| UniProt: | P04983 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10814 | ||
| Length: | 501 (490) | ||
| Sequences: | 14351 | ||
| Seq/Len: | 29.29 |
| RBSA
Paralog alert: 0.93 [within 20: 0.28] - ratio of genomes with paralogs Cluster includes: ALSA ARAG GSIA LSRA MGLA MODF RBSA UUP XYLG YBHF YBIT YEJF YHES YJJK YPHE YTFR |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 31_R | 210_D | 4.473 | 1.00 | |
| 9_G | 22_G | 4.396 | 1.00 | |
| 262_N | 270_D | 4.334 | 1.00 | |
| 259_K | 274_T | 4.117 | 1.00 | |
| 21_S | 218_Q | 3.969 | 1.00 | |
| 261_D | 308_Y | 3.887 | 1.00 | |
| 279_E | 464_R | 3.712 | 1.00 | |
| 8_K | 60_T | 3.655 | 1.00 | |
| 295_M | 451_V | 3.536 | 1.00 | |
| 6_Q | 26_N | 3.358 | 1.00 | |
| 60_T | 67_E | 3.355 | 1.00 | |
| 260_V | 263_L | 3.345 | 1.00 | |
| 33_M | 212_T | 3.33 | 1.00 | |
| 7_L | 10_I | 3.209 | 1.00 | |
| 259_K | 310_T | 3.163 | 1.00 | |
| 308_Y | 315_E | 2.999 | 1.00 | |
| 18_K | 21_S | 2.975 | 1.00 | |
| 296_K | 302_L | 2.84 | 1.00 | |
| 269_N | 472_H | 2.74 | 1.00 | |
| 281_L | 466_I | 2.718 | 1.00 | |
| 6_Q | 62_L | 2.626 | 1.00 | |
| 34_A | 208_C | 2.596 | 1.00 | |
| 11_D | 22_G | 2.514 | 1.00 | |
| 379_I | 389_M | 2.506 | 1.00 | |
| 114_D | 117_T | 2.501 | 1.00 | |
| 282_G | 462_S | 2.501 | 1.00 | |
| 328_G | 415_K | 2.494 | 1.00 | |
| 121_E | 124_K | 2.492 | 1.00 | |
| 312_D | 415_K | 2.468 | 1.00 | |
| 64_L | 161_K | 2.466 | 1.00 | |
| 260_V | 273_F | 2.464 | 1.00 | |
| 224_E | 227_S | 2.448 | 1.00 | |
| 47_M | 197_I | 2.359 | 1.00 | |
| 262_N | 272_S | 2.332 | 1.00 | |
| 265_G | 297_V | 2.325 | 1.00 | |
| 185_R | 206_E | 2.297 | 1.00 | |
| 137_K | 141_D | 2.293 | 1.00 | |
| 261_D | 310_T | 2.274 | 1.00 | |
| 128_K | 190_Q | 2.274 | 1.00 | |
| 265_G | 305_T | 2.247 | 1.00 | |
| 13_A | 18_K | 2.227 | 1.00 | |
| 9_G | 24_A | 2.226 | 1.00 | |
| 119_Y | 136_D | 2.212 | 1.00 | |
| 452_S | 458_V | 2.191 | 1.00 | |
| 256_I | 259_K | 2.162 | 1.00 | |
| 277_K | 415_K | 2.083 | 1.00 | |
| 297_V | 304_R | 2.055 | 1.00 | |
| 117_T | 121_E | 2.038 | 1.00 | |
| 80_G | 161_K | 2.031 | 1.00 | |
| 14_F | 54_Y | 2.02 | 1.00 | |
| 264_C | 270_D | 2.006 | 1.00 | |
| 295_M | 418_I | 1.995 | 1.00 | |
| 440_Q | 444_D | 1.979 | 1.00 | |
| 344_G | 394_G | 1.967 | 1.00 | |
| 466_I | 476_E | 1.95 | 1.00 | |
| 11_D | 18_K | 1.949 | 1.00 | |
| 121_E | 159_E | 1.936 | 1.00 | |
| 294_L | 468_M | 1.933 | 1.00 | |
| 264_C | 306_S | 1.911 | 1.00 | |
| 28_Y | 31_R | 1.889 | 1.00 | |
| 7_L | 25_L | 1.838 | 1.00 | |
| 255_D | 277_K | 1.823 | 1.00 | |
| 276_R | 279_E | 1.807 | 1.00 | |
| 82_G | 155_V | 1.801 | 1.00 | |
| 70_F | 79_A | 1.8 | 1.00 | |
| 95_T | 98_E | 1.791 | 1.00 | |
| 212_T | 219_F | 1.787 | 1.00 | |
| 123_D | 127_A | 1.781 | 1.00 | |
| 8_K | 62_L | 1.773 | 1.00 | |
| 7_L | 50_L | 1.768 | 1.00 | |
| 275_L | 281_L | 1.763 | 1.00 | |
| 120_A | 124_K | 1.739 | 1.00 | |
| 261_D | 272_S | 1.724 | 1.00 | |
| 450_L | 461_M | 1.708 | 1.00 | |
| 208_C | 225_V | 1.698 | 1.00 | |
| 72_G | 75_S | 1.697 | 1.00 | |
| 232_S | 235_E | 1.691 | 1.00 | |
| 273_F | 466_I | 1.689 | 1.00 | |
| 134_K | 137_K | 1.686 | 1.00 | |
| 100_I | 157_S | 1.683 | 1.00 | |
| 223_R | 228_L | 1.682 | 1.00 | |
| 29_P | 161_K | 1.68 | 1.00 | |
| 184_I | 194_I | 1.662 | 1.00 | |
| 11_D | 58_A | 1.66 | 1.00 | |
| 93_Q | 140_G | 1.654 | 1.00 | |
| 378_F | 411_M | 1.65 | 1.00 | |
| 377_D | 381_L | 1.648 | 1.00 | |
| 282_G | 458_V | 1.644 | 1.00 | |
| 67_E | 70_F | 1.64 | 1.00 | |
| 299_Y | 418_I | 1.624 | 1.00 | |
| 348_K | 390_E | 1.613 | 1.00 | |
| 138_L | 141_D | 1.59 | 1.00 | |
| 27_V | 162_V | 1.59 | 1.00 | |
| 415_K | 446_L | 1.572 | 1.00 | |
| 378_F | 407_A | 1.564 | 1.00 | |
| 32_V | 184_I | 1.558 | 1.00 | |
| 381_L | 440_Q | 1.553 | 1.00 | |
| 4_L | 193_G | 1.533 | 1.00 | |
| 84_I | 165_M | 1.526 | 1.00 | |
| 475_G | 490_A | 1.522 | 1.00 | |
| 426_V | 434_I | 1.517 | 1.00 | |
| 275_L | 447_S | 1.516 | 1.00 | |
| 396_L | 404_V | 1.502 | 1.00 | |
| 128_K | 186_E | 1.498 | 1.00 | |
| 379_I | 386_T | 1.497 | 1.00 | |
| 388_S | 391_Q | 1.492 | 1.00 | |
| 260_V | 298_L | 1.486 | 1.00 | |
| 466_I | 473_L | 1.484 | 1.00 | |
| 71_T | 75_S | 1.483 | 1.00 | |
| 263_L | 304_R | 1.479 | 1.00 | |
| 393_I | 404_V | 1.479 | 1.00 | |
| 256_I | 274_T | 1.478 | 1.00 | |
| 12_K | 49_V | 1.473 | 1.00 | |
| 367_K | 370_D | 1.465 | 1.00 | |
| 8_K | 24_A | 1.464 | 1.00 | |
| 9_G | 58_A | 1.461 | 1.00 | |
| 221_A | 236_M | 1.455 | 1.00 | |
| 161_K | 192_R | 1.446 | 1.00 | |
| 8_K | 26_N | 1.444 | 1.00 | |
| 342_V | 353_L | 1.438 | 1.00 | |
| 210_D | 222_E | 1.429 | 1.00 | |
| 125_L | 157_S | 1.424 | 1.00 | |
| 277_K | 447_S | 1.419 | 1.00 | |
| 10_I | 49_V | 1.413 | 1.00 | |
| 27_V | 33_M | 1.411 | 1.00 | |
| 262_N | 306_S | 1.404 | 0.99 | |
| 256_I | 276_R | 1.4 | 0.99 | |
| 261_D | 274_T | 1.39 | 0.99 | |
| 117_T | 120_A | 1.389 | 0.99 | |
| 345_M | 349_E | 1.386 | 0.99 | |
| 186_E | 190_Q | 1.38 | 0.99 | |
| 25_L | 212_T | 1.356 | 0.99 | |
| 51_T | 83_I | 1.356 | 0.99 | |
| 376_S | 389_M | 1.349 | 0.99 | |
| 265_G | 302_L | 1.349 | 0.99 | |
| 90_L | 139_V | 1.349 | 0.99 | |
| 182_R | 186_E | 1.343 | 0.99 | |
| 464_R | 476_E | 1.339 | 0.99 | |
| 346_S | 349_E | 1.335 | 0.99 | |
| 280_I | 438_I | 1.332 | 0.99 | |
| 275_L | 416_V | 1.327 | 0.99 | |
| 143_S | 146_D | 1.327 | 0.99 | |
| 332_I | 419_L | 1.325 | 0.99 | |
| 53_I | 85_H | 1.318 | 0.99 | |
| 63_W | 162_V | 1.317 | 0.99 | |
| 374_A | 377_D | 1.314 | 0.99 | |
| 178_E | 206_E | 1.306 | 0.99 | |
| 268_V | 271_V | 1.299 | 0.99 | |
| 198_S | 204_I | 1.298 | 0.99 | |
| 188_K | 209_D | 1.294 | 0.99 | |
| 12_K | 45_T | 1.29 | 0.99 | |
| 47_M | 164_I | 1.289 | 0.99 | |
| 205_F | 226_A | 1.288 | 0.99 | |
| 488_M | 491_A | 1.286 | 0.99 | |
| 279_E | 463_D | 1.283 | 0.99 | |
| 482_A | 486_V | 1.265 | 0.99 | |
| 124_K | 128_K | 1.263 | 0.99 | |
| 352_S | 371_E | 1.263 | 0.99 | |
| 260_V | 309_V | 1.262 | 0.99 | |
| 438_I | 448_I | 1.252 | 0.99 | |
| 376_S | 380_R | 1.249 | 0.99 | |
| 391_Q | 395_L | 1.248 | 0.99 | |
| 178_E | 182_R | 1.226 | 0.98 | |
| 5_L | 63_W | 1.221 | 0.98 | |
| 311_L | 416_V | 1.22 | 0.98 | |
| 263_L | 297_V | 1.219 | 0.98 | |
| 101_F | 122_A | 1.218 | 0.98 | |
| 348_K | 389_M | 1.215 | 0.98 | |
| 185_R | 188_K | 1.212 | 0.98 | |
| 186_E | 189_S | 1.201 | 0.98 | |
| 347_V | 404_V | 1.199 | 0.98 | |
| 478_T | 481_Q | 1.196 | 0.98 | |
| 373_Q | 377_D | 1.195 | 0.98 | |
| 62_L | 67_E | 1.192 | 0.98 | |
| 311_L | 316_V | 1.188 | 0.98 | |
| 479_R | 482_A | 1.184 | 0.98 | |
| 49_V | 61_L | 1.184 | 0.98 | |
| 392_A | 395_L | 1.178 | 0.98 | |
| 3_A | 28_Y | 1.174 | 0.98 | |
| 123_D | 135_S | 1.172 | 0.98 | |
| 13_A | 58_A | 1.172 | 0.98 | |
| 31_R | 209_D | 1.168 | 0.97 | |
| 419_L | 438_I | 1.166 | 0.97 | |
| 47_M | 83_I | 1.157 | 0.97 | |
| 329_I | 416_V | 1.153 | 0.97 | |
| 483_T | 486_V | 1.145 | 0.97 | |
| 350_N | 408_R | 1.143 | 0.97 | |
| 477_F | 490_A | 1.142 | 0.97 | |
| 20_L | 23_A | 1.139 | 0.97 | |
| 97_A | 122_A | 1.138 | 0.97 | |
| 281_L | 449_I | 1.133 | 0.97 | |
| 342_V | 345_M | 1.132 | 0.97 | |
| 14_F | 45_T | 1.127 | 0.97 | |
| 101_F | 118_M | 1.126 | 0.97 | |
| 126_L | 135_S | 1.118 | 0.96 | |
| 11_D | 21_S | 1.115 | 0.96 | |
| 22_G | 218_Q | 1.115 | 0.96 | |
| 142_L | 150_V | 1.113 | 0.96 | |
| 372_Q | 376_S | 1.112 | 0.96 | |
| 119_Y | 123_D | 1.109 | 0.96 | |
| 270_D | 472_H | 1.107 | 0.96 | |
| 264_C | 269_N | 1.105 | 0.96 | |
| 233_L | 237_M | 1.104 | 0.96 | |
| 129_L | 153_A | 1.103 | 0.96 | |
| 341_L | 393_I | 1.097 | 0.96 | |
| 256_I | 277_K | 1.091 | 0.96 | |
| 330_V | 414_P | 1.09 | 0.96 | |
| 14_F | 19_A | 1.085 | 0.96 | |
| 283_V | 466_I | 1.085 | 0.96 | |
| 12_K | 54_Y | 1.083 | 0.96 | |
| 49_V | 56_R | 1.078 | 0.95 | |
| 63_W | 81_I | 1.076 | 0.95 | |
| 44_S | 48_K | 1.075 | 0.95 | |
| 97_A | 119_Y | 1.075 | 0.95 | |
| 268_V | 297_V | 1.073 | 0.95 | |
| 91_I | 102_L | 1.07 | 0.95 | |
| 370_D | 373_Q | 1.069 | 0.95 | |
| 465_I | 482_A | 1.067 | 0.95 | |
| 147_Q | 335_D | 1.065 | 0.95 | |
| 82_G | 160_S | 1.065 | 0.95 | |
| 10_I | 56_R | 1.063 | 0.95 | |
| 84_I | 155_V | 1.063 | 0.95 | |
| 29_P | 193_G | 1.06 | 0.95 | |
| 127_A | 132_R | 1.053 | 0.95 | |
| 208_C | 211_V | 1.048 | 0.94 | |
| 124_K | 127_A | 1.046 | 0.94 | |
| 257_R | 447_S | 1.045 | 0.94 | |
| 66_K | 75_S | 1.043 | 0.94 | |
| 310_T | 315_E | 1.042 | 0.94 | |
| 229_T | 232_S | 1.04 | 0.94 | |
| 273_F | 294_L | 1.032 | 0.94 | |
| 223_R | 227_S | 1.03 | 0.94 | |
| 13_A | 57_D | 1.03 | 0.94 | |
| 34_A | 204_I | 1.027 | 0.94 | |
| 297_V | 309_V | 1.021 | 0.93 | |
| 92_P | 147_Q | 1.021 | 0.93 | |
| 181_F | 206_E | 1.02 | 0.93 | |
| 7_L | 61_L | 1.019 | 0.93 | |
| 257_R | 312_D | 1.009 | 0.93 | |
| 256_I | 310_T | 1.006 | 0.93 | |
| 291_R | 421_E | 1.002 | 0.92 | |
| 159_E | 190_Q | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4finA | 2 | 0.9162 | 100 | 0.214 | Contact Map | 0.754 |
| 3g5uA | 2 | 0.9721 | 100 | 0.236 | Contact Map | 0.65 |
| 4f4cA | 1 | 0.9681 | 100 | 0.239 | Contact Map | 0.715 |
| 1yqtA | 1 | 0.9222 | 100 | 0.279 | Contact Map | 0.655 |
| 2iw3A | 2 | 0.8743 | 100 | 0.284 | Contact Map | 0.729 |
| 3bk7A | 1 | 0.9222 | 100 | 0.287 | Contact Map | 0.631 |
| 3ozxA | 2 | 0.9082 | 100 | 0.294 | Contact Map | 0.684 |
| 3j16B | 1 | 0.9301 | 100 | 0.306 | Contact Map | 0.481 |
| 3ux8A | 1 | 0.9481 | 100 | 0.314 | Contact Map | 0.593 |
| 2r6fA | 2 | 0.9701 | 100 | 0.418 | Contact Map | 0.64 |
Sequence Conservation (Image Generated using WebLogo v3)