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OPENSEQ.org
OMPF - Outer membrane protein F
UniProt: P02931 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10671
Length: 362 (354)
Sequences: 2458
Seq/Len: 6.94
OMPF
Paralog alert: 0.84 [within 20: 0.14] - ratio of genomes with paralogs
Cluster includes: NMPC OMPC OMPF OMPN PHOE YEDS
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
82_Q 107_F 4.085 1.00
69_G 81_G 3.168 1.00
78_T 111_K 3.12 1.00
163_N 175_F 3.077 1.00
36_Y 66_G 2.998 1.00
77_L 110_L 2.912 1.00
297_Y 315_N 2.903 1.00
209_I 240_L 2.856 1.00
330_S 359_V 2.738 1.00
70_E 78_T 2.714 1.00
322_T 330_S 2.657 1.00
161_Y 164_S 2.527 1.00
80_Y 109_G 2.496 1.00
80_Y 119_D 2.493 1.00
247_I 285_Y 2.483 1.00
215_A 234_E 2.472 1.00
291_L 321_A 2.443 1.00
41_G 89_G 2.375 1.00
211_G 236_W 2.371 1.00
325_F 331_T 2.278 1.00
68_K 82_Q 2.189 1.00
299_K 315_N 2.155 1.00
35_L 67_F 2.152 1.00
177_V 198_G 2.107 1.00
244_A 249_L 2.102 1.00
129_D 160_T 2.088 1.00
35_L 65_L 2.073 1.00
158_V 178_Q 2.021 1.00
36_Y 84_E 2.006 1.00
175_F 200_I 1.973 1.00
40_V 332_Y 1.972 1.00
118_F 159_A 1.94 1.00
77_L 112_Y 1.913 1.00
97_A 103_T 1.905 1.00
73_I 79_G 1.892 1.00
292_R 324_Y 1.887 1.00
126_V 176_A 1.879 1.00
80_Y 117_S 1.877 1.00
331_T 358_I 1.856 1.00
100_G 156_G 1.853 1.00
90_N 183_N 1.813 1.00
253_Y 277_Q 1.799 1.00
39_A 89_G 1.798 1.00
122_R 156_G 1.777 1.00
105_L 124_Y 1.742 1.00
38_K 64_R 1.737 1.00
72_Q 76_D 1.734 1.00
165_N 171_D 1.724 1.00
84_E 104_R 1.71 1.00
246_N 285_Y 1.703 1.00
64_R 84_E 1.7 1.00
85_Y 101_N 1.684 1.00
255_E 277_Q 1.682 1.00
64_R 104_R 1.682 1.00
291_L 323_Y 1.671 1.00
295_I 317_F 1.638 1.00
126_V 178_Q 1.623 1.00
98_Q 103_T 1.62 1.00
330_S 361_Q 1.609 1.00
207_F 242_Y 1.604 1.00
329_M 360_Y 1.603 1.00
85_Y 94_G 1.597 1.00
100_G 103_T 1.59 1.00
164_S 170_V 1.584 1.00
120_Y 159_A 1.566 1.00
209_I 238_T 1.54 0.99
328_N 360_Y 1.53 0.99
335_Y 352_D 1.529 0.99
250_A 282_V 1.501 0.99
159_A 181_G 1.498 0.99
207_F 240_L 1.492 0.99
211_G 238_T 1.488 0.99
297_Y 317_F 1.487 0.99
105_L 123_N 1.486 0.99
293_P 321_A 1.473 0.99
213_Y 234_E 1.468 0.99
174_N 201_S 1.461 0.99
86_N 104_R 1.457 0.99
134_T 208_G 1.448 0.99
336_I 340_I 1.447 0.99
163_N 170_V 1.442 0.99
65_L 85_Y 1.437 0.99
130_A 210_V 1.43 0.99
251_A 281_L 1.427 0.99
111_K 117_S 1.425 0.99
36_Y 82_Q 1.402 0.99
119_D 123_N 1.402 0.99
77_L 114_D 1.4 0.99
287_F 293_P 1.399 0.99
213_Y 236_W 1.374 0.98
92_S 102_K 1.365 0.98
155_V 195_G 1.362 0.98
5_N 9_V 1.36 0.98
71_T 326_N 1.356 0.98
284_Q 292_R 1.346 0.98
64_R 154_R 1.335 0.98
17_A 21_N 1.334 0.98
61_T 359_V 1.328 0.98
88_Q 93_E 1.32 0.98
333_V 354_V 1.313 0.98
24_E 31_N 1.309 0.98
115_V 161_Y 1.302 0.98
104_R 154_R 1.3 0.98
80_Y 111_K 1.293 0.98
215_A 232_K 1.286 0.97
86_N 103_T 1.282 0.97
112_Y 115_V 1.265 0.97
77_L 115_V 1.264 0.97
155_V 158_V 1.255 0.97
38_K 361_Q 1.251 0.97
40_V 58_G 1.249 0.97
82_Q 105_L 1.244 0.97
296_A 318_E 1.242 0.97
237_A 254_G 1.239 0.97
119_D 162_R 1.233 0.96
174_N 203_E 1.229 0.96
119_D 160_T 1.221 0.96
80_Y 107_F 1.22 0.96
88_Q 91_N 1.213 0.96
249_L 283_A 1.207 0.96
333_V 356_V 1.206 0.96
241_K 250_A 1.2 0.96
71_T 328_N 1.19 0.95
25_I 35_L 1.189 0.95
158_V 180_L 1.185 0.95
326_N 329_M 1.174 0.95
126_V 199_S 1.169 0.95
243_D 246_N 1.168 0.95
314_V 338_N 1.147 0.94
173_L 204_Y 1.144 0.94
127_V 235_Q 1.124 0.93
36_Y 68_K 1.121 0.93
178_Q 197_G 1.12 0.93
247_I 251_A 1.117 0.93
286_Q 292_R 1.106 0.93
44_Y 355_A 1.101 0.92
208_G 241_K 1.098 0.92
62_Y 103_T 1.097 0.92
55_G 90_N 1.093 0.92
97_A 100_G 1.092 0.92
5_N 11_V 1.09 0.92
243_D 285_Y 1.08 0.91
203_E 208_G 1.078 0.91
206_G 242_Y 1.072 0.91
115_V 118_F 1.069 0.91
4_R 7_L 1.067 0.91
4_R 8_A 1.066 0.91
332_Y 357_G 1.066 0.91
127_V 212_A 1.061 0.90
8_A 11_V 1.056 0.90
77_L 113_A 1.053 0.90
68_K 117_S 1.049 0.90
160_T 178_Q 1.048 0.90
24_E 27_N 1.045 0.89
123_N 160_T 1.042 0.89
314_V 340_I 1.036 0.89
5_N 10_I 1.032 0.89
165_N 174_N 1.029 0.88
170_V 175_F 1.021 0.88
78_T 113_A 1.021 0.88
42_L 355_A 1.018 0.88
241_K 248_Y 1.016 0.88
290_G 324_Y 1.016 0.88
163_N 172_G 1.013 0.87
5_N 8_A 1.01 0.87
288_D 291_L 1.009 0.87
137_L 320_G 1.008 0.87
278_D 300_S 1.006 0.87
5_N 15_L 1.005 0.87
180_L 183_N 1.001 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2zfgA10.93651000.201Contact Map0.695
2j1nA30.90331000.21Contact Map0.718
3nsgA30.92271000.21Contact Map0.733
1phoA10.90331000.221Contact Map0.68
2fgqX10.84531000.258Contact Map0.742
4auiA30.86741000.266Contact Map0.76
3vy8X10.90331000.285Contact Map0.74
3prnA10.75691000.367Contact Map0.522
2porA10.79011000.376Contact Map0.538
2o4vA30.911698.60.851Contact Map0.594
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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