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RL15 - 50S ribosomal protein L15
UniProt: P02413 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10876
Length: 144 (144)
Sequences: 1568
Seq/Len: 10.89

RL15
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
132_R 136_E 4.019 1.00
124_G 127_V 3.4 1.00
123_R 143_E 3.153 1.00
91_D 94_T 3.113 1.00
17_K 27_L 3.009 1.00
112_L 130_G 2.936 1.00
129_K 132_R 2.736 1.00
127_V 142_I 2.715 1.00
121_T 141_K 2.514 1.00
27_L 32_G 2.254 1.00
80_S 113_A 2.183 1.00
83_A 117_T 2.126 1.00
92_L 125_L 1.92 1.00
93_N 97_A 1.909 1.00
76_E 128_T 1.885 1.00
81_D 84_K 1.855 1.00
116_V 120_V 1.73 1.00
82_L 120_V 1.721 1.00
127_V 132_R 1.712 1.00
36_K 40_S 1.712 1.00
129_K 133_A 1.711 1.00
90_V 120_V 1.677 1.00
19_L 31_G 1.666 1.00
29_K 35_H 1.657 1.00
110_V 124_G 1.637 1.00
19_L 33_R 1.627 1.00
9_A 12_S 1.605 1.00
83_A 118_T 1.578 1.00
89_V 94_T 1.571 1.00
78_R 112_L 1.562 1.00
133_A 137_A 1.557 1.00
87_G 119_P 1.554 1.00
91_D 123_R 1.515 1.00
110_V 135_I 1.509 1.00
82_L 122_V 1.506 1.00
23_I 29_K 1.5 1.00
133_A 136_E 1.483 1.00
2_R 5_T 1.467 1.00
79_L 134_A 1.454 1.00
8_P 12_S 1.394 0.99
115_E 134_A 1.386 0.99
109_K 126_R 1.38 0.99
35_H 40_S 1.379 0.99
51_E 60_R 1.379 0.99
132_R 144_E 1.376 0.99
94_T 98_A 1.364 0.99
136_E 141_K 1.355 0.99
47_R 58_Y 1.336 0.99
16_G 19_L 1.334 0.99
110_V 122_V 1.324 0.99
89_V 121_T 1.312 0.99
78_R 111_I 1.283 0.99
39_K 45_G 1.221 0.98
30_T 35_H 1.219 0.98
135_I 140_G 1.181 0.98
81_D 100_I 1.179 0.98
55_M 58_Y 1.148 0.97
81_D 113_A 1.146 0.97
110_V 127_V 1.137 0.97
92_L 101_I 1.133 0.97
71_A 74_T 1.104 0.96
57_L 61_L 1.092 0.96
33_R 40_S 1.084 0.96
15_A 27_L 1.083 0.96
119_P 141_K 1.075 0.95
79_L 112_L 1.075 0.95
30_T 36_K 1.069 0.95
35_H 39_K 1.059 0.95
94_T 97_A 1.045 0.94
19_L 32_G 1.041 0.94
50_F 54_Q 1.037 0.94
90_V 95_L 1.011 0.93
124_G 135_I 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3j3wL111000.014Contact Map0.337
4kixL111000.035Contact Map0.547
2zjrI10.98611000.044Contact Map0.363
3v2dP10.97921000.058Contact Map0.629
3bboN111000.103Contact Map0.193
1vq8L10.8751000.319Contact Map0.519
4a17K10.91671000.347Contact Map0.384
3o58Y10.8751000.377Contact Map0.046
3j39a10.86811000.38Contact Map0.533
3j21L10.84721000.4Contact Map0.574

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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