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OPENSEQ.org

CITX - Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
UniProt: P0A6G5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13540
Length: 183 (181)
Sequences: 228
Seq/Len: 1.26

CITX
Paralog alert: 0.16 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
89_S 92_E 2.981 1.00
43_F 64_G 2.563 1.00
39_P 104_L 2.284 0.99
46_V 121_W 2.15 0.98
15_I 23_D 2.132 0.98
18_L 21_S 1.956 0.97
21_S 44_T 1.792 0.94
150_Q 160_T 1.774 0.93
48_P 170_M 1.755 0.93
44_T 92_E 1.715 0.92
67_A 115_H 1.701 0.91
36_H 96_S 1.623 0.88
13_V 54_S 1.562 0.86
115_H 118_G 1.545 0.85
64_G 121_W 1.544 0.85
40_L 44_T 1.493 0.82
45_V 57_T 1.489 0.82
50_P 163_L 1.453 0.80
108_T 123_I 1.424 0.78
122_D 157_R 1.419 0.77
10_H 57_T 1.408 0.77
19_L 119_R 1.366 0.73
146_L 166_L 1.359 0.73
92_E 120_L 1.349 0.72
47_A 121_W 1.307 0.69
3_L 6_E 1.305 0.69
150_Q 154_V 1.297 0.68
29_Q 40_L 1.292 0.67
61_F 64_G 1.287 0.67
23_D 27_A 1.283 0.67
49_G 52_K 1.282 0.67
125_V 173_L 1.265 0.65
61_F 120_L 1.243 0.63
103_D 144_R 1.239 0.63
53_D 58_R 1.235 0.62
32_W 96_S 1.234 0.62
14_S 17_E 1.224 0.61
45_V 125_V 1.223 0.61
41_V 146_L 1.218 0.61
14_S 37_P 1.216 0.60
4_L 7_L 1.216 0.60
152_A 157_R 1.207 0.60
89_S 120_L 1.195 0.58
107_A 165_D 1.19 0.58
18_L 166_L 1.187 0.58
41_V 104_L 1.186 0.58
42_S 94_M 1.182 0.57
3_L 7_L 1.172 0.56
41_V 97_I 1.16 0.55
33_L 40_L 1.159 0.55
134_S 138_Y 1.154 0.55
26_Q 109_I 1.153 0.54
64_G 68_L 1.149 0.54
52_K 157_R 1.144 0.54
60_I 174_L 1.144 0.54
23_D 89_S 1.142 0.53
41_V 164_T 1.133 0.52
3_L 8_A 1.127 0.52
104_L 123_I 1.127 0.52
140_L 147_L 1.119 0.51
2_H 6_E 1.118 0.51
29_Q 92_E 1.114 0.51
47_A 57_T 1.112 0.50
64_G 146_L 1.11 0.50
28_R 54_S 1.107 0.50
2_H 7_L 1.105 0.50
133_L 138_Y 1.104 0.50
147_L 160_T 1.09 0.48
57_T 167_L 1.081 0.47
146_L 169_R 1.079 0.47
101_A 150_Q 1.079 0.47
54_S 57_T 1.075 0.47
132_I 138_Y 1.071 0.46
19_L 122_D 1.071 0.46
49_G 119_R 1.068 0.46
61_F 68_L 1.065 0.46
95_L 127_T 1.062 0.45
2_H 181_N 1.052 0.44
69_R 95_L 1.049 0.44
115_H 153_A 1.047 0.44
15_I 19_L 1.043 0.44
151_S 160_T 1.039 0.43
40_L 117_L 1.037 0.43
48_P 134_S 1.035 0.43
23_D 119_R 1.028 0.42
15_I 154_V 1.025 0.42
41_V 108_T 1.023 0.42
50_P 156_A 1.021 0.41
169_R 173_L 1.021 0.41
95_L 104_L 1.021 0.41
7_L 181_N 1.002 0.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1zavA10.7486130.956Contact Map0.19
1hc7A40.66676.80.961Contact Map0.1
2pt7G20.49735.80.962Contact Map0.098
3ialA20.72685.60.963Contact Map0.041
3h5nA40.78144.50.964Contact Map0.095
1ynwB10.2354.40.965Contact Map0
1pqvS10.3774.30.965Contact Map
3i96A30.57384.10.965Contact Map0.013
2eelA10.267840.965Contact Map0.009
1qfqB10.17493.70.966Contact Map0.235

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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