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OPENSEQ.org

IHFB - Integration host factor subunit beta
UniProt: P0A6Y1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10441
Length: 94 (92)
Sequences: 2895
Seq/Len: 31.47

IHFB
Paralog alert: 0.56 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: DBHA DBHB IHFA IHFB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
54_H 79_H 3.657 1.00
60_T 69_K 3.037 1.00
23_E 27_K 2.876 1.00
58_P 71_E 2.87 1.00
55_Y 76_Y 2.748 1.00
61_G 72_L 2.591 1.00
36_T 41_E 2.556 1.00
62_R 67_G 2.491 1.00
84_K 88_D 2.466 1.00
8_E 19_A 2.463 1.00
10_L 26_V 2.243 1.00
21_T 24_D 2.211 1.00
53_L 76_Y 2.197 1.00
60_T 71_E 2.175 1.00
56_R 77_V 1.869 1.00
29_M 33_M 1.783 1.00
62_R 69_K 1.651 1.00
37_L 86_L 1.605 1.00
52_S 81_K 1.599 1.00
20_K 24_D 1.532 1.00
42_R 52_S 1.507 1.00
42_R 50_S 1.477 1.00
18_P 21_T 1.454 1.00
37_L 53_L 1.451 1.00
9_R 13_Q 1.424 1.00
22_V 25_A 1.411 1.00
46_R 83_G 1.388 0.99
55_Y 74_G 1.362 0.99
34_A 86_L 1.286 0.99
49_G 80_F 1.26 0.99
58_P 74_G 1.255 0.99
33_M 43_I 1.222 0.98
13_Q 35_S 1.204 0.98
65_K 68_D 1.184 0.98
17_I 22_V 1.145 0.97
8_E 12_T 1.124 0.97
10_L 29_M 1.115 0.96
9_R 32_H 1.072 0.95
13_Q 31_E 1.063 0.95
48_F 51_F 1.057 0.95
38_A 89_R 1.052 0.95
31_E 34_A 1.046 0.94
75_K 91_N 1.043 0.94
9_R 12_T 1.042 0.94
1_M 5_E 1.013 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2o97B10.957499.90.086Contact Map0.633
1mulA10.957499.90.089Contact Map0.78
1b8zA20.957499.90.09Contact Map0.835
2iieA10.989499.90.09Contact Map0.77
1owfB10.989499.90.092Contact Map0.676
1exeA20.989499.90.096Contact Map0.643
3rhiA40.957499.90.097Contact Map0.918
3c4iA20.989499.90.099Contact Map0.881
1p71A20.989499.90.099Contact Map0.836
1owfA10.989499.90.103Contact Map0.689

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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