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OPENSEQ.org
EFTS - Elongation factor Ts
UniProt: P0A6P1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11033
Length: 283 (282)
Sequences: 1337
Seq/Len: 4.74
EFTS
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
271_D 274_A 5.096 1.00
107_D 110_V 3.703 1.00
168_H 236_M 3.623 1.00
188_A 192_E 3.224 1.00
240_K 248_E 3.193 1.00
10_K 14_E 3.065 1.00
182_K 185_D 2.966 1.00
39_E 193_K 2.753 1.00
203_M 212_A 2.669 1.00
195_Y 217_E 2.627 1.00
168_H 234_F 2.47 1.00
244_Q 247_K 2.46 1.00
55_N 79_Q 2.418 1.00
8_L 34_I 2.341 1.00
33_D 36_L 2.332 1.00
76_V 93_A 2.327 1.00
193_K 196_Q 2.31 1.00
63_K 93_A 2.265 1.00
65_K 98_D 2.253 1.00
30_A 40_N 2.229 1.00
183_P 221_K 2.146 1.00
6_A 9_V 2.094 1.00
31_N 36_L 2.039 1.00
192_E 196_Q 1.997 1.00
157_A 255_G 1.978 1.00
165_L 245_L 1.971 1.00
144_G 166_V 1.949 1.00
123_V 129_N 1.948 1.00
196_Q 200_D 1.946 1.00
201_I 219_R 1.923 1.00
228_S 231_G 1.921 1.00
36_L 43_K 1.837 1.00
214_K 217_E 1.836 1.00
183_P 231_G 1.823 1.00
91_A 95_K 1.804 1.00
200_D 204_Q 1.79 1.00
182_K 230_T 1.769 1.00
8_L 11_E 1.764 1.00
195_Y 199_L 1.749 1.00
70_Y 137_A 1.677 0.99
15_R 38_I 1.666 0.99
231_G 243_G 1.655 0.99
65_K 101_V 1.638 0.99
237_E 240_K 1.636 0.99
158_A 166_V 1.63 0.99
243_G 247_K 1.626 0.99
88_G 125_K 1.621 0.99
75_E 134_R 1.62 0.99
74_L 96_V 1.617 0.99
156_V 170_A 1.613 0.99
92_F 122_L 1.607 0.99
99_A 103_G 1.601 0.99
77_N 133_R 1.594 0.99
92_F 119_R 1.589 0.99
106_T 110_V 1.583 0.99
70_Y 104_K 1.569 0.99
114_Q 117_E 1.56 0.99
138_L 255_G 1.541 0.99
199_L 213_E 1.511 0.98
203_M 209_K 1.481 0.98
119_R 132_I 1.46 0.98
87_A 91_A 1.448 0.98
270_T 280_S 1.435 0.98
200_D 203_M 1.425 0.97
94_D 98_D 1.414 0.97
159_K 252_E 1.397 0.97
217_E 221_K 1.39 0.97
215_M 219_R 1.386 0.97
66_I 71_G 1.379 0.97
241_T 244_Q 1.378 0.97
198_Q 220_M 1.369 0.97
104_K 137_A 1.368 0.97
183_P 228_S 1.362 0.96
198_Q 201_I 1.356 0.96
16_T 38_I 1.354 0.96
202_A 219_R 1.351 0.96
98_D 102_A 1.346 0.96
274_A 278_A 1.339 0.96
11_E 15_R 1.334 0.96
277_A 280_S 1.317 0.95
92_F 132_I 1.315 0.95
202_A 215_M 1.314 0.95
202_A 205_S 1.309 0.95
205_S 215_M 1.288 0.95
74_L 97_L 1.287 0.95
18_A 124_A 1.284 0.95
180_F 187_S 1.278 0.94
113_A 116_E 1.247 0.93
136_A 257_I 1.238 0.93
126_I 130_I 1.23 0.93
62_I 153_G 1.227 0.93
96_V 115_F 1.207 0.92
90_Q 94_D 1.202 0.92
112_K 116_E 1.192 0.91
240_K 244_Q 1.191 0.91
199_L 203_M 1.19 0.91
36_L 39_E 1.189 0.91
63_K 97_L 1.185 0.91
138_L 157_A 1.184 0.91
190_V 223_F 1.168 0.90
270_T 278_A 1.156 0.89
225_G 241_T 1.145 0.89
92_F 96_V 1.135 0.88
116_E 120_V 1.134 0.88
143_L 155_L 1.133 0.88
180_F 186_V 1.13 0.88
278_A 281_K 1.129 0.88
56_V 268_V 1.126 0.88
64_T 73_I 1.124 0.88
237_E 248_E 1.121 0.87
199_L 212_A 1.115 0.87
71_G 155_L 1.113 0.87
177_K 260_E 1.113 0.87
154_V 174_A 1.108 0.87
123_V 130_I 1.102 0.86
213_E 217_E 1.101 0.86
36_L 40_N 1.096 0.86
61_V 93_A 1.094 0.86
210_E 214_K 1.086 0.85
199_L 209_K 1.085 0.85
196_Q 199_L 1.085 0.85
193_K 197_V 1.082 0.85
181_I 256_F 1.078 0.84
240_K 245_L 1.07 0.84
224_T 228_S 1.062 0.83
108_V 112_K 1.059 0.83
72_I 137_A 1.056 0.83
75_E 262_G 1.049 0.82
5_T 8_L 1.047 0.82
211_I 215_M 1.036 0.81
165_L 169_I 1.013 0.79
242_V 245_L 1.008 0.79
28_T 31_N 1.006 0.78
111_L 132_I 1.006 0.78
9_V 23_C 1.002 0.78
159_K 254_T 1 0.78
273_A 277_A 1 0.78
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3avxA111000.048Contact Map0.654
1xb2B10.86571000.218Contact Map0.741
1aipC40.66431000.29Contact Map0.729
1tfeA10.48411000.569Contact Map0.753
2cp9A10.197999.80.796Contact Map0.539
1wj7A10.226198.40.898Contact Map0.652
2g3qA10.1519980.908Contact Map0.594
2dahA10.166197.40.919Contact Map0.661
1z96A20.1413970.925Contact Map0.689
2dnaA10.187396.90.925Contact Map0.543
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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