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OPENSEQ.org

ENGB - Probable GTP-binding protein EngB
UniProt: P0A6P7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11203
Length: 210 (183)
Sequences: 8390
Seq/Len: 45.85

ENGB
Paralog alert: 0.95 [within 20: 0.76] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
45_T 183_K 3.796 1.00
192_K 195_T 3.425 1.00
113_V 143_L 3.361 1.00
176_E 192_K 2.564 1.00
30_A 109_L 2.533 1.00
174_Q 192_K 2.39 1.00
160_N 164_E 2.367 1.00
118_I 144_L 2.25 1.00
143_L 189_L 2.214 1.00
192_K 196_W 2.209 1.00
41_S 180_S 2.183 1.00
69_E 73_G 2.127 1.00
127_Q 165_A 2.037 1.00
31_F 43_L 2.017 1.00
147_A 177_T 1.966 1.00
31_F 113_V 1.884 1.00
115_L 145_T 1.844 1.00
42_A 115_L 1.836 1.00
72_D 194_D 1.82 1.00
113_V 193_L 1.816 1.00
45_T 186_V 1.773 1.00
116_M 142_V 1.769 1.00
67_L 75_R 1.748 1.00
145_T 180_S 1.72 1.00
144_L 177_T 1.705 1.00
151_A 154_A 1.69 1.00
42_A 189_L 1.651 1.00
188_K 191_Q 1.608 1.00
143_L 178_F 1.598 1.00
53_A 66_N 1.586 1.00
161_M 165_A 1.573 1.00
141_L 192_K 1.557 1.00
29_V 193_L 1.536 1.00
67_L 77_V 1.528 1.00
158_Q 161_M 1.511 1.00
74_K 194_D 1.498 1.00
159_L 177_T 1.498 1.00
161_M 164_E 1.492 1.00
159_L 163_R 1.463 1.00
117_D 120_H 1.462 1.00
189_L 193_L 1.458 1.00
44_N 55_T 1.42 1.00
157_A 161_M 1.407 0.99
191_Q 195_T 1.401 0.99
82_Y 102_Y 1.4 0.99
185_G 188_K 1.393 0.99
119_R 149_K 1.386 0.99
160_N 163_R 1.382 0.99
187_D 191_Q 1.369 0.99
27_I 197_F 1.358 0.99
156_K 160_N 1.336 0.99
141_L 176_E 1.333 0.99
142_V 175_V 1.329 0.99
18_I 21_L 1.314 0.99
56_S 61_R 1.308 0.99
113_V 141_L 1.297 0.99
111_G 196_W 1.289 0.99
111_G 193_L 1.269 0.99
42_A 46_L 1.261 0.99
34_R 126_D 1.248 0.99
186_V 190_R 1.241 0.98
47_T 68_F 1.238 0.98
190_R 193_L 1.232 0.98
178_F 189_L 1.215 0.98
139_A 196_W 1.204 0.98
178_F 186_V 1.201 0.98
141_L 196_W 1.196 0.98
114_V 130_I 1.196 0.98
42_A 178_F 1.176 0.98
47_T 52_L 1.171 0.98
88_P 91_M 1.16 0.97
133_A 140_V 1.151 0.97
49_Q 52_L 1.151 0.97
111_G 141_L 1.147 0.97
42_A 186_V 1.143 0.97
26_G 75_R 1.143 0.97
69_E 75_R 1.132 0.97
94_K 97_R 1.129 0.97
42_A 180_S 1.117 0.96
29_V 74_K 1.113 0.96
93_R 96_Q 1.102 0.96
28_E 75_R 1.083 0.96
41_S 178_F 1.082 0.96
107_Q 136_S 1.063 0.95
113_V 189_L 1.057 0.95
127_Q 131_E 1.056 0.95
154_A 157_A 1.055 0.95
37_A 40_S 1.051 0.94
95_W 99_L 1.049 0.94
131_E 134_V 1.044 0.94
114_V 133_A 1.044 0.94
118_I 147_A 1.03 0.94
150_L 155_R 1.024 0.93
128_Q 131_E 1.024 0.93
106_R 112_L 1.017 0.93
174_Q 196_W 1.013 0.93
131_E 135_D 1.006 0.93
147_A 184_Q 1.003 0.93
40_S 53_A 1.001 0.92
82_Y 129_M 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1puiA211000.378Contact Map0.784
1sviA10.92861000.414Contact Map0.762
4dheA20.99521000.42Contact Map0.699
3pqcA20.92861000.434Contact Map0.801
1mkyA10.82381000.435Contact Map0.821
3ievA10.88571000.437Contact Map0.899
4dcuA10.87141000.44Contact Map0.751
1egaA20.85711000.447Contact Map0.74
1wf3A10.84761000.462Contact Map0.78
1xzpA10.92381000.475Contact Map0.612

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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