00 | |
| 20_A | 220_M | 1.471 | 1.00 | |
| 188_T | 191_E | 1.463 | 1.00 | |
| 35_D | 39_Q | 1.46 | 1.00 | |
| 38_A | 95_L | 1.448 | 1.00 | |
| 185_E | 234_K | 1.419 | 1.00 | |
| 125_L | 130_R | 1.415 | 1.00 | |
| 59_N | 62_R | 1.4 | 0.99 | |
| 47_L | 231_M | 1.397 | 0.99 | |
| 222_K | 228_R | 1.394 | 0.99 | |
| 38_A | 94_A | 1.374 | 0.99 | |
| 41_I | 131_V | 1.371 | 0.99 | |
| 44_L | 230_V | 1.367 | 0.99 | |
| 168_D | 222_K | 1.362 | 0.99 | |
| 36_R | 40_E | 1.335 | 0.99 | |
| 45_V | 129_N | 1.324 | 0.99 | |
| 164_A | 218_F | 1.323 | 0.99 | |
| 226_L | 229_V | 1.322 | 0.99 | |
| 162_L | 226_L | 1.315 | 0.99 | |
| 172_T | 184_Y | 1.312 | 0.99 | |
| 190_S | 194_E | 1.304 | 0.99 | |
| 192_V | 205_F | 1.293 | 0.99 | |
| 50_Q | 129_N | 1.284 | 0.99 | |
| 42_K | 95_L | 1.269 | 0.99 | |
| 150_C | 208_A | 1.267 | 0.99 | |
| 95_L | 133_I | 1.264 | 0.99 | |
| 152_R | 156_I | 1.263 | 0.99 | |
| 45_V | 51_V | 1.244 | 0.98 | |
| 186_Q | 238_L | 1.244 | 0.98 | |
| 166_K | 176_A | 1.243 | 0.98 | |
| 95_L | 100_V | 1.242 | 0.98 | |
| 124_S | 127_R | 1.226 | 0.98 | |
| 191_E | 195_K | 1.219 | 0.98 | |
| 19_E | 22_Q | 1.217 | 0.98 | |
| 14_L | 41_I | 1.216 | 0.98 | |
| 22_Q | 30_D | 1.214 | 0.98 | |
| 43_E | 47_L | 1.207 | 0.98 | |
| 96_H | 101_N | 1.185 | 0.98 | |
| 171_F | 183_M | 1.185 | 0.98 | |
| 41_I | 53_V | 1.174 | 0.98 | |
| 187_L | 239_I | 1.169 | 0.97 | |
| 175_P | 181_A | 1.167 | 0.97 | |
| 11_R | 123_I | 1.159 | 0.97 | |
| 191_E | 194_E | 1.155 | 0.97 | |
| 225_A | 228_R | 1.155 | 0.97 | |
| 39_Q | 42_K | 1.155 | 0.97 | |
| 188_T | 240_T | 1.147 | 0.97 | |
| 35_D | 94_A | 1.146 | 0.97 | |
| 10_K | 49_I | 1.145 | 0.97 | |
| 189_Y | 206_T | 1.137 | 0.97 | |
| 12_I | 49_I | 1.136 | 0.97 | |
| 121_E | 125_L | 1.126 | 0.97 | |
| 208_A | 215_I | 1.116 | 0.96 | |
| 150_C | 161_V | 1.115 | 0.96 | |
| 31_A | 35_D | 1.113 | 0.96 | |
| 43_E | 46_E | 1.111 | 0.96 | |
| 52_G | 134_L | 1.11 | 0.96 | |
| 75_V | 78_H | 1.095 | 0.96 | |
| 177_K | 198_K | 1.09 | 0.96 | |
| 121_E | 124_S | 1.089 | 0.96 | |
| 184_Y | 187_L | 1.088 | 0.96 | |
| 228_R | 235_E | 1.079 | 0.95 | |
| 107_A | 136_A | 1.072 | 0.95 | |
| 214_P | 241_E | 1.071 | 0.95 | |
| 105_M | 132_V | 1.065 | 0.95 | |
| 103_R | 125_L | 1.064 | 0.95 | |
| 92_R | 102_A | 1.057 | 0.95 | |
| 16_L | 53_V | 1.055 | 0.95 | |
| 170_V | 239_I | 1.053 | 0.95 | |
| 134_L | 156_I | 1.05 | 0.94 | |
| 33_I | 36_R | 1.047 | 0.94 | |
| 18_G | 28_G | 1.045 | 0.94 | |
| 76_G | 80_G | 1.039 | 0.94 | |
| 37_M | 91_M | 1.038 | 0.94 | |
| 189_Y | 205_F | 1.002 | 0.92 | |
| 172_T | 181_A | 1.001 | 0.92 | |
| 52_G | 126_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ybdA | 3 | 0.9876 | 100 | 0.206 | Contact Map | 0.808 |
| 2a1fA | 6 | 0.9917 | 100 | 0.211 | Contact Map | 0.838 |
| 3ek6A | 6 | 0.9834 | 100 | 0.217 | Contact Map | 0.834 |
| 2jjxA | 3 | 0.9959 | 100 | 0.219 | Contact Map | 0.786 |
| 2va1A | 6 | 0.9917 | 100 | 0.22 | Contact Map | 0.797 |
| 3nwyA | 6 | 0.9834 | 100 | 0.224 | Contact Map | 0.813 |
| 1z9dA | 3 | 0.9834 | 100 | 0.234 | Contact Map | 0.754 |
| 4a7wA | 2 | 0.9793 | 100 | 0.237 | Contact Map | 0.787 |
| 3ab4A | 8 | 0.8921 | 100 | 0.281 | Contact Map | 0.866 |
| 2brxA | 2 | 0.9253 | 100 | 0.289 | Contact Map | 0.683 |
Sequence Conservation (Image Generated using WebLogo v3)