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AK1H - Bifunctional aspartokinase/homoserine dehydrogenase 1
UniProt: P00561 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10998
Length: 820 (815)
Sequences: 364
Seq/Len: 0.45

AK1H
Paralog alert: 0.70 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: AK1H AK2H
GREMLIN Results:
  • No predictions exist for P00561
  • Not enough sequences to perform GREMLIN analysis on (0.45 < 1)
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3c1mA40.56221000.68Contact Map
2j0wA10.5391000.683Contact Map
2cdqA20.5721000.687Contact Map
3tviA120.52931000.708Contact Map
3ab4A80.49761000.726Contact Map
3l76A20.49631000.73Contact Map
1ebfA20.42441000.756Contact Map
3do5A10.38781000.802Contact Map
3ingA10.38051000.815Contact Map
2ejwA40.37441000.82Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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